Results 111 to 120 of about 23,057 (164)

Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

BMC Proceedings, 2012
Locasale Jason W, Grassian Alexandra, Beroukhim Rameen, Meyerson Matthew, Wagner Gerhard, Asara John M, Brugge Joan S, Vander Heiden Matthew G, Cantley Lewis C   +8 more
doaj   +1 more source

Yap/Taz activity is associated with increased expression of phosphoglycerate dehydrogenase that supports myoblast proliferation. [PDF]

Cell Tissue Res
Meinhold M, Verbrugge S, Shi A, Schönfelder M, Becker L, Jaspers RT, Zammit PS, Wackerhage H.   +7 more
europepmc   +1 more source

Mediation of the allosteric response of 3‐phosphoglycerate dehydrogenase from peas [PDF]

FEBS Letters, 1976
openaire   +2 more sources

Stability & Flexibility of 3‐Phosphoglycerate Dehydrogenase

The FASEB Journal, 2006
Thai Vo, Christina Cochoran, Chateece Chappell, Olu Taylor, Ellis Bell   +4 more
openaire   +1 more source

Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells. [PDF]

Bioorg Med Chem Lett, 2019
Mullarky E, Xu J, Robin AD, Huggins DJ, Jennings A, Noguchi N, Olland A, Lakshminarasimhan D, Miller M, Tomita D, Michino M, Su T, Zhang G, Stamford AW, Meinke PT, Kargman S, Cantley LC.   +16 more
europepmc   +1 more source

Identification and Biochemical Characterization of the Serine Biosynthetic Enzyme 3-Phosphoglycerate Dehydrogenase in Marchantia polymorpha. [PDF]

Front Plant Sci, 2018
Akashi H, Okamura E, Nishihama R, Kohchi T, Hirai MY.   +4 more
europepmc   +1 more source

Enhanced vulnerability to oxidative stress and induction of inflammatory gene expression in 3-phosphoglycerate dehydrogenase-deficient fibroblasts. [PDF]

FEBS Open Bio, 2018
Hamano M, Haraguchi Y, Sayano T, Zyao C, Arimoto Y, Kawano Y, Moriyasu K, Udono M, Katakura Y, Ogawa T, Kato H, Furuya S.   +11 more
europepmc   +1 more source

Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors. [PDF]

Bioorg Med Chem, 2018
Rohde JM, Brimacombe KR, Liu L, Pacold ME, Yasgar A, Cheff DM, Lee TD, Rai G, Baljinnyam B, Li Z, Simeonov A, Hall MD, Shen M, Sabatini DM, Boxer MB.   +14 more
europepmc   +1 more source

Phosphoglycerate dehydrogenase is a novel predictor for poor prognosis in gastric cancer. [PDF]

Onco Targets Ther, 2016
Xian Y, Zhang S, Wang X, Qin J, Wang W, Wu H.   +5 more
europepmc   +1 more source

α-Ketothioamide Derivatives: A Promising Tool to Interrogate Phosphoglycerate Dehydrogenase (PHGDH). [PDF]

J Med Chem, 2017
Ravez S, Corbet C, Spillier Q, Dutu A, Robin AD, Mullarky E, Cantley LC, Feron O, Frédérick R.   +8 more
europepmc   +1 more source