Results 131 to 140 of about 23,057 (164)
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The gene encoding rat 3-phosphoglycerate dehydrogenase
Mammalian Genome, 2000info:eu-repo/semantics ...
Robbi, M. +3 more
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Stereospecificity of hydrogen transfer by phosphoglycerate dehydrogenase
Biochimica et Biophysica Acta (BBA) - Enzymology, 1975Phosphoglycerate dehydrogenase (EC 1.1.1.95) has been shown to be A site specific in its hydrogen transfer capacity unlike other dehydrogenases which use phosphorylated substrates. The experiments have been carried out using a coupled assay system with yeast alcohol dehydrogenase. The specific activity measurements of the reaction products indicate the
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Low Phosphoglycerate Dehydrogenase Levels Drive Metastatic Dissemination
Cancer Discovery, 2022Abstract Heterogeneous expression of phosphoglycerate dehydrogenase (PHGDH) promotes early metastasis.
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A conformational change in phosphoglycerate dehydrogenase induced by a shift in pH
Biochimica et Biophysica Acta (BBA) - Enzymology, 1977The fluorescence of NADH bound to phosphoglycerate dehydrogenase (3-phosphoglycerate: NAD+ oxidoreductase, EC 1.1.1.95) decreased by 42% between pH 8.5 and 7.0 Serine, an allosteric inhibitor, quenched the fluorescence of enzyme-bound NADH by 29% at pH 8.5, but not at all at pH 7.0.
R, Dubrow, L I, Pizer
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Hepatology, 2017
Up‐regulated glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) is observed in multiple cancers with unclear mechanism. Using GAPDH transgenic mouse and a mouse model of diethylnitrosamine‐induced hepatocellular carcinoma (HCC), here we show that GAPDH overexpression aggravated tumor development by activating cell proliferation and inflammation.
Shanshan, Liu +13 more
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Up‐regulated glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) is observed in multiple cancers with unclear mechanism. Using GAPDH transgenic mouse and a mouse model of diethylnitrosamine‐induced hepatocellular carcinoma (HCC), here we show that GAPDH overexpression aggravated tumor development by activating cell proliferation and inflammation.
Shanshan, Liu +13 more
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[44] d-3-phosphoglycerate dehydrogenase
1966Publisher Summary This chapter discusses the determination of D-3-phosphoglycerate dehydrogenase. Because of the greater stability and availability of D-3-phosphoglycerate (3-PGA), as compared to phosphohydroxypyruvate, the most convenient assay for the enzyme is a spectrophotometric measurement of the increase in optical density at 340 mμ, the ...
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[178] 3-phosphoglycerate dehydrogenase (Escherichia coli)
1971Publisher Summary This chapter discusses the methods of preparation of 3-Phosphoglycerate Dehydrogenase (Escherichia coli). Phosphoglycerate dehydrogenase catalyzes the oxidation of 3-phosphoglycerate (PGA) to hydroxypyruvate phosphate (HPAP). This is the initial reaction in serine biosynthesis, and the enzyme from E.
Lewis I. Pizer, Etsuro Sugimoto
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Phosphoglycerate Dehydrogenase Deficiency (PHGDHD)
2023Amirmohammad Sharafi, Nima Rezaei
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