Results 131 to 140 of about 170,695 (197)

Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism. [PDF]

EMBO J, 2022
Shu Y, Hao Y, Feng J, Liu H, Li ST, Feng J, Jiang Z, Ye L, Zhou Y, Sun Y, Zhou Z, Wei H, Gao P, Zhang H, Sun L.   +14 more
europepmc   +1 more source

Serine Metabolism Regulates the Replicative Senescence of Human Dental Pulp Cells through Histone Methylation

Current Issues in Molecular Biology
Tissue regeneration therapy based on human dental pulp cells (hDPCs) faces the distinct challenge of cellular senescence during massive expansion in vitro.
Shuhan Zhou, Jingyao Cui, Yu Shi
doaj   +1 more source

Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine. [PDF]

J Clin Invest, 2021
Zhang Y, Yu H, Zhang J, Gao H, Wang S, Li S, Wei P, Liang J, Yu G, Wang X, Li X, Li D, Yang W.   +12 more
europepmc   +1 more source

Diversified amino acid-mediated allosteric regulation of phosphoglycerate dehydrogenase for serine biosynthesis in land plants. [PDF]

Biochem J, 2021
Okamura E, Ohtaka K, Nishihama R, Uchida K, Kuwahara A, Mochida K, Hirai MY.   +6 more
europepmc   +1 more source

Erratum: Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase: Erratum. [PDF]

Theranostics, 2021
Dong JK, Lei HM, Liang Q, Tang YB, Zhou Y, Wang Y, Zhang S, Li WB, Tong Y, Zhuang G, Zhang L, Chen HZ, Zhu L, Shen Y.   +13 more
europepmc   +1 more source

D-3-Phosphoglycerate Dehydrogenase [PDF]

, 2020
openaire   +1 more source

PHGDH mediated serine biosynthesis metabolism suppresses vascular calcification

Biology Direct
Background Vascular calcification is a major pathological process driving cardiovascular morbidity and mortality, yet effective therapies are lacking.
Liao Tan, Jie Liu, Ruizheng Shi, Yubo Liu   +3 more
doaj   +1 more source

Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma. [PDF]

Cell Rep, 2021
Rathore R, Caldwell KE, Schutt C, Brashears CB, Prudner BC, Ehrhardt WR, Leung CH, Lin H, Daw NC, Beird HC, Giles A, Wang WL, Lazar AJ, Chrisinger JSA, Livingston JA, Van Tine BA.   +15 more
europepmc   +1 more source

Post-translational regulation of human D-3-phosphoglycerate dehydrogenase in Alzheimer's disease. [PDF]

Protein Sci
Zerbini E, Riva D, Maffioli E, Tedeschi G, Sacchi S, Pollegioni L.   +5 more
europepmc   +1 more source

Exercise Reprograms the Spatial Function of Phosphoglycerate Dehydrogenase of a Pathogenic Nuclear Transcription Factor (PHGDH): A Narrative Review. [PDF]

Metabolites
Yang D, Guo W, Guo L.
europepmc   +1 more source