Results 151 to 160 of about 170,695 (197)

Enhanced vulnerability to oxidative stress and induction of inflammatory gene expression in 3-phosphoglycerate dehydrogenase-deficient fibroblasts. [PDF]

FEBS Open Bio, 2018
Hamano M, Haraguchi Y, Sayano T, Zyao C, Arimoto Y, Kawano Y, Moriyasu K, Udono M, Katakura Y, Ogawa T, Kato H, Furuya S.   +11 more
europepmc   +1 more source

Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors. [PDF]

Bioorg Med Chem, 2018
Rohde JM, Brimacombe KR, Liu L, Pacold ME, Yasgar A, Cheff DM, Lee TD, Rai G, Baljinnyam B, Li Z, Simeonov A, Hall MD, Shen M, Sabatini DM, Boxer MB.   +14 more
europepmc   +1 more source

Stability & Flexibility of 3‐Phosphoglycerate Dehydrogenase

The FASEB Journal, 2006
Thai Vo, Christina Cochoran, Chateece Chappell, Olu Taylor, Ellis Bell   +4 more
openaire   +1 more source

Phosphoglycerate dehydrogenase is a novel predictor for poor prognosis in gastric cancer. [PDF]

Onco Targets Ther, 2016
Xian Y, Zhang S, Wang X, Qin J, Wang W, Wu H.   +5 more
europepmc   +1 more source

α-Ketothioamide Derivatives: A Promising Tool to Interrogate Phosphoglycerate Dehydrogenase (PHGDH). [PDF]

J Med Chem, 2017
Ravez S, Corbet C, Spillier Q, Dutu A, Robin AD, Mullarky E, Cantley LC, Feron O, Frédérick R.   +8 more
europepmc   +1 more source

Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase. [PDF]

Theranostics, 2018
Dong JK, Lei HM, Liang Q, Tang YB, Zhou Y, Wang Y, Zhang S, Li WB, Tong Y, Zhuang G, Zhang L, Chen HZ, Zhu L, Shen Y.   +13 more
europepmc   +1 more source

Structural insights into the enzymatic activity and potential substrate promiscuity of human 3-phosphoglycerate dehydrogenase (PHGDH). [PDF]

Oncotarget, 2017
Unterlass JE, Wood RJ, Baslé A, Tucker J, Cano C, Noble MME, Curtin NJ.   +6 more
europepmc   +1 more source

Phosphoglycerate dehydrogenase inhibition induces p-mTOR-independent autophagy and promotes multilineage differentiation in embryonal carcinoma stem-like cells. [PDF]

Cell Death Dis, 2018
Sharif T, Martell E, Dai C, Ghassemi-Rad MS, Lee K, Singh SK, Weaver ICG, Gujar S.   +7 more
europepmc   +1 more source

1p/19q codeletion induces targetable and imageable vulnerabilities in glucose metabolism in oligodendrogliomas. [PDF]

Neuro Oncol
Udutha S, Batsios G, Taglang C, Gillespie AM, Viswanath P.   +4 more
europepmc   +1 more source

Serine Ameliorates Cadmium-Induced Testicular Injury by Regulating the PGAM1/PHGDH Signaling Pathway. [PDF]

J Biochem Mol Toxicol
Wang X, Luo N, Ma Y, Zou H, Tong X, Zhu J, Song R, Zhao H, Liu Z.   +8 more
europepmc   +1 more source