Results 151 to 160 of about 182,707 (224)

3-phosphoglycerate dehydrogenase as target in cancer therapy [PDF]

, 2016
PhD ThesisCancer cells adapt their metabolism to simultaneously fulfil the requirements of energy production and biomass generation necessary to sustain high proliferation rates.
Unterlass, Judith Edda.
core  

Structural Analysis of Substrate and Effector Binding in Mycobacterium tuberculosis d-3-Phosphoglycerate Dehydrogenase

, 2016
The crystal structure of Mycobacterium tuberculosis d-3-phosphoglycerate dehydrogenase has been solved with bound effector, l-serine, and substrate, hydroxypyruvic acid phosphate, at resolutions of 2.7 and 2.4 Å, respectively.
Gregory A. Grant (1540906), Sanghamitra Dey (2425774), Rodney L. Burton (2329372), James C. Sacchettini (37661)   +3 more
core   +1 more source

Precision Nutrition as the Concept of Dietary and Nutritional Interventions for Patients With Malignancies: A Narrative Literature Review and Perspectives

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Dietary and nutritional interventions have gained popularity among patients with cancer undergoing treatment due to the high cost of medical treatment and increased health awareness. Diet, nutrition, psychological stress, and adverse events during treatment have a significant impact on the quality of life of patients with cancer ...
Ken Yamaguchi, Koji Yamanoi, Jumpei Ogura, Ayami Koike, Maki Umemiya, Nozomi Higashiyama, Kazuhiro Kou, Yoshihide Inayama, Rin Mizuno, Taito Miyamoto, Mana Taki, Ryusuka Murakami, Junzo Hamanishi, Mandai Masaki   +13 more
wiley   +1 more source

Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine. [PDF]

J Clin Invest, 2021
Zhang Y, Yu H, Zhang J, Gao H, Wang S, Li S, Wei P, Liang J, Yu G, Wang X, Li X, Li D, Yang W.   +12 more
europepmc   +1 more source

Lactate metabolism and protein lactylation in programmed cell death: From novel mechanism to therapeutic strategies in human diseases

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
This review highlights protein lactylation as a metabolic‐epigenetic regulator linking lactate reprogramming to programmed cell death. By modulating histone and non‐histone targets, lactylation reshapes cell fate decisions and represents a promising biomarker and therapeutic target in human diseases.
Yue Chen, Xiwen Wang, Xiuping Wang, Na Lin, Wenjie Wang, Ruiqi Fu, Yutong Wu, Yi Liu, Hengwei Liu   +8 more
wiley   +1 more source

Diversified amino acid-mediated allosteric regulation of phosphoglycerate dehydrogenase for serine biosynthesis in land plants. [PDF]

Biochem J, 2021
Okamura E, Ohtaka K, Nishihama R, Uchida K, Kuwahara A, Mochida K, Hirai MY.   +6 more
europepmc   +1 more source

A Review on Carbon Sequestration Techniques From Geological to Biological Methods: Mechanisms, Methods, and Future Perspectives

Engineering Reports, Volume 8, Issue 10, October 2026.
This study reviews CO2 storage methods: geological (depleted reservoirs, saline aquifers, salt caverns, basalt), oceanic (dissolution, hydrates, phytoplankton), and biological (microalgae like Chlorella and Spirulina with 10–50× higher capture than plants; MICP by Sporosarcina pasteurii).
Mohmmadreza Alipour, Masoud Shafiei, Mohammadkazem Amiri, Ehsan Nikooee   +3 more
wiley   +1 more source

The effect of paramagnetic center of 2.03 average g-value on D-glyceraldehyde-3-phosphate dehydrogenase

, 1971
Pairwise coupled reactions of fructose-1,6-bisphosphate aldolase and sn-glycerol-3-phosphate dehydrogenase, 3-phosphoglycerate kinase and D-glyceraldehyde-3-phosphate dehydrogenase,triosephosphate isomerase and sn-glycerol- 3-phosphate dehydrogenase have
Keleti, Tamás, Elek, G
core  

Erratum: Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase: Erratum. [PDF]

Theranostics, 2021
Dong JK, Lei HM, Liang Q, Tang YB, Zhou Y, Wang Y, Zhang S, Li WB, Tong Y, Zhuang G, Zhang L, Chen HZ, Zhu L, Shen Y.   +13 more
europepmc   +1 more source

The Sleeping Giant: Metabolism and Autophagy in the Generation and Survival of Dormant Polyploid Giant Cancer Cells

MedComm, Volume 7, Issue 10, October 2026.
Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna, María Teresa Sánchez‐Montero, Alejandra Díaz‐Chacón, Antonio Rodríguez‐Ariza   +3 more
wiley   +1 more source