Results 151 to 160 of about 375,644 (216)

How Plants May Maintain Protein Homeostasis Under Rising Atmospheric CO2

Plant, Cell &Environment, Volume 49, Issue 5, Page 2654-2672, May 2026.
ABSTRACT Vascular plants may employ several physiological mechanisms to stabilize their protein contents as atmospheric CO2 concentrations change over a day, year, decade, or century. One mechanism is that plants may rely more on soil ammonium as their nitrogen source when CO2 increases.
Arnold J. Bloom, Xiaoxiao Shi, Nathan M. Hannon   +2 more
wiley   +1 more source

Proteomics-Based RT-qPCR and Functional Analysis of 18 Genes in Metronidazole Resistance of Bacteroides fragilis

Antibiotics
Previously, we reported that metronidazole MICs are not dependent on the expression levels of nim genes in B. fragilis strains and we compared the proteomes of metronidazole-resistant laboratory B.
Bakhtiyar Mahmood, Ana Paunkov, Malgorzata Kupc, Katalin Burián, Elisabeth Nagy, David Leitsch, József Sóki   +6 more
doaj   +1 more source

Phosphoglycerate dehydrogenase (PHGDH) [PDF]

Science-Business eXchange, 2011
openaire   +3 more sources

Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis. [PDF]

, 2019
Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic disruption that may be therapeutically targetable. Among them, glucose metabolism and glycolytic intermediaries seem to have an important role in fibroblast-like ...
de Oliveira, Patricia Gnieslaw, Farinon, Mirian, Guma, Monica, Miyamoto, Shigeki, Sanchez-Lopez, Elsa   +4 more
core   +1 more source

3-phosphoglycerate dehydrogenase deficiency: a case report of a treatable cause of seizures

The Turkish Journal of Pediatrics, 2009
Serine deficiency disorders are a new group of neurometabolic diseases resulting from a deficiency in one of the three enzymes in the biosynthetic pathway of L-serine.
Turgay Coşkun, Halil Ibrahim Aydin, Mustafa Kiliç, Ali Dursun, Göknur Haliloğlu, Haluk Topaloğlu, Kader Karli-Oğuz, Tom J De Koning   +7 more
doaj  

Recent progress in serine metabolism reprogramming in tumors and strategies for serine deprivation

Frontiers in Oncology
Tumor cells undergo extensive metabolic reprogramming during malignant proliferation, with serine—a key nonessential amino acid—playing multiple roles in tumor metabolism.
Huimei Liu, Huimei Liu, Yanping Liu
doaj   +1 more source

Metabolic remodeling and immune evasion in glioblastoma: a focus on serine and lipid networks

Frontiers in Oncology
Glioblastoma (GBM) is a highly aggressive brain tumor characterized by metabolic plasticity that fuels growth, therapy resistance, and immune evasion. Among its reprogrammed pathways, serine and lipid metabolism play central roles.
Dongxin Jiang, Chuheng Wang, Yao Zhao, Yunqian Li   +3 more
doaj   +1 more source

Serine Metabolism Regulates the Replicative Senescence of Human Dental Pulp Cells through Histone Methylation

Current Issues in Molecular Biology
Tissue regeneration therapy based on human dental pulp cells (hDPCs) faces the distinct challenge of cellular senescence during massive expansion in vitro.
Shuhan Zhou, Jingyao Cui, Yu Shi
doaj   +1 more source

Global Metabolic Shifts in Age and Alzheimer's Disease Mouse Brains Pivot at NAD+/NADH Redox Sites. [PDF]

, 2019
Age and Alzheimer's disease (AD) share some common features such as cognitive impairments, memory loss, metabolic disturbances, bioenergetic deficits, and inflammation.
Brewer, Gregory J, Dong, Yue
core  

Diversified amino acid-mediated allosteric regulation of phosphoglycerate dehydrogenase for serine biosynthesis in land plants. [PDF]

Biochem J, 2021
Okamura E, Ohtaka K, Nishihama R, Uchida K, Kuwahara A, Mochida K, Hirai MY.   +6 more
europepmc   +1 more source