Results 161 to 170 of about 182,707 (224)

The construction of a genome‐wide transposon library of Glaesserella parasuis and its use to identify genes essential for in vitro and in vivo survival

mLife, Volume 5, Issue 5, Page 626-636, October 2026.
Abstract Glaesserella parasuis is an important porcine pathogen that commonly colonizes the upper respiratory tract of pigs and is the etiological agent of Glässer's disease, causing substantial economic losses in the global swine industry. This study aimed to identify genes essential for both in vitro growth and in vivo pathogenicity of G.
Xiaowei Gong, Yuqian Shi, Liuqing He, Qingpo Cui, Guanzheng Zhao, Shuo Xu, Luyu Ying, Qin Yang, Xiaoxia Qin, Tong Sun, Xiaotong Jiang, Juanjuan Wang, Zhangqi Shen, Mengjiao Fu   +13 more
wiley   +1 more source

Identification of Molecular Pathways Underlying Mn(II) Oxidation in Pseudomonas resinovorans

Environmental Microbiology, Volume 28, Issue 10, October 2026.
Transposon mutagenesis in biofilter‐associated Pseudomonas resinovorans MOB‐513 identifies a c‐di‐GMP‐dependent regulatory network involving type IV pili, two‐component systems, and diguanylate cyclases that controls Mn(II) oxidation and biofilm formation, providing new insight into microbial manganese cycling and biofilter performance.
Ainelén Piazza, Lucia Parra, Marilina Gaffuri, Jacob G. Malone, Jorgelina Ottado, Natalia Gottig   +5 more
wiley   +1 more source

D-3-Phosphoglycerate Dehydrogenase [PDF]

, 2020
openaire   +1 more source

PHGDH mediated serine biosynthesis metabolism suppresses vascular calcification

Biology Direct
Background Vascular calcification is a major pathological process driving cardiovascular morbidity and mortality, yet effective therapies are lacking.
Liao Tan, Jie Liu, Ruizheng Shi, Yubo Liu   +3 more
doaj   +1 more source

Adaptive Laboratory Evolution Rewires Pseudomonas putida for Resource‐Efficient Acetate Assimilation

Microbial Biotechnology, Volume 19, Issue 10, October 2026.
Adaptive laboratory evolution selected key mutations that improved acetate tolerance in genome‐reduced Pseudomonas putida. Multi‐omic analyses showed that adaptation increased biomass yield by reallocating resources away from costly stress‐associated programs and redirecting acetate carbon toward carbon‐conserving metabolism.
Nicolás Gurdo, Aparajitha Srinivasan, Tommaso Tagliani, Melanie Filbig, Nicolas T. Wirth, Josefin Johnsen, Garret W. O'Connell, Stefano Donati, Enrico Orsi, María V. G. Alván‐Vargas, Yan Chen, Christopher J. Petzold, Matthew Blow, Thomas Eng, Till Tiso, Lars M. Blank, Adam Feist, Aindrila Mukhopadhyay, Pablo I. Nikel   +18 more
wiley   +1 more source

Comparative Transcriptomic Analysis of In Vitro Matured Oocytes From Cyclic and Prepubertal Gilts Reveals Distinct Molecular Patterns

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT In vitro embryo production is a key tool in reproductive biotechnology, enabling genetic improvement, basic research on early development, and the generation of biomedical models. Despite high rates of nuclear maturation achieved during in vitro maturation (IVM) of porcine oocytes, inadequate cytoplasmic maturation continues to limit oocyte ...
Carolina G. Cabrera‐Gómez, David Gascón‐Collado, Paula Blanco‐Cueto, Belén Pequeño, Heriberto Rodríguez‐Martínez, Cristina A. Martínez‐Serrano   +5 more
wiley   +1 more source

Exercise training does not mitigate high‐phosphate diet‐induced mitochondrial dysfunction in skeletal muscle in male mice

Physiological Reports, Volume 14, Issue 20, October 2026.
Abstract Inorganic phosphate consumption in adults is two‐to‐three‐fold higher than the recommended daily allowance due to its widespread use as a preservative and flavor enhancer in processed foods. We previously reported that 12 weeks of high‐phosphate diet (HPD) reduced VO2max and altered metabolic gene expression and mitochondrial dysfunction in ...
Hannah F. Sanders, Dominic W. Kolonay, Jade A. Blackwell, Jiaru Liu, Isabella R. Dobrski, Daniel A. Branch, Lucas A. Lefers, Benjamen H. Kern, Kedryn K. Baskin   +8 more
wiley   +1 more source

Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma. [PDF]

Cell Rep, 2021
Rathore R, Caldwell KE, Schutt C, Brashears CB, Prudner BC, Ehrhardt WR, Leung CH, Lin H, Daw NC, Beird HC, Giles A, Wang WL, Lazar AJ, Chrisinger JSA, Livingston JA, Van Tine BA.   +15 more
europepmc   +1 more source

Post-translational regulation of human D-3-phosphoglycerate dehydrogenase in Alzheimer's disease. [PDF]

Protein Sci
Zerbini E, Riva D, Maffioli E, Tedeschi G, Sacchi S, Pollegioni L.   +5 more
europepmc   +1 more source

Exercise Reprograms the Spatial Function of Phosphoglycerate Dehydrogenase of a Pathogenic Nuclear Transcription Factor (PHGDH): A Narrative Review. [PDF]

Metabolites
Yang D, Guo W, Guo L.
europepmc   +1 more source