Results 141 to 150 of about 182,707 (224)

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, Volume 16, Issue 10, Page 1911-1924, October 2026.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Glycolysis pathway reconstructed based on the de novo assembly and annotation of E. cf. polyphem transcriptome.

, 2012
Identified enzymes are shown in boxes and include: HK, hexokinase (EC:2.7.1.1); GCK, glucokinase (EC: 2.7.1.2); G6PI, glucose-6-phosphate isomerase (EC: 5.3.1.9); PFK, phosphofructokinase-6 (EC: 2.7.1.11); FBA, fructose-bisphosphate aldolase (EC:4.1.2.13)
Juan Han (169478), ShunJi Yin (169505), Min Sang (169486), AiFen Li (169494), LingLin Wan (169470), Hong Wu (105254), ChengWu Zhang (169509)   +6 more
core   +1 more source

Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism. [PDF]

EMBO J, 2022
Shu Y, Hao Y, Feng J, Liu H, Li ST, Feng J, Jiang Z, Ye L, Zhou Y, Sun Y, Zhou Z, Wei H, Gao P, Zhang H, Sun L.   +14 more
europepmc   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, Volume 13, Issue 59, 23 October 2026.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Pathways of glucose and glycerol metabolism in L. reuteri DSM20016.

, 2016
A) The proposed routes for glucose metabolism using Embden- Meyerhof (EMP) and -phosphoketolase (PKP) pathways, and model of the Pdu microcompartment and -pathway for glycerol transformation.
Paul David Bromberger (3605345), Rajni Hatti-Kaul (568733), Gavin Nieuwenhuiys (3605348), Lu Chen (75170)   +3 more
core   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Serine Metabolism Regulates the Replicative Senescence of Human Dental Pulp Cells through Histone Methylation

Current Issues in Molecular Biology
Tissue regeneration therapy based on human dental pulp cells (hDPCs) faces the distinct challenge of cellular senescence during massive expansion in vitro.
Shuhan Zhou, Jingyao Cui, Yu Shi
doaj   +1 more source

Metal–Organic Frameworks for CO2 Conversion: From Simple Capture Materials to Multiple Function Platforms

Aggregate, Volume 7, Issue 10, October 2026.
This review summarizes recent advances in MOFs for CO2 valorization, covering MOF synthesis, CO2 capture, and photo/electrocatalytic CO2 reduction. Detailed discussion of typical strategies reveals the intrinsic structure–performance relationship, and challenges together with future perspectives are proposed.
Yingjia Li, Zhaoyuan Feng, Meiyu Zhang, Manman Shi, Lixue Zhao, Yuxiao Feng, Xing Zhang, Jiandong Cui   +7 more
wiley   +1 more source

DEGs involved in glycolysis in M5 samples compared with C samples.

, 2016
5.4.2.2, phosphoglucomutase; 2.7.1.1, hexokinase; 5.1.3.15, glucose-6-phosphate 1-epimerase; 4.1.2.13, fructose-bisphosphate aldolase; 5.3.1.1, triosephosphate isomerase; 1.2.1.12, glyceraldehyde 3-phosphate dehydrogenase; 2.7.2.3, phosphoglycerate ...
Zhezhi Wang (148281), Xinbing Yang (3350177), Wenping Hua (148276), Jiefang Kang (3350180), Xiaorong Guo (3350186), Huaiqin Wang (3350183), Yihan He (3350174), Xiaoyan Cao (272661)   +7 more
core   +1 more source

Metabolic Flux Analysis Reveals Cell Line‐Specific Rewiring in CHO Cells Following TCA Cycle Intermediate Feeding for Bioprocess pH Control

Biotechnology and Bioengineering, Volume 123, Issue 10, Page 2713-2728, October 2026.
ABSTRACT Chinese hamster ovary (CHO) cells are the leading host for recombinant therapeutic protein production in the biopharma industry. In this study, we investigated how feeding acidic forms of tricarboxylic acid (TCA) cycle intermediates—malic acid, succinic acid, and α‐ketoglutaric acid—affects cell culture performance and metabolism in two ...
Sarah A. Sacco, Kevin J. Ruiz‐Márquez, Rachel Moen, Irina Trenary, Xiaolin Zhang, Xiaowen Wang, Malik Padellan, Henry Lin, Jamey D. Young   +8 more
wiley   +1 more source