Results 211 to 220 of about 37,565 (330)

Molecular insight on the role of the phosphoinositide PIP3 in regulating the protein kinases Akt, PDK1, and BTK. [PDF]

Biochem Soc Trans
Shaw AL, Burke JE.
europepmc   +1 more source

Elevated levels of IL-1β in Fanconi anaemia group A patients due to a constitutively active phosphoinositide 3-kinase-Akt pathway are capable of promoting tumour cell proliferation [PDF]

, 2009
Ana Ibáñez, Paula Rı́o, José Antonio Casado, Juan A. Bueren, José L. Fernández-Luna, Carlos Pipaón   +5 more
openalex   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

British Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

Lack of myotubularin phosphatase activity is the main cause of X-linked myotubular myopathy. [PDF]

JCI Insight
Moschovaki-Filippidou F, Kretz C, Reiss D, Chicanne G, Payrastre B, Laporte J.   +5 more
europepmc   +1 more source

Different Subcellular Localization and Phosphoinositides Binding of Insulin Receptor Substrate Protein Pleckstrin Homology Domains [PDF]

, 2000
Giorgia Razzini, Alessandra Ingrosso, Anna Brancaccio, Salvatore Sciacchitano, Diana L. Esposito, Marco Falasca   +5 more
openalex   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Inositol and PIP2/PIP3 Ratio: At the Crossroad of the Biodynamic Interface Between Cells and Their Microenvironment. [PDF]

Biomolecules
Lentini G, Querqui A, Giuliani A, Verna R, Bizzarri M.   +4 more
europepmc   +1 more source

Isoproterenol modulates insulin activation of insulin receptor kinase in intact rat adipocytes [PDF]

, 1988
Klein, H. H., Matthaei, S., Scriba, Peter Christian   +2 more
core  

Table S3 from Co-targeting Phosphoinositide 3-Kinase and Focal Adhesion Kinase Pathways Inhibits Proliferation of NF2 Schwannoma Cells

Haley M. Hardin, Christine T. Dinh, Julianne Huegel, Alejandra M. Petrilli, Olena Bracho, Abdulrahman Allaf, Matthias A. Karajannis, Anthony J. Griswold, Michael E. Ivan, Jacques J. Morcos, Sakir H. Gultekin, Fred F. Telischi, Xue Zhong Liu, Cristina Fernández‐Valle   +13 more
openalex   +1 more source

A Phosphoinositide Binding Module Controls TMEM16A Desensitization [PDF]

, 2019
Son C. Le, Zhiguang Jia, Jianhan Chen, Huanghe Yang   +3 more
openalex   +1 more source