Results 231 to 240 of about 13,157 (254)
Some of the next articles are maybe not open access.
Phosphoinositides and Cellular Pathogens
2012Phosphoinositides are considered as highly dynamic players in the spatiotemporal organization of key signaling pathways, actin cytoskeleton rearrangements, establishment of cell polarity and intracellular vesicle trafficking. Their metabolism is accurately controlled and mutations in several phosphoinositide metabolizing enzymes take part in the ...
Payrastre, Bernard +3 more
openaire +2 more sources
Phosphoinositides and cell proliferation
Journal of Cell Science, 1985ABSTRACT Certain growth factors act by stimulating the hydrolysis of inositol lipids to yield putative second messengers such as diacylglycerol (DG) and inositol trisphosphate (IP3). One function of the former is to stimulate C-kinase, which may act by switching on a sodium/hydrogen exchanger to induce the increase in pH that appears to ...
M J, Berridge +3 more
openaire +2 more sources
Phosphoinositide Recognition Domains
Traffic, 2003Domains or modules known to bind phosphoinositides have increased dramatically in number over the past few years, and are found in proteins involved in intracellular trafficking, cellular signaling, and cytoskeletal remodeling. Analysis of lipid binding by these domains and its structural basis has provided significant insight into the mechanism of ...
openaire +2 more sources
Phosphoinositide-Regulated Kinases and Phosphoinositide Phosphatases
Chemical Reviews, 2001N R, Leslie, R M, Biondi, D R, Alessi
openaire +2 more sources
Nuclear Phosphoinositides and Their Functions
2004Phosphoinositides are minor components of biological membranes, which have emerged as essential regulators of a variety of cellular processes, both on the plasma membrane and on several intracellular organelles. The versatility of these lipids stems from their ability to function either as substrates for the generation of second messengers, as membrane-
G, Hammond, C L, Thomas, G, Schiavo
openaire +2 more sources
Phosphoinositides and Synaptic Transmission
1996The isolation of a “diphosphoinositide” fraction from ox brain by Folch (1949) and the observation by Dawson (1954) that radioactive phosphate was rapidly incorporated into its lipids laid the foundations of our present knowledge of the brain phosphoinositides.
openaire +2 more sources