p75NTR Promotes Circadian‐Driven Mineralization During Tooth Development via CK2/PER2 Pathway
The diagram illustrates how the circadian rhythm regulates the p75NTR‐CK2‐PER2 axis, driving rhythmic biomineralisation during tooth development. ABSTRACT Circadian rhythm is an essential biological process that synchronises physiological activities with environmental light/dark cycles.
Manzhu Zhao +8 more
wiley +1 more source
Correction: Phosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinase. [PDF]
europepmc +1 more source
Unraveling the role of amphisomes in mast cell secretory granule fusion and exosome release. [PDF]
Tsilioni I.
europepmc +1 more source
Transglutaminase‐mediated cytokeratin modifications implicated in bile‐acid‐induced hepatocyte death
Cholestasis and bile‐acid exposure enhance expression and activity of protein crosslinking enzymes TG1 and TG2 in hepatocytes. Substrate proteins were identified by mass spectrometry using biotin‐labeled peptides (pepK5/pepT26) or amine donor (biotinylated pentylamine; BPA). Crosslinking‐induced aggregation and fragmentation of keratin 18 and 8 (K18/K8)
Hideki Tatsukawa +4 more
wiley +1 more source
A cell-permeable fluorescent probe reveals temporally diverse PI(4,5)P2 dynamics evoked by distinct GPCR agonists in neurons. [PDF]
Kundu R +9 more
europepmc +1 more source
Evaluation of Lymphoproliferative Disease and Increased Risk of Lymphoma in Activated Phosphoinositide 3 Kinase Delta Syndrome: A Case Report With Discussion [PDF]
Michele N. Pham +1 more
openalex +1 more source
Sensing of cardiolipin exposure on plasma membranes of apoptotic cells by EryA‐mCherry protein
An aegerolysin protein erylysin A (EryA) fused with mCherry binds to artificial lipid vesicles supplemented with cardiolipin (CL). This binding is much more specific than that of annexin V, which binds various negatively charged glycerophospholipids (PG, PS, PI). In mammalian cells, the CL exposition at the membrane surface represents an early hallmark
Luka Žeželj +12 more
wiley +1 more source
The Influence of Phosphoinositide Lipids in the Molecular Biology of Membrane Proteins: Recent Insights from Simulations. [PDF]
Hedger G, Yen HY.
europepmc +1 more source

