Genetic variants underlying precancerous conditions of hepatocellular carcinoma
Abstract Hepatocellular carcinoma (HCC) is the most common form of liver cancer, accounting for 80% of cases worldwide. While chronic hepatitis B and C infections remain primary risk factors, emerging evidence highlights the increasing contributions of metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease
Jonathan Jaime G. Guerrero+7 more
wiley +1 more source
Release of carcinoembryonic antigen from human colon cancer cells by phosphatidylinositol-specific phospholipase C. [PDF]
Todd L. Sack+3 more
openalex +1 more source
Genomic Insights into the Phosphatidylinositol-Specific Phospholipase C Gene Family in <i>Leishmania major</i> and <i>Leishmania infantum</i>: Expression Patterns and Potential Association with Drug Resistance. [PDF]
Sirekbasan S, Osman SS, Gürkök-Tan T.
europepmc +1 more source
Global analysis of putative phospholipases in Plasmodium falciparum reveals an essential role of the phosphoinositide-specific phospholipase C in parasite maturation. [PDF]
Burda PC+12 more
europepmc +1 more source
Regulation of inositol phospholipid-specific phospholipase C isozymes.
S. Rhee, Kang Duk Choi
semanticscholar +1 more source
Abstract Background Coronavirus disease 2019 (COVID‐19) is a complicated disease with widely varying outcomes. Up to 20% of unvaccinated, hospitalized patients infected with COVID‐19 may die during the initial three weeks. Our research shows that COVID‐19 infection results in rapid, remarkable change in the balance between essential fatty acid ...
Vera C. Mazurak+8 more
wiley +1 more source
Polyamines inhibit phospholipase C-catalysed polyphosphoinositide hydrolysis. Studies with permeabilized GH3 cells [PDF]
Richard J.H. Wojcikiewicz, John N. Fain
openalex +1 more source
Phospholipase C-β3 is dispensable for vascular constriction but indispensable for vascular hyperplasia. [PDF]
Jin SY+11 more
europepmc +1 more source