Results 21 to 30 of about 255,660 (330)

Successful Production of Offspring Derived from Phospholipase C Zeta-Deficient Sperm by Additional Artificial Activation

open access: yesLife, 2023
During mammalian fertilization, repetitive rises of intracellular calcium called calcium oscillations are required for full activation of oocytes. Therefore, oocytes such as round spermatid injected or somatic cell nuclear transferred require additional ...
Naoki Hirose   +9 more
doaj   +1 more source

磷脂酶Lecitase Ultra和磷脂酶C复合 对冷榨菜籽油脱胶的影响Enzymatic degumming of cold pressed rapeseed oil with phospholipase Lecitase Ultra and phospholipase C

open access: yesZhongguo youzhi, 2022
为了提高脱胶效率,以冷榨菜籽原油为原料,磷脂含量为指标,采用磷脂酶Lecitase Ultra和磷脂酶C复合酶法对冷榨菜籽油进行脱胶。采用单因素试验考察磷脂酶Lecitase Ultra反应时间、磷脂酶C反应时间、加水量、磷脂酶Lecitase Ultra添加量、磷脂酶C添加量、柠檬酸溶液添加量对脱胶油磷脂含量的影响,并通过响应面法优化脱胶条件。对优化的脱胶条件下所得到的脱胶油的理化指标进行了检测,并与国标一级压榨菜籽油进行了比较。结果表明:磷脂酶Lecitase ...
马云睿1,周力1,高盼1,2,胡传荣1,2,罗质1,2,何东平1,2MA Yunrui1, ZHOU Li1, GAO Pan1,2, HU Chuanrong1,2, LUO Zhi1,2, HE Dongping1,2
doaj   +1 more source

Phospholipase C [PDF]

open access: yes, 2019
Phospholipase C (PLC) family members constitute a family of diverse enzymes. Thirteen different family members have been cloned. These family members have unique structures that mediate various functions. Although PLC family members all appear to signal through the bi-products of cleaving phospholipids, it is clear that each family member, and at times
Colin A, Bill, Charlotte M, Vines
openaire   +2 more sources

Cellular cholesterol efflux is modulated by phospholipid-derived signaling molecules in familial HDL deficiency/Tangier disease fibroblasts

open access: yesJournal of Lipid Research, 2001
Familial HDL deficiency (FHD) is the heterozygous form of Tangier disease (TD). Mutations of the ABCA1 gene cause FHD and TD. FHD/TD cells are unable to normally efflux cholesterol onto nascent HDL particles, which are rapidly catabolized. TD fibroblasts
Bassam Haidar   +5 more
doaj   +1 more source

Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain

open access: yesMolecules, 2022
Phospholipase is an enzyme that hydrolyzes various phospholipid substrates at specific ester bonds and plays important roles such as membrane remodeling, as digestive enzymes, and the regulation of cellular mechanism.
Yunseok Heo   +8 more
doaj   +1 more source

Current data on the effectiveness of gliclazide and molecular mechanisms of action of the drug

open access: yesСахарный диабет, 2020
With the growing prevalence of type 2 diabetes mellitus (T2DM) the possibility of treating it with available drugs is one of the main issues. Although glycemic control and reduction of micro- and macrovascular outcomes remain important aspects of ...
Nina A. Petunina   +2 more
doaj   +1 more source

Phospholipase C isozymes as effectors of Ras superfamily GTPases

open access: yesJournal of Lipid Research, 2009
The physiological effects of many extracellular stimuli are initiated through receptor-promoted activation of phospholipase C and inositol lipid signaling pathways.
T. Kendall Harden   +2 more
doaj   +1 more source

Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis

open access: yesJournal of Lipid Research, 2008
Critical developmental periods, such as fertilization, involve metabolic activation, membrane fusion events such as sperm-egg or plasma membrane-cortical granule merger, and production and hydrolysis of phospholipids.
Douglas W. Petcoff   +2 more
doaj   +1 more source

Secretory Phospholipases A2 in Plants [PDF]

open access: yes, 2019
Secreted phospholipases (sPLA2s) in plants are a growing group of enzymes that catalyze the hydrolysis of sn-2 glycerophospholipids to lysophospholipids and free fatty acids. Until today, around only 20 sPLA2s were reported from plants.
Fidelio, Gerardo Daniel   +1 more
core   +1 more source

Activation of phospholipase D-2 by P2X7 agonists in rat submandibular gland acini

open access: yesJournal of Lipid Research, 2002
Exogenous ATP stimulated phospholipase D (PLD), but not sphingomyelinase in rat submandibular gland (SMG) acini. PLD activation was dependent upon extracellular Ca2+ and did not involve intracellular Ca2+ mobilization or phosphoinositide-specific ...
Encarnación Pérez-Andrés   +11 more
doaj   +1 more source

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