Results 21 to 30 of about 19,636,220 (230)
Current data on the effectiveness of gliclazide and molecular mechanisms of action of the drug
Сахарный диабет, 2020 With the growing prevalence of type 2 diabetes mellitus (T2DM) the possibility of treating it with available drugs is one of the main issues. Although glycemic control and reduction of micro- and macrovascular outcomes remain important aspects of ...
Nina A. Petunina +2 more
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Isolation, Characterization, and Biological Activity of Phospholipase A2 (PLA2) and Hyaluronidase from Iranian Honey Bee Venom (Apis Mellifera meda) [PDF]
مجله بیوتکنولوژی کشاورزی, 2023 ObjectiveBee venom contains various enzymes such as hyaluronidase and phospholipase A2, which have medical and pharmaceutical applications. In several studies, the activity of phospholipase A2 and hyaluronidase has been reported in different bee species,
Mahmood Nazari +2 more
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PLoS Genetics, 2015 Phosphoinositides represent important lipid signals in the plant development and stress response. However, multiple isoforms of the phosphoinositide biosynthetic genes hamper our understanding of the pivotal enzymes in each step of the pathway as well as
K. Kanehara +7 more
semanticscholar +1 more source
Bacterial phospholipases C [PDF]
Microbiological Reviews, 1993 A variety of pathogenic bacteria produce phospholipases C, and since the discovery in 1944 that a bacterial toxin (Clostridium perfringens alpha-toxin) possessed an enzymatic activity, there has been considerable interest in this class of proteins. Initial speculation that all phospholipases C would have lethal properties has not been substantiated ...
openaire +2 more sources
Pathogens, 2019 In order to survive as extracellular parasites in the mammalian host environment, Trypanosoma brucei has developed efficient mechanisms of immune system evasion, which include the abundant expression of a variable surface glycoprotein (VSG) coat.
Cláudia Jassica Gonçalves Moreno +2 more
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Structural Insights into Phospholipase C-β Function
Molecular Pharmacology, 2013 Phospholipase C (PLC) enzymes convert phosphatidylinositol-4,5-bisphosphate into the second messengers diacylglycerol and inositol-1,4,5-triphosphate.
A. Lyon, J. Tesmer
semanticscholar +1 more source
Regulation of Phosphoinositide-specific Phospholipase C Isozymes*
Journal of Biological Chemistry, 1997 The hydrolysis of a minor membrane phospholipid, phosphatidylinositol 4,5-bisphosphate (PIP2), 1 by a specific phospholipase C (PLC) is one of the earliest key events in the regulation of various cell functions by more than 100 extracellular signaling ...
S. Rhee, Y. Bae
semanticscholar +1 more source
Balkan Journal of Medical Genetics, 2018 Human hereditary leukonychia is a rare nail disorder characterized by nail plates whitening on all finger and toe nails. Inheritance pattern is both autosomal dominant and recessive. To date, the only gene, phospholipase C, δ1 (PLCD1), on chromosome 3p22.
Khan AK +8 more
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Zhongguo shipin weisheng zazhiObjectiveTo provide a genetic basis for scientific prevention and control of food poisoning caused by Bacillus cereus， the pathogenic characteristics of foodborne Bacillus cereus strains isolated in Yueyang City Hu’nan Province from 2014 to 2019 were ...
XIE Weian +5 more
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Biologia Plantarum, 2011 It has been suggested in Arabidopsis thaliana (L.) Heynh. cv. Columbia that, contrary to 30 μM abscisic acid (ABA), 20 μM ABA induces guard cell Ca2+ mobilization through activating phosphoinositide-specific phospholipase C (PI-PLC)-dependent inositol 1 ...
A. Cousson
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