ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
British Journal of Pharmacology, EarlyView.G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison +15 more
wiley +1 more source
Spectrophotometric determination of lipases, lysophospholipases, and phospholipases
Journal of Lipid Research, 1984 Spectrophotometric techniques for determining the activities of lipases, lysophospholipases, and phospholipases are reviewed. These methods involve the use of thioester substrate analogs as well as omega-nitrophenyl derivatives of the corresponding ...
A A Farooqui +4 more
doaj
Secretory Phospholipases A2, from Snakebite Envenoming to a Myriad of Inflammation Associated Human Diseases-What Is the Secret of Their Activity? [PDF]
Int J Mol Sci, 2023 Tonello F.
europepmc +1 more source
Phase Transitions in Systems of Interacting Species [PDF]
arXiv, 2014 We discuss an autocatalytic reaction system: the cyclic competition model A1 + A2 --> 2 A2, A2 + A3 --> 2 A3, A3 + A4 --> 2 A4, A4 + A1 --> 2 A1), as well as its neutral counterpart. Migrations are introduced into the model. When stochastic phenomena are taken into account, a phase transition between a ``fixation'' and a ``neutral'' regime is observed.
arxiv
Effects of bivalent cations on prostaglandin biosynthesis and phospholipase A2 activation in rabbit kidney medulla slices [PDF]
, 1979 A. Erman, A Raz
openalex +1 more source
Progress on the development of Class A GPCR‐biased ligands
British Journal of Pharmacology, EarlyView.Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales +20 more
wiley +1 more source
Journal of Lipid Research, 2015 PPARα is well known as a master regulator of lipid metabolism. PPARα activation enhances fatty acid oxidation and decreases the levels of circulating and cellular lipids in obese diabetic patients.
Haruya Takahashi +10 more
doaj
Journal of Acute Disease, 2015 Objective: To study the inhibitory activity of ethanolic extract from Mimosa pigra and Ipomoea asarifolia against Trypanosoma evansi (T. evansi) calcium dependent phospholipase A2.
Yusuf Alkali +3 more
doaj +1 more source
Independent Recruitment of Different Types of Phospholipases A2 to the Venoms of Caenophidian Snakes: The Rise of PLA2-IIE within Pseudoboini (Dipsadidae). [PDF]
Mol Biol Evol, 2023 Bayona-Serrano JD +7 more
europepmc +1 more source
Action of pancreatic phospholipase A2 on phosphatidylcholine bilayers in different physical states [PDF]
, 1975 Jos A.F. Op den Kamp +2 more
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