Results 141 to 150 of about 9,957 (215)

Antimalarial activity of basic phospholipases A₂ isolated from Paraguayan Bothrops diporus venom against Plasmodium falciparum. [PDF]

Toxicon X, 2020
Vitorino KA, Alfonso JJ, Gómez AF, Santos APA, Antunes YR, Caldeira CADS, Gómez CV, Teles CBG, Soares AM, Calderon LA.   +9 more
europepmc   +1 more source

Evidence‐Based Clinical Practice Guidelines for Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) 2026

Hepatology Research, Volume 56, Issue 6, Page 887-902, June 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, with an increasing number of patients progressing to cirrhosis and hepatocellular carcinoma (HCC). Early identification of individuals at high risk for advanced fibrosis is essential for preventing liver‐related ...
Norio Akuta, Tomomi Kogiso, Kenichi Ikejima, Motoyuki Otsuka, Takumi Kawaguchi, Miwa Kawanaka, Hirokazu Takahashi, Nobuharu Tamaki, Hayato Nakagawa, Hayato Hikita, Hideki Fujii, Kanji Yamaguchi, Masato Yoneda, Kazuyoshi Kon, Akira Uchiyama, Yuya Seko, Sadatsugu Sakane, Ryuta Shigefuku, Naoto Fujiwara, Michihiro Iwaki, Takashi Kobayashi, Takuya Adachi, Yasuto Takeuchi, Tsubasa Tsutsumi, Dan Nakano, Kaoru Shibayama, Noriyo Urata, Hisamitsu Miyaaki, Hidekatsu Kuroda, Masahiro Koseki, Hirohito Sone, Yasuhiro Matsubayashi, Keisuke Kakisaka, Atsushi Takai, Kazuo Notsumata, Masataka Seike, Yoshiyuki Takei, Yoshifumi Takeyama, Susumu Eguchi, Sumio Watanabe, Hajime Isomoto, Hiroshi Yotsuyanagi, Takao Itoi, Tetsuo Takehara, Satoshi Mochida   +44 more
wiley   +1 more source

Distinct Roles of Myeloid‐ and Hepatocyte‐PLA2G6 Deletion in Mice With Metabolic Dysfunction‐Associated Steatotic Liver Disease

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Polymorphisms of group VIA calcium‐independent phospholipase A2 (iPLA2β or PLA2G6) are associated with Type‐2 diabetes, blood lipids and inflammation. Global deficiency in iPLA2β‐null mice elicited protection against hepatic steatosis but not hepatic inflammation after high‐fat diet (HFD) feeding.
Gang Li, Simone Staffer, Sabine Tuma‐Kellner, Uta Merle, Walee Chamulitrat   +4 more
wiley   +1 more source

High Relevance of Fatty Acid Oxidation in a Migrating Mammal, the Nathusius' Pipistrelle (Pipistrellus nathusii)

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Bats can sustain powered flight, but their reliance on fatty acid oxidation may limit long‐distance migration compared to birds. Using untargeted metabolomics, we analyzed blood metabolites of Nathusius' pipistrelle under controlled flight and migratory field conditions to identify fuel use.
Alesia Walker, Thuy Thanh Truong, Martin Klingenspor, Anders Hedenström, Gunars Pētersons, Philippe Schmitt‐Kopplin, Shannon E. Currie, Christian C. Voigt   +7 more
wiley   +1 more source

Oxytocin‐ und Vasopressin‐Photosonden zur Entschlüsselung der Neuropeptid‐Signalgebung mit hoher räumlicher und zeitlicher Präzision

Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.
Neue biokompatible Oxytocin‐ und Vasopressin‐Photosonden mit modernsten Photocages. Diese Photosonden sind inaktiv und können mit spezifischen Lichtwellen entschützt werden, was eine Rezeptoraktivierung mit hoher zeitlicher und räumlicher Kontrolle ermöglicht. Abbildung erstellt mit https://BioRender.com ZUSAMMENFASSUNG Das Oxytocin/Vasopressin (OT/VP)
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Corrigendum to "Small-molecule inhibitors as potential therapeutics and as tools to understand the role of phospholipases A2" [Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1864/6 2019 941-956]. [PDF]

Biochim Biophys Acta Mol Cell Biol Lipids, 2019
Nikolaou A, Kokotou MG, Vasilakaki S, Kokotos G.   +3 more
europepmc   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, Volume 65, Issue 22, 25 May 2026.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Alterations of the skeletal muscle contractile apparatus in necrosis induced by myotoxic snake venom phospholipases A₂: a mini-review. [PDF]

J Muscle Res Cell Motil
López-Dávila AJ, Lomonte B, Gutiérrez JM.   +2 more
europepmc   +1 more source

Temperature‐Dependent Leukocyte Agglutination and Type I Cryoglobulinemia Associated With IgM Monoclonal Gammopathy of Renal Significance (MGRS)

International Journal of Laboratory Hematology, Volume 48, Issue 3, Page 487-489, June 2026.
Yu Yang, Yating Li, Ziyi Zeng, Chenxue Qu, Meiling Wang   +4 more
wiley   +1 more source

On the role of protein disulfide isomerase in the retrograde cell transport of secreted phospholipases A2. [PDF]

PLoS One, 2015
Oberčkal J, Kovačič L, Šribar J, Leonardi A, Dolinar K, Pucer Janež A, Križaj I.   +6 more
europepmc   +1 more source