Secretory phospholipases A2 are secreted from ciliated cells and increase mucin and eicosanoid secretion from goblet cells. [PDF]
Tanabe T +3 more
europepmc +1 more source
The involvement of high mobility group 1 cytokine and phospholipases A2 in diabetic retinopathy. [PDF]
Gong Y +7 more
europepmc +1 more source
Conodipine-P1-3, the First Phospholipases A2 Characterized from Injected Cone Snail Venom. [PDF]
Möller C +4 more
europepmc +1 more source
Phospholipase PLA2G5-triggered hemolysis emerges as a contributor to sepsis lethality. [PDF]
Cavaillon JM.
europepmc +1 more source
Inhibition of the Myotoxicity Induced by Bothrops jararacussu Venom and Isolated Phospholipases A2 by Specific Camelid Single-Domain Antibody Fragments. [PDF]
Prado ND +16 more
europepmc +1 more source
Crystal structure and functional characterization of an Asp49 phospholipase A<sub>2</sub> from the bushmaster (Lachesis muta). [PDF]
Neyra Chama NE +9 more
europepmc +1 more source
Hepatic lipid quantity and quality in type 2 diabetes mellitus. [PDF]
Shimizu K +3 more
europepmc +1 more source
Cnidarian toxins: omics approaches and recombinant proteins. [PDF]
Vega-Tamayo JE +6 more
europepmc +1 more source
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Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including prostaglandins (PGs) and leukotrienes (LTs). The same reaction also produces lysophosholipids, which represent another class of lipid mediators.
I, Kudo, M, Murakami
openaire +3 more sources
Mammalian cells contain multiple structurally different phospholipase A2 enzymes that hydrolyse sn-2 fatty acid from membrane phospholipid. The low molecular weight secreted forms act extracellularly both as lipolytic enzymes and as agonists that bind to specific cell surface receptors.
, Gijón, , Leslie
openaire +2 more sources

