Results 131 to 140 of about 30,818 (310)

Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and high‐throughput RNA sequencing

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Nimodipine, an L‐type voltage‐gated calcium channel blocker, is an approved cerebral vasorelaxant. We hypothesized that nimodipine attenuates the pro‐inflammatory shift in microglial phenotypes. Here, we analysed the effects of nimodipine on morphological and functional microglial phenotypes as well as their transcriptomic ...
István Pesti   +10 more
wiley   +1 more source

In Silico Evaluation of Quercetin Methylated Derivatives on the Interaction with Secretory Phospholipases A2 from Crotalus durissus terrificus and Bothrops jararacussu. [PDF]

open access: yesPharmaceuticals (Basel), 2023
Belchor MN   +8 more
europepmc   +1 more source

Structure-property relationship of Co$_2$MnSi thin films in response to He$^+$ -irradiation [PDF]

open access: yesarXiv, 2018
We investigated the structure-property relationship of Co$_2$MnSi Heusler thin films upon the irradiation with He$^+$ ions. The variation of the crystal structure with increasing ion fluence has been probed using nuclear magnetic resonance (NMR) and transmission electron microscopy (TEM), and associated with the corresponding changes of the magnetic ...
arxiv  

Jabuticaba (Plinia jaboticaba) skin extracts as inhibitors of phospholipases A2 and proteases

open access: yesAnais da Academia Brasileira de Ciências
: The phenolic extracts of jabuticaba skin flour (JSF) were characterized by HPLC, and evaluated for their modulating action upon phospholipases A2 and proteases of snake venom, aiming at their possible use in the treatment of the various diseases ...
TAMARA R. MARQUES   +4 more
doaj   +1 more source

In Vitro Antiplasmodial Activity of Phospholipases A2 and a Phospholipase Homologue Isolated from the Venom of the Snake Bothrops asper

open access: yesToxins, 2012
The antimicrobial and antiparasite activity of phospholipase A2 (PLA2) from snakes and bees has been extensively explored. We studied the antiplasmodial effect of the whole venom of the snake Bothrops asper and of two fractions purified by ion-exchange ...
Juan Carlos Alarcón Pérez   +4 more
doaj   +1 more source

Phospholipases A2 as biomarkers in acute respiratory distress syndrome. [PDF]

open access: yesBiomed J, 2021
Kitsiouli E   +3 more
europepmc   +1 more source

Dynamic Role of Phospholipases A2 in Health and Diseases in the Central Nervous System. [PDF]

open access: yesCells, 2021
Sun GY   +6 more
europepmc   +1 more source

Transcriptional response in larvae of the generalist fruit fly Anastrepha obliqua feeding on three different tropical host plants

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We investigated the molecular basis of host switching by the phytophagous West Indian fruit fly (A. obliqua). Third‐instar larvae showed differential gene expression according to host plants: red mombin, mango, and carambola. The main gene categories differentially expressed were digestion, detoxification, and gene regulators.
Sandra M. Velasco‐Cuervo   +5 more
wiley   +1 more source

Bone marrow-derived cPLA2α contributes to renal fibrosis progression

open access: yesJournal of Lipid Research, 2018
The group IVA calcium-dependent cytosolic phospholipase A2 (cPLA2α) enzyme directs a complex “eicosanoid storm” that accompanies the tissue response to injury.
John R. Montford   +9 more
doaj  

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