Los envenenamientos causados por serpientes del género Bothrops constituyen un problema de salud en algunos países tropicales, no solamente por la mortalidad sino por el alto porcentaje de incapacidades físicas que ocasionan.
Tatiana LOBO E+6 more
doaj
Methylation of histidine-48 in pancreatic phospholipase A2. Role of histidine and calcium ion in the catalytic mechanism [PDF]
H.M. Verheij+6 more
openalex +1 more source
Intragenic PNPLA1 duplication in Labrador retrievers with nonepidermolytic ichthyosis
Background – Ichthyoses represent a heterogeneous group of cornification disorders characterised by epidermal scaling. Objectives – To describe the clinical, histopathological and genetic analysis of a Labrador retriever with nonepidermolytic ichthyosis, and the results of a Labrador retriever population screening for a newly detected PNPLA1 genomic ...
Stefan J. Rietmann+7 more
wiley +1 more source
Heart failure–induced activation of phospholipase iPLA2γ generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore [PDF]
Cedars, Ari M.+8 more
core +2 more sources
Hypoxic pregnancy promotes fibrosis and increases stress metabolites in the ovine fetal liver
Abstract Figure Legend: During hypoxic pregnancy, late gestation fetuses had increased periportal hepatic collagen deposition, an indicator of hepatic injury, with a unique profile of stress metabolites and adaptations in central carbon metabolism.
Molly M. McGuckin+8 more
wiley +1 more source
A Metalloproteinase Induces an Inflammatory Response in Preadipocytes with the Activation of COX Signalling Pathways and Participation of Endogenous Phospholipases A2. [PDF]
Janovits PM+3 more
europepmc +1 more source
Studies of the action of venom and venom constituents on Escherichia coli [PDF]
Studies of the action of venom and venom constituents on Escherichia coli. The antibacterial activity of honeybee venom (Apis mellifera) , three snake venoms (Naja naja sputatrix, Vipera russellii and Crotalus adamanteus) and the polypeptide melittin (a ...
Jane F. Stocker (7167641)
core
ABSTRACT Using LC–MS to screen and analyse the characteristics of components and biological systems is a new approach to study the pharmacological substance basis of traditional Chinese medicine, which has strong novelty in analytical science. This study analyses the antidepressant material basis of Zhizichi decoction through the integration strategy ...
Chuan Chai+7 more
wiley +1 more source
Development of aqueous two-phase systems-based approaches for the selective recovery of metalloproteases and phospholipases A2 toxins from Crotalus molossus nigrescens venom. [PDF]
Enriquez-Ochoa D+4 more
europepmc +1 more source
Analgesic flavonoids exhibit both antioxidant and anti‐inflammatory properties, with prenylated groups potentially enhancing their effects. In contrast, biflavonoids generally demonstrate either anti‐inflammatory or analgesic capabilities. Furthermore, key substitution sites in these compounds can be fully replaced by various organic functional groups,
Jingxian An+5 more
wiley +1 more source