Results 11 to 20 of about 271,068 (255)

The Involvement of Phospholipases A2 in Asthma and Chronic Obstructive Pulmonary Disease [PDF]

open access: yesMediators of Inflammation, 2013
The increased morbidity, mortality, and ineffective treatment associated with the pathogenesis of chronic inflammatory diseases such as asthma and chronic obstructive pulmonary disease (COPD) have generated much research interest.
Ewa Pniewska, Rafal Pawliczak
doaj   +3 more sources

Epitope-based antibody development against metalloproteinases and phospholipases A2 from Deinagkistrodon acutus venom [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases
Background: Deinagkistrodon acutus, or the hundred-pace snake, poses severe health risks due to its venom. Envenomation by this snake leads to complications such as hemorrhage, edema, and coagulopathy.
Haiting Zhu   +6 more
doaj   +2 more sources

Etomoxir-carnitine, a novel pharmaco-metabolite of etomoxir, inhibits phospholipases A2 and mitochondrial respiration [PDF]

open access: yesJournal of Lipid Research
Mitochondrial fatty acid oxidation serves as an essential process for cellular survival, differentiation, proliferation, and energy metabolism. Numerous studies have utilized etomoxir (ETO) for the irreversible inhibition of carnitine palmitoylcarnitine ...
Sung Ho Moon   +5 more
doaj   +2 more sources

Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review [PDF]

open access: yesIranian Journal of Medical Sciences, 2022
Venomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have toxic effects, and enzymatic peptide ...
Parisa Soltan-Alinejad   +3 more
doaj   +1 more source

Studies of potentially inflammatory phospholipases A2 and the effects of chloroquine-like agents

open access: yes, 1981
Studies of potentially inflammatory phospholipases A2 and the effects of chloroquine-like ...
Kalwant S. Authi (7166309)
core   +7 more sources

Viperidae snake venom phospholipase A2 . Biochemical targets for the action of protein in the human blood circulatory system. Part 1 (review of literature)

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
Snake venoms have been fervently studied for decades for two reasons: 1) high death rate due to snake bites; 2) numerous components of snake venoms prove useful in medicine and treatment of diverse pathologies. Snake venom phospholipases A2 are among the
L. V. Galebskaya   +3 more
doaj   +1 more source

PLA2G12B Mediates Arachidonic Acid Metabolism through Activation of the NF-κB Pathway to Promote Membrane Nephropathy

open access: yesKidney & Blood Pressure Research, 2023
Introduction: The disruption of podocyte structure and function are the main pathological mechanism of membranous nephropathy (MN). Phospholipases A2, Group XII B (PLA2G12B) was reported involved in the regulation of MN by interfering with arachidonic ...
Linlin Fu   +5 more
doaj   +1 more source

Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia [PDF]

open access: yesPeerJ, 2014
Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized.
Maritza Fernández Culma   +3 more
doaj   +2 more sources

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