Epitope-based antibody development against metalloproteinases and phospholipases A2 from Deinagkistrodon acutus venom [PDF]
Journal of Venomous Animals and Toxins including Tropical DiseasesBackground: Deinagkistrodon acutus, or the hundred-pace snake, poses severe health risks due to its venom. Envenomation by this snake leads to complications such as hemorrhage, edema, and coagulopathy.
Haiting Zhu +6 more
doaj +2 more sources
Etomoxir-carnitine, a novel pharmaco-metabolite of etomoxir, inhibits phospholipases A2 and mitochondrial respiration [PDF]
Journal of Lipid ResearchMitochondrial fatty acid oxidation serves as an essential process for cellular survival, differentiation, proliferation, and energy metabolism. Numerous studies have utilized etomoxir (ETO) for the irreversible inhibition of carnitine palmitoylcarnitine ...
Sung Ho Moon +5 more
doaj +2 more sources
Group XV Phospholipase A2, a Lysosomal Phospholipase A2 [PDF]
Progress in Lipid Research, 2011 A phospholipase A₂ was identified from MDCK cell homogenates with broad specificity toward glycerophospholipids including phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and phosphatidylglycerol. The phospholipase has the unique ability to transacylate short chain ceramides.
Yongqun He, Akira Abe, Robert Kelly
exaly +3 more sources
Secreted Phospholipases A2 of Snake Venoms: Effects on the Peripheral Neuromuscular System with Comments on the Role of Phospholipases A2 in Disorders of the CNS and Their Uses in Industry [PDF]
Toxins, 2013 Neuro- and myotoxicological signs and symptoms are significant clinical features of envenoming snakebites in many parts of the world. The toxins primarily responsible for the neuro and myotoxicity fall into one of two categories—those that bind to and ...
John B. Harris, Tracey Scott-Davey
doaj +2 more sources
Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review [PDF]
Iranian Journal of Medical Sciences, 2022 Venomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have toxic effects, and enzymatic peptide ...
Parisa Soltan-Alinejad +3 more
doaj +1 more source
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022 Snake venoms have been fervently studied for decades for two reasons: 1) high death rate due to snake bites; 2) numerous components of snake venoms prove useful in medicine and treatment of diverse pathologies. Snake venom phospholipases A2 are among the
L. V. Galebskaya +3 more
doaj +1 more source
Effective Soybean Oil Degumming by Immobilized Phospholipases A2 from Walterinnesia aegyptia Venom [PDF]
ACS OmegaAbir Ben Bacha, Mona Alonazi
doaj +2 more sources
Studies of potentially inflammatory phospholipases A2 and the effects of chloroquine-like agents
, 1981 Studies of potentially inflammatory phospholipases A2 and the effects of chloroquine-like ...
Kalwant S. Authi (7166309)
core +4 more sources
Kidney & Blood Pressure Research, 2023 Introduction: The disruption of podocyte structure and function are the main pathological mechanism of membranous nephropathy (MN). Phospholipases A2, Group XII B (PLA2G12B) was reported involved in the regulation of MN by interfering with arachidonic ...
Linlin Fu +5 more
doaj +1 more source
Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia [PDF]
PeerJ, 2014 Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized.
Maritza Fernández Culma +3 more
doaj +2 more sources