Results 21 to 30 of about 20,305 (246)

Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]

open access: yes, 2019
Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes.
Armando, Aaron   +2 more
core   +6 more sources

2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A2. [PDF]

open access: yes, 2017
Cytosolic phospholipase A2 (GIVA cPLA2) is the only PLA2 that exhibits a marked preference for hydrolysis of arachidonic acid containing phospholipid substrates releasing free arachidonic acid and lysophospholipids and giving rise to the generation of ...
Barbayianni, Efrosini   +10 more
core   +1 more source

Subcellular localization of the phospholipases A of rat heart: evidence for a cytosolic phospholipase A1.

open access: yesJournal of Lipid Research, 1985
During myocardial ischemia increased levels of lysoglycerophospholipids have been reported which may be deleterious to myocardial function. Phospholipases are presumed to be important in the regulation of this process.
G Nalbone, K Y Hostetler
doaj   +1 more source

Pancreatic phospholipase A2 activity in acute pancreatitis: A prognostic marker for early identification of patients at risk [PDF]

open access: yes, 2002
Remarkably elevated levels of phospholipase A(2) (PLA(2)) are measurable in human blood samples in cases of acute pancreatitis. The source of the enzyme was first thought to be exclusively the pancreas, but now it is generally accepted that two ...
Aufenanger, Johannes   +5 more
core   +1 more source

Signal-activated phospholipase regulation of leukocyte chemotaxis

open access: yesJournal of Lipid Research, 2009
Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated.
Martha K. Cathcart
doaj   +1 more source

Evaluation of the Brazilian functional fruit Morinda citrifolia as phospholipases A2 and proteases modulator

open access: yesPhytomedicine Plus, 2021
Morinda citrifolia is a plant widely consumed as food and used in folk medicine. However, there is little scientific information regarding its therapeutic properties. In this study, aqueous extracts from the peel and pulp of M.
Tamara Rezende Marques   +7 more
doaj   +1 more source

An amphitropic cAMP-binding protein in yeast mitochondria [PDF]

open access: yes, 1989
: We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W.   +43 more
core   +3 more sources

The relationship between lipoprotein-associated phospholipase A2 with cardiovascular risk factors in testosterone deficiency

open access: yesUrology Research and Practice, 2019
Objective: Lipoprotein-associated phospholipase A2 (Lp-PLA2) which is believed to play a role in atherosclerotic inflammatory process due to its function in hydrolysis of phospholipids and release of pro-inflammatory products, is considered as a novel ...
Mustafa Keleşoğlu   +6 more
doaj   +1 more source

Lysosomal phospholipase A2

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019
Lysosomal phospholipase A2 (PLA2G15) is a ubiquitous enzyme uniquely characterized by a subcellular localization to the lysosome and late endosome. PLA2G15 has an acidic pH optimum, is calcium independent, and acts as a transacylase in the presence of N-acetyl-sphingosine as an acceptor.
James A, Shayman, John J G, Tesmer
openaire   +2 more sources

Home - About - Disclaimer - Privacy