Results 21 to 30 of about 9,843 (241)

Secreted Phospholipases A2 of Snake Venoms: Effects on the Peripheral Neuromuscular System with Comments on the Role of Phospholipases A2 in Disorders of the CNS and Their Uses in Industry [PDF]

Toxins, 2013
Neuro- and myotoxicological signs and symptoms are significant clinical features of envenoming snakebites in many parts of the world. The toxins primarily responsible for the neuro and myotoxicity fall into one of two categories—those that bind to and ...
John B. Harris, Tracey Scott-Davey
doaj   +2 more sources

Search for and functional annotation of multi-domain PLA2 family proteins in flatworms

Вавиловский журнал генетики и селекции
The phospholipase A2 (PLA2) is a superfamily of hydrolases that catalyze the hydrolysis of phospholipids and play a key role in many molecular processes in the cells and the organism as a whole.
M. E. Bocharnikova, I. I. Turnaev, D. A. Afonnikov   +2 more
doaj   +2 more sources

Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review [PDF]

Iranian Journal of Medical Sciences, 2022
Venomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have toxic effects, and enzymatic peptide ...
Parisa Soltan-Alinejad, Hamzeh Alipour, Davood Meharabani, Kourosh Azizi   +3 more
doaj   +1 more source

Effective Soybean Oil Degumming by Immobilized Phospholipases A2 from Walterinnesia aegyptia Venom [PDF]

ACS Omega
Abir Ben Bacha, Mona Alonazi
doaj   +2 more sources

Viperidae snake venom phospholipase A2 . Biochemical targets for the action of protein in the human blood circulatory system. Part 1 (review of literature)

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
Snake venoms have been fervently studied for decades for two reasons: 1) high death rate due to snake bites; 2) numerous components of snake venoms prove useful in medicine and treatment of diverse pathologies. Snake venom phospholipases A2 are among the
L. V. Galebskaya, L. V. Vasina, M. A. Galkin, Yu. V. Tarasova   +3 more
doaj   +1 more source

PLA2G12B Mediates Arachidonic Acid Metabolism through Activation of the NF-κB Pathway to Promote Membrane Nephropathy

Kidney & Blood Pressure Research, 2023
Introduction: The disruption of podocyte structure and function are the main pathological mechanism of membranous nephropathy (MN). Phospholipases A2, Group XII B (PLA2G12B) was reported involved in the regulation of MN by interfering with arachidonic ...
Linlin Fu, Jinliang Ping, Fei Guo, Jiafeng Song, Mingjun Luo, Lijing Chen   +5 more
doaj   +1 more source

Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia [PDF]

PeerJ, 2014
Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized.
Maritza Fernández Culma, Jaime Andrés Pereañez, Vitelbina Núñez Rangel, Bruno Lomonte   +3 more
doaj   +2 more sources

Inflammation and Oxidative Stress in Snakebite Envenomation: A Brief Descriptive Review and Clinical Implications

Toxins, 2022
Snakebite envenoming is a pathological condition which may occur in response to the injection of venom. Snake venoms contain a complex mixture of biologically active molecules which are responsible for a broad spectrum of clinical manifestations, ranging
Dabor Resiere, Hossein Mehdaoui, Remi Neviere   +2 more
doaj   +1 more source

Novel Bradykinin-Potentiating Peptides and Three-Finger Toxins from Viper Venom: Combined NGS Venom Gland Transcriptomics and Quantitative Venom Proteomics of the Azemiops feae Viper

Biomedicines, 2020
Feae’s viper Azemipos feae belongs to the Azemiopinae subfamily of the Viperidae family. The effects of Viperidae venoms are mostly coagulopathic with limited neurotoxicity manifested by phospholipases A2. From A.
Vladislav V. Babenko, Rustam H. Ziganshin, Christoph Weise, Igor Dyachenko, Elvira Shaykhutdinova, Arkady N. Murashev, Maxim Zhmak, Vladislav Starkov, Anh Ngoc Hoang, Victor Tsetlin, Yuri Utkin   +10 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source