Results 51 to 60 of about 9,843 (241)

Mannose‐Glycated Metal‐Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Immunomodulatory metal‐phenolic microcapsules (mMPMs) is developed in this study that leverages dopamine‐modified hyaluronic acid and FeIII assemble on mannose‐glycated bovine serum albumin microbubbles. mMPMs effectively promote macrophage internalization and M1 polarization, enhancing pro‐inflammatory responses.
Xin Tan   +9 more
wiley   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

P/2010 A2 LINEAR II: dynamical dust modelling [PDF]

open access: yes, 2012
P/2010 A2 is an object on an asteroidal orbit that was observed to have an extended tail or debris trail in January 2010. In this work, we fit the outburst of P/2010 A2 with a conical burst model, and verify previous suspicions that this was a one--time collisional event rather than an sustained cometary outburst, implying that P/2010 A2 is not a new ...
arxiv   +1 more source

Profiling Serine Hydrolases in the Leishmania Host‐Pathogen Interactome Using Cell‐Permeable Activity‐Based Fluorophosphonate Probes

open access: yesChemBioChem, Accepted Article.
Leishmaniasis, a vector borne neglected tropical disease, caused by the protozoan parasite Leishmania, is a major global public health challenge with millions of new cases annually. Treatment of leishmaniasis is difficult for many reasons including a multiple life‐cycle stages, involving both an infective insect vector form, the promastigote, and a ...
Jaime A. Isern   +7 more
wiley   +1 more source

Observation of [CI] toward the GL 2591 and W28 A2 Molecular Outflows [PDF]

open access: yes, 1994
Molecular outflows associated with GL 2591 and W28 A2 were observed in the 492 GHz [CI] line. Upper limits are set on the [CI] emission in the extremely high velocity line wings. These limits are discussed in terms of wind-driven and jet-driven models of molecular outflows.
arxiv   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok   +5 more
wiley   +1 more source

Chemo‐Enzymatic Synthesis of Mixed Docosahexaenoic Acid Phosphatidylcholine Conjugates

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
An efficient chemo‐enzymatic synthesis method is proposed for the production of mixed DHA (Docosahexaenoic acid) phosphatidylcholines, allowing access to both regioisomers with DHA positioned at either the sn1 or sn2 site. Regioisomers of acetate derivatives (AceDoPC®, DoAcePC, stabilized forms of LPC‐DHA) and phenolic‐DHA‐PCs (antioxidant drugs) were ...
Jordan Lehoux   +6 more
wiley   +1 more source

Signal-activated phospholipase regulation of leukocyte chemotaxis

open access: yesJournal of Lipid Research, 2009
Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated.
Martha K. Cathcart
doaj  

Evaluation of the Brazilian functional fruit Morinda citrifolia as phospholipases A2 and proteases modulator

open access: yesPhytomedicine Plus, 2021
Morinda citrifolia is a plant widely consumed as food and used in folk medicine. However, there is little scientific information regarding its therapeutic properties. In this study, aqueous extracts from the peel and pulp of M.
Tamara Rezende Marques   +7 more
doaj  

Highly Complex Magnetic Structures Resulting From Hierarchical Phase Separation in AlCo(Cr)FeNi High Entropy Alloys [PDF]

open access: yesarXiv, 2021
Magnetic high entropy alloys (HEAs) are a new category of high-performance magnetic materials, with multi-component concentrated compositions and complex multi-phase structures. Although there have been numerous reports of their interesting magnetic properties, there is very limited understanding about the interplay between their hierarchical multi ...
arxiv  

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