Results 91 to 100 of about 18,478 (212)
, 2017 Proteins from the spinal ligament cells of wild-type and null mice were separated using two-dimensional gel electrophoresis and stained with Pro-Q Diamond phosphoprotein gel stain (Thermo Fisher Scientific, Waltham, MA, USA) followed by SYPRO Ruby protein gel stain (Thermo Fisher Scientific).
openaire +1 more source
Phosphoproteomic Analysis Reveals the Importance of Kinase Regulation During Orbivirus Infection. [PDF]
, 2017 Bluetongue virus (BTV) causes infections in wild and domesticated ruminants with high morbidity and mortality and is responsible for significant economic losses in both developing and developed countries.
Emmott, Edward +2 more
core +1 more source
Regulation of yeast central metabolism by enzyme phosphorylation
Molecular Systems Biology, 2012 As a frequent post‐translational modification, protein phosphorylation regulates many cellular processes. Although several hundred phosphorylation sites have been mapped to metabolic enzymes in Saccharomyces cerevisiae, functionality was demonstrated for
Ana Paula Oliveira +5 more
doaj +1 more source
Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development [PDF]
, 2017 Asymmetric cell divisions are required for cellular diversity and defects can lead to altered daughter cell fates and numbers. In a genetic screen for C.
A Leung +55 more
core +2 more sources
MedComm, Volume 7, Issue 2, February 2026.The role of FOSL1 in TMZ response to GBM. FOSL1 enhances TMZ resistance by promoting cell cycle progression, MGMT expression, and IL‐6‐pSTAT3Tyr705‐stemness axis. VEM is a potential candidate drug for alleviating TMZ resistance in GBM, highlighting a new approach for chemo‐resistant GBM treatment.
JeongMin Sim +16 more
wiley +1 more source
Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells. [PDF]
, 2018 Deregulated signal transduction and energy metabolism are hallmarks of cancer and both play a fundamental role in tumorigenesis. While it is increasingly recognised that signalling and metabolism are highly interconnected, the underpinning mechanisms of ...
Costa, Ana SH +7 more
core +2 more sources
Aging Cell, Volume 25, Issue 2, February 2026.Partial chemical reprogramming significantly increases mitochondrial interaction networks, affects mitochondrial morphology, speeds up mitochondrial movement dynamics, increases mitochondrial transmembrane potential, and induces TCA cycle stress. These changes in mitochondrial function contribute to lipid droplet accumulation, acute kidney injury, and ...
Wayne Mitchell +9 more
wiley +1 more source
The driver landscape of sporadic chordoma. [PDF]
, 2017 Chordoma is a malignant, often incurable bone tumour showing notochordal differentiation. Here, we defined the somatic driver landscape of 104 cases of sporadic chordoma. We reveal somatic duplications of the notochordal transcription factor brachyury (T)
Alexandrov, Ludmil B +31 more
core +2 more sources
Phosphoproteomic differences in major depressive disorder postmortem brains indicate effects on synaptic function [PDF]
, 2012 There is still a lack in the molecular comprehension of major depressive disorder (MDD) although this condition affects approximately 10% of the world population.
BK Krueger +62 more
core +2 more sources
Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages [PDF]
, 2016 Macrophages exhibit a phenotypic plasticity that enables them to orchestrate specific immune responses to distinct threats. The microbial product lipopolysaccharide (LPS) and the extracellular matrix glycoprotein tenascin-C are released during bacterial ...
Lim, JMP +3 more
core +3 more sources