Results 101 to 110 of about 18,478 (212)
Exercise-responsive phosphoproteins in the heart. [PDF]
Endurance exercise improves cardiac performance and affords protection against cardiovascular diseases but the signalling events that mediate these benefits are largely unexplored.
Burniston, JG +3 more
core +1 more source
Phosphoproteomics-Based Systems Analysis of Signal Transduction Networks [PDF]
, 2012 Signal transduction systems coordinate complex cellular information to regulate biological events such as cell proliferation and differentiation. Although the accumulating evidence on widespread association of signaling molecules has revealed essential ...
Hiroko Kozuka-Hata +2 more
core +2 more sources
Age-Related Differences in Plasma Proteins: How Plasma Proteins Change from Neonates to Adults
, 2015 The incidence of major diseases such as cardiovascular disease, thrombosis and cancer increases with age and is the major cause of mortality world-wide, with neonates and children somehow protected from such diseases of ageing. We hypothesized that there
Ignjatovic, Vera +6 more
core +1 more source
Phosphoproteome Discovery in Human Biological Fluids
Proteomes, 2016 Phosphorylation plays a critical role in regulating protein function and thus influences a vast spectrum of cellular processes. With the advent of modern bioanalytical technologies, examination of protein phosphorylation on a global scale has become one ...
Francesco Giorgianni +1 more
doaj +1 more source
LymPHOS 2.0: An update of a phosphosite database of primary human T cells [PDF]
, 2017 LymPHOS is a web-oriented database containing peptide and protein sequences and spectrometric information on the phosphoproteome of primary human T-Lymphocytes.
Abián, Joaquín +4 more
core +1 more source
Kinase activities in pancreatic ductal adenocarcinoma with prognostic and therapeutic avenues
Molecular OncologyPancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a limited number of known driver mutations but considerable cancer cell heterogeneity.
Andrea Vallés‐Martí +11 more
doaj +1 more source
Cellular reprogramming through mitogen-activated protein kinases
Frontiers in Plant Science, 2015 Mitogen-activated protein kinase (MAPK) cascades are conserved eukaryote signaling modules where MAPKs, as the final kinases in the cascade, phosphorylate protein substrates to regulate cellular processes.
Justin eLee +7 more
doaj +1 more source
Plasmodium falciparum infection induces dynamic changes in the erythrocyte phospho-proteome [PDF]
, 2016 The phosphorylation status of red blood cell proteins is strongly altered during the infection by the malaria parasite Plasmodium falciparum. We identify the key phosphorylation events that occur in the erythrocyte membrane and cytoskeleton during ...
Bouyer, Guillaume +7 more
core +4 more sources
Elucidating Host-Pathogen Interactions Based on Post-Translational Modifications Using Proteomics Approaches [PDF]
, 2015 Microbes with the capability to survive in the host tissue and efficiently subvert its innate immune responses can cause various health hazards. There is an inherent need to understand microbial infection patterns and mechanisms in order to develop ...
Jers, Carsten +2 more
core +1 more source
Molecular OncologyB‐cell chronic lymphocytic leukemia (B‐CLL) is characterized by highly heterogeneous genomic alterations and altered signaling pathways, with limited studies on its proteome. Our study presents a comprehensive analysis of the proteome and phosphoproteome
Paula Díez +17 more
doaj +1 more source