Results 21 to 30 of about 12,613 (178)
Loss of gq/11 genes does not abolish melanopsin phototransduction.
PLoS ONE, 2014 In mammals, a subset of retinal ganglion cells (RGCs) expresses the photopigment melanopsin, which renders them intrinsically photosensitive (ipRGCs). These ipRGCs mediate various non-image-forming visual functions such as circadian photoentrainment and ...
Kylie S Chew +4 more
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A Single Residue Mutation in the Gαq Subunit of the G Protein Complex Causes Blindness in Drosophila
G3: Genes, Genomes, Genetics, 2018 Heterotrimeric G proteins play central roles in many signaling pathways, including the phototransduction cascade in animals. However, the degree of involvement of the G protein subunit Gαq is not clear since animals with previously reported strong loss ...
Jinguo Cao +10 more
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BMC Biology, 2012 Background Calcium-activated photoproteins are luciferase variants found in photocyte cells of bioluminescent jellyfish (Phylum Cnidaria) and comb jellies (Phylum Ctenophora).
Schnitzler Christine E +14 more
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Frontiers in Medicine, 2022 Intrinsic optical signal (IOS) imaging of the retina, also termed as optoretinogram or optoretinography (ORG), promises a non-invasive method for the objective assessment of retinal function.
Tae-Hoon Kim +4 more
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InsectsOpsin plays a regulatory role in phototaxis of Diaphorina citri, functioning as the initial station in the phototransduction cascade. Our study aimed to explore the D. citri phototransduction pathway to identify elicitors that may enhance D.
Shao-Ping Chen +4 more
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Deep Diversity: Extensive Variation in the Components of Complex Visual Systems across Animals
Cells, 2022 Understanding the molecular underpinnings of the evolution of complex (multi-part) systems is a fundamental topic in biology. One unanswered question is to what the extent do similar or different genes and regulatory interactions underlie similar complex
Oliver Vöcking +3 more
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eLifeComputation in neural circuits relies on the judicious use of nonlinear circuit components. In many cases, multiple nonlinear components work collectively to control circuit outputs. Separating the contributions of these different components is difficult,
Qiang Chen +5 more
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Implications of dimeric activation of PDE6 for rod phototransduction [PDF]
Open Biology, 2018 We examine the implications of a recent report providing evidence that two transducins must bind to the rod phosphodiesterase to elicit significant hydrolytic activity.
Trevor D. Lamb +2 more
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Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
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Bicarbonate and Ca2+ sensing modulators activate photoreceptor ROS-GC1 synergistically
Frontiers in Molecular Neuroscience, 2016 Photoreceptor ROS-GC1, a prototype subfamily member of the membrane guanylate cyclase family, is a central component of phototransduction. It is a single transmembrane-spanning protein, composed of modular blocks.
Teresa eDuda +3 more
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