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Animal Cells and Systems, 2023 Visual impairment is occasionally observed in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). Although uveitis and optic neuritis have been reported in MS and EAE, the precise mechanisms underlying the ...
Sungmoo Hong +4 more
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Phototransduction and the Evolution of Photoreceptors [PDF]
Current Biology, 2010 Photoreceptors in metazoans can be grouped into two classes, with their photoreceptive membrane derived either from cilia or microvilli. Both classes use some form of the visual pigment protein opsin, which together with 11-cis retinaldehyde absorbs light and activates a G-protein cascade, resulting in the opening or closing of ion channels ...
Fain, Gordon L. +2 more
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Frontiers in Neuroanatomy, 2022 Cubomedusae, or box jellyfish, have a complex visual system comprising 24 eyes of four types. Like other cnidarians, their photoreceptor cells are ciliary in morphology, and a range of different techniques together show that at least two of the eye types—
Anders Garm +3 more
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Current issues in invertebrate phototransduction: Second messengers and ion conductances [PDF]
, 1997 Investigation of phototransduction in invertebrate photoreceptors has revealed many physiological and biochemical features of fundamental biological importance. Nonetheless, no complete picture of phototransduction has yet emerged.
Bacigalupo Vicuña, Juan +3 more
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Drosophila Photo-transduction Simulator
Journal of Open Research Software, 2013 This software contains detailed modelling of the single photon response, the quantum bump, of fly photoreceptors. All known components participating in the primary phototransduction process are taken into account, and estimates are given for both the ...
Konstantin Nikolic, Joaquim Loizu
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Phototransduction and light-iinducted mitochondrial activation in blowfly compound eyes [PDF]
, 1992 The present thesis considered two aspects of phototransduction in the blowfly Calliphora vicina mutant chalky. First, we studied the mechanism of the basis process, conversion of light to an electrical signal.
Mojet, Martinus Hendrik
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A Single Residue Mutation in the Gαq Subunit of the G Protein Complex Causes Blindness in Drosophila
G3: Genes, Genomes, Genetics, 2018 Heterotrimeric G proteins play central roles in many signaling pathways, including the phototransduction cascade in animals. However, the degree of involvement of the G protein subunit Gαq is not clear since animals with previously reported strong loss ...
Jinguo Cao +10 more
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Melanopsin phototransduction: beyond canonical cascades
, 2021 Melanopsin is a visual pigment that is expressed in a small subset of intrinsically photosensitive retinal ganglion cells (ipRGCs). It is involved in regulating non-image forming visual behaviors, such as circadian photoentrainment and the pupillary ...
Robinson, Phyllis +3 more
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Frontiers in Medicine, 2022 Intrinsic optical signal (IOS) imaging of the retina, also termed as optoretinogram or optoretinography (ORG), promises a non-invasive method for the objective assessment of retinal function.
Tae-Hoon Kim +4 more
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BMC Biology, 2012 Background Calcium-activated photoproteins are luciferase variants found in photocyte cells of bioluminescent jellyfish (Phylum Cnidaria) and comb jellies (Phylum Ctenophora).
Schnitzler Christine E +14 more
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