Results 31 to 40 of about 2,726 (151)
Novel role for non-invasive neuromodulation techniques in central respiratory dysfunction
Frontiers in Neuroscience, 2023 Respiration is a crucial steady-state function of human life. Central nervous system injury can damage the central respiratory pattern generator (CRPG) or interrupt its outflow, leading to central respiratory paralysis and dysfunction, which can endanger
Lan Lv +5 more
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Deregulation of ZPR1 causes respiratory failure in spinal muscular atrophy
Scientific Reports, 2017 Spinal muscular atrophy (SMA) is caused by the low levels of survival motor neuron (SMN) protein and is characterized by motor neuron degeneration and muscle atrophy.
Naresh K. Genabai +5 more
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Atypical protein kinase C expression in phrenic motor neurons of the rat [PDF]
Neuroscience, 2010 Atypical protein kinase C (PKC) isoforms play important roles in many neural processes, including synaptic plasticity and neurodegenerative diseases. Although atypical PKCs are expressed throughout the brain, there are no reports concerning their expression in central neural regions associated with respiratory motor control.
C H, Guenther +4 more
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Lightning strike: a first case of unilateral diaphragmatic paralysis
Clinics and Practice, 2011 Lightning injury is the second most common cause of weather-related deaths in the United States. Despite the several neurological complications such as polyneuropathy, myelopathy, spinal cord injury, motor neuron disease due to the lightning-induced ...
Timucin Alar +2 more
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Spinal Metaplasticity in Respiratory Motor Control
Frontiers in Neural Circuits, 2015 A hallmark feature of the neural system controlling breathing is its ability to exhibit plasticity. Less appreciated is the ability to exhibit metaplasticity, a change in the capacity to express plasticity (ie. plastic plasticity). Recent advances in our
Gordon S Mitchell, Daryl P Fields
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ERJ Open Research, 2017 The aim of this study was to evaluate the feasibility of unilateral diaphragmatic reinnervation in humans by the inferior laryngeal nerve. This pilot study included chronically ventilated tetraplegic patients with destruction of phrenic nerve motoneurons.
Eric Verin +8 more
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Why individuals with cerebral palsy are at higher risk for respiratory complications from COVID-19
Journal of Pediatric Rehabilitation Medicine, 2020 Respiratory dysfunction is a leading cause of morbidity and mortality in individuals with cerebral palsy (CP). In children and adults with CP, movement and physical function is always affected.
Joline E. Brandenburg +2 more
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Neurobiology of Disease, 2021 Chondroitin sulfate proteoglycans (CSPGs), up-regulated in and around the lesion after traumatic spinal cord injury (SCI), are key extracellular matrix inhibitory molecules that limit axon growth and consequent recovery of function.
Lan Cheng +9 more
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Respiratory axon regeneration in the chronically injured spinal cord
Neurobiology of Disease, 2021 Promoting the combination of robust regeneration of damaged axons and synaptic reconnection of these growing axon populations with appropriate neuronal targets represents a major therapeutic goal following spinal cord injury (SCI).
Lan Cheng +7 more
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Functional and Morphological Assessment of Diaphragm Innervation by Phrenic Motor Neurons
Journal of Visualized Experiments, 2015 This protocol specifically focuses on tools for assessing phrenic motor neuron (PhMN) innervation of the diaphragm at both the electrophysiological and morphological levels. Compound muscle action potential (CMAP) recording following phrenic nerve stimulation can be used to quantitatively assess functional diaphragm innervation by PhMNs of the cervical
Melanie, Martin +3 more
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