Results 101 to 110 of about 23,818,397 (163)
Small, Volume 22, Issue 55, 1 October 2026.Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini +3 more
wiley +1 more source
Bioequivalence risk assessment of oral formulations containing racemic ibuprofen through a chiral physiologically based pharmacokinetic model of ibuprofen enantiomers [PDF]
[EN] The characterization of the time course of ibuprofen enantiomers can be useful in the selection of the most sensitive analyte in bioequivalence studies.
M. Cuquerella-Gilabert +5 more
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Journal of Diabetes Investigation, Volume 17, Issue 10, Page 1807-1815, October 2026.ABSTRACT Background The purpose of the study was to evaluate the accuracy, safety, and usability of a real‐time Continuous Glucose Monitoring (CGM) system compared with venous blood glucose (vBG) in children and adolescents. Methods The study enrolled 81 participants aged from 3 to 17 at three sites in China. Two sensors (GS1, SiBionics, Shenzhen) were
Bingyan Cao +7 more
wiley +1 more source
Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.ABSTRACT Background The steady evolution of aesthetic and regenerative medicine has driven a paradigm shift from purely corrective interventions toward biologically oriented therapies focused on tissue remodeling, extracellular matrix modulation, and regenerative optimization.
Antony de Paula Barbosa
wiley +1 more source
Development of Physiologically Based Pharmacokinetic (PBPK) Modeling
In this Special Issue, “Development of Physiologically Based Pharmacokinetic (PBPK) Modeling”, readers can find a selection of articles that discuss the most current challenges and advances in this area [...
S\ue1nchez-Dengra, B\ue1rbara +3 more
core +1 more source
Physiologically-Based Pharmacokinetic Modeling of Acetaminophen Metabolism and Toxicity [PDF]
, 2012 Acetaminophen is a common analgesic and antipyretic. Metabolism of acetaminophen and acetaminophen-induced liver necrosis are predicted using physiologically-based pharmacokinetic (PBPK) modeling. Pharmacokinetic means the model determines where the drug
Ng, David M., Navid, Ali
core
PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang +13 more
wiley +1 more source
Next‐Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca
ChemBioChem, Volume 27, Issue 17, 14 September 2026.Biocatalysis is strengthening AstraZeneca's manufacture of active pharmaceutical ingredients through faster development, robust scale‐up, and lower environmental impact. Case studies illustrate where biocatalysis delivers greatest value, while enabling platforms, teams, and partnerships shape its next phase.
Alba Diaz‐Rodriguez +4 more
wiley +1 more source
Physiologically-based pharmacokinetic modeling for predicting caffeine/theophylline-ciprofloxacin interactions [PDF]
, 2013 Dynamics of interactions between the drugs caffeine, theophylline, and ciprofloxacin are predicted using physiologically-based pharmacokinetic (PBPK) modeling.
Ng, David M., Navid, Ali
core
, 2016 Jee Sun Min,1 Doyun Kim,1 Jung Bae Park,1 Hyunjin Heo,1 Soo Hyeon Bae,2 Jae Hong Seo,1 Euichaul Oh,1 Soo Kyung Bae1 1Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, 2Department of
Kim D +7 more
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