Results 111 to 120 of about 23,818,397 (163)

Frequently Asked Questions Related to the Commission on Evidence-Based Policymaking's Report

, 2017
List of frequently-asked questions regarding the final report of the U.S. Commission on Evidence-Based Policymaking with answers and clarifications. Questions are broken into five topics: general, National Secure Data Service (NSDS), privacy, access ...
United States. Commission on Evidence-Based Policymaking.
core  

A physiologically based biopharmaceutics modeling (PBBM) framework for characterizing formulation-dependent food effects: Paving the road towards fed state virtual BE studies for itraconazole amorphous solid dispersions

This study leverages physiologically based biopharmaceutics modeling (PBBM) to predict the clinical performance of two itraconazole (ITRA) amorphous solid dispersions (ASDs), Sempera® and Tolsura®, under fasted and fed state conditions, exploring the ...
Charbe, Nitin Bharat, Shoyaib, Abdullah Al, Pal, Arindom, Polli, James E., Zhao, Liang, Cristofoletti, Rodrigo, Rudolph, Niklas, Plano, David, Boyce, Heather J., Wu, Fang, Dressman, Jennifer Joy   +10 more
core   +1 more source

Physiologically-Based Pharmacokinetic Modeling for Predicting Drug-Drug Interactions [PDF]

, 2011
Dynamics of interactions between the drugs caffeine and ciprofloxacin are predicted using physiologically-based pharmacokinetic (PBPK) modeling.
Ng, David M., Navid, Ali
core  

Acalabrutinib Maleate Tablets: The Physiologically Based Biopharmaceutics Model behind the Drug Product Dissolution Specification

Acalabrutinib maleate tablets correspond to an improved formulation compared to acalabrutinib capsules as they can be dosed with and without acid reducing agents and therefore benefit more cancer patients.
James Mann (4385431), Vivien McAlpine (14704241), Xavier Pepin (14704238), Andrea Moir (14704244)   +3 more
core   +1 more source

GastroPlus® as simulating/ conducting software for modeling physiologically-based pharmacokinetics & physiologically based biopharmaceutics.

Ma’aen Journal for Medical Sciences
Yasir Qasim Almajidi, Rafif Raad Faisal, Ahmed Yaseen, Maher abdulrazzaq luqman al-hakeem   +3 more
doaj   +1 more source

Impact of Food Physical Properties on Oral Drug Absorption: A Comprehensive Review

Drug Design, Development and Therapy
Ziyang Wang,1 Wen Xu,2 Dan Liu,3 Xiuqi Li,1 Shupeng Liu,1 Xiaofei Wu,1 Hongyun Wang1 1Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s ...
Wang Z, Xu W, Liu D, Li X, Liu S, Wu X, Wang H   +6 more
doaj  

Emerging perspectives on leveraging physiologically based biopharmaceutics modeling (PBBM) for BCS class III biowaivers: A webinar summary. [PDF]

J Pharm Sci
Fang L, Veerasingham S, Xu Y, Garcia-Arieta A, Kollipara S, Kanagasabapathy Y, Ahmed T, Martins FS, Suarez-Sharp S.   +8 more
europepmc   +1 more source

Physiologically Based Biopharmaceutics Modeling (PBBM)

, 2021
Lawrence J. Lesko, Alejandra Schiavo, Manuel Ibarra   +2 more
core   +1 more source

Apllied Biopharmaceutics

, 2005
xx, 892 hal.; ill ...
Pong, Susana WU, Shargel, Leon
core  

Mechanism-Based Pharmacokinetic and Pharmacodynamic Modeling. [PDF]

Pharmaceutics
Świerczek A.
europepmc   +1 more source