Results 11 to 20 of about 5,394 (197)

Anti-adherence capacity of phytosphingosine on titanium surfaces. [PDF]

J Biomater Appl
Firm soft tissue attachment on oral implant components together with good bacterial control are important prerequisites for uneventful implant healing. TiO 2 coatings have been shown to enhance human gingival fibroblast attachment, but the coating does not have antimicrobial properties.
Liinoja E, Areid N, Närvä E, Bikker FJ, Loimaranta V, Närhi TO.   +5 more
europepmc   +3 more sources

Impact of Ceramide Acyl Chain Length on Human Skin Barrier Recovery and Hydration. [PDF]

J Cosmet Dermatol
ABSTRACT Objective To compare the effects of ceramide acyl chain length on human skin barrier function. Methods Mixtures of phytoceramide containing non‐hydroxy fatty acids (CER NPs) with different acyl chain lengths and corresponding test creams were prepared: C16–C24 CER NP and C24–C30 CER NP (ultra‐long‐chain, ULC CER NP).
Gwon DH, Choi HK, Lee EO, Hong SK, Park CS, Kim JW, Liu KH.   +6 more
europepmc   +2 more sources

Synthesis of 1-Substituted-phytosphingosine : Novel Protection of Phytosphingosine [PDF]

Bulletin of the Korean Chemical Society, 2003
Medicinal Science Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yusong, Daejeon 305-600, KoreaReceived December 13, 2002Key Words : Phytosphingosine, 1-Substituted-phytosphingosine, Phytosphingosine 1-phosphate, Sphin-gosine, Cyclic carbonatePhytosphingosine, one of the major sphingosine deriva-tives was found in ...
Su Yeon Jo, Hyoung Cheul Kim, Seung Woo Woo, Min Jung Seo, Gehyeong Lee, Hyoung Rae Kim   +5 more
openaire   +2 more sources

Statistical Study of Low-Intensity Single-Molecule Recognition Events Using DeepTip^TM Probes: Application to the Pru p 3-Phytosphingosine System

Biomimetics, 2023
The interaction between the plant lipid transfer protein Pru p 3 and phytosphingosine was assessed using an atomic force microscope. Phytosphingosine was covalently immobilized on DeepTipTM probes and Pru p 3 on MicroDeckTM functionalized substrates ...
Rafael Daza, María Garrido-Arandia, Daniel Corregidor-Ortiz, Carla Isabel Pérez, Luis Colchero, Raquel Tabraue-Rubio, Manuel Elices, Gustavo V. Guinea, Araceli Diaz-Perales, José Pérez-Rigueiro   +9 more
doaj   +1 more source

Double-Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration. [PDF]

Aging Cell
A novel drug combination (NMN + API) promotes musculoskeletal regeneration in aging. By boosting NAD+, it activates SIRT3 to suppress cellular senescence and enhance differentiation into chondrocytes, osteoblasts, and myocytes. Oral administration reshapes the gut microbiota, increasing production of the anti‐aging metabolite PHS.
Yu J, Hou M, Deng Y, Yu C, Liu Y, Kang K, Xia X, Li X, Yang H, Jiang D, Xu W, Zhang Y, Zhu X.   +12 more
europepmc   +2 more sources

The molecular mechanism of phytosphingosine binding to FFAR4/GPR120 differs from that of other fatty acids

FEBS Open Bio, 2021
Free fatty acid receptor 4 (FFAR4)/GPR120 comprises a receptor for medium‐ and long‐chain fatty acids. We previously identified phytosphingosine (PHS) as a novel ligand of FFAR4.
Tomotaka Nagasawa, Masaki Horitani, Shin‐ichi Kawaguchi, Shigeki Higashiyama, Yoichiro Hama, Susumu Mitsutake   +5 more
doaj   +1 more source

The major plant sphingolipid long chain base phytosphingosine inhibits growth of bacterial and fungal plant pathogens

Scientific Reports, 2022
Sphingolipid long chain bases (LCBs) are building blocks of sphingolipids and can serve as signalling molecules, but also have antimicrobial activity and were effective in reducing growth of a range of human pathogens.
René Glenz, Agnes Kaiping, Delia Göpfert, Hannah Weber, Benjamin Lambour, Marvin Sylvester, Christian Fröschel, Martin J. Mueller, Mohamed Osman, Frank Waller   +9 more
doaj   +1 more source

Cis-unsaturated sphingolipids support growth of sphingoid base-deficient yeast but impair plasma membrane integrity. [PDF]

FEBS Open Bio
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Higuchi T, Sugihara S, Ishibashi Y, Yushi K, Yamauchi H, Tani M.   +5 more
europepmc   +2 more sources

Phytosphingosine induced mitochondria‐involved apoptosis [PDF]

Cancer Science, 2005
Sphingolipids are putative intracellular signal mediators in cell differentiation, growth inhibition, and apoptosis. Sphingosine, sphinganine, and phytosphingosine are structural analogs of sphingolipids and are classified as long‐chain sphingoid bases. Sphingosine and sphinganine are known to play important roles in apoptosis. In the present study, we
Yukitoshi, Nagahara, Takahisa, Shinomiya, Sachiko, Kuroda, Naoki, Kaneko, Reiji, Nishio, Masahiko, Ikekita   +5 more
openaire   +2 more sources

Metabolites involved in cellular communication among human cumulus-oocyte-complex and sperm during in vitro fertilization [PDF]

, 2015
Background: Fertilization is a key physiological process for the preservation of the species. Consequently, different mechanisms affecting the sperm and the oocyte have been developed to ensure a successful fertilization. Thus, sperm acrosome reaction is
Avilés Sánchez, Manuel, Bernabeu, Rafael, García Hernández, Eva María, Gil-Izquierdo, Ángel, González-Brusi, Leopoldo, Guerrero, Jaime, Gómez-Torres, María José, Izquierdo-Rico, María José, Medina, Sonia, Orduna, Jesús, Savirón, María, Ten Morro, Jorge   +11 more
core   +6 more sources