Results 31 to 40 of about 5,394 (197)

Phytosphingosine promotes megakaryocytic differentiation of myeloid leukemia cells [PDF]

BMB Reports, 2015
We report that phytosphingosine, a sphingolipid found in many organisms and implicated in cellular signaling, promotes megakaryocytic differentiation of myeloid leukemia cells. Specifically, phytosphingosine induced several hallmark changes associated with megakaryopoiesis from K562 and HEL cells including cell cycle arrest, cell size increase and ...
Han, Sang Hee, Kim, Jusong, Her, Yerim, Seong, Ikjoo, Park, Sera, Bhattarai, Deepak, Jin, Guanghai, Lee, Kyeong, Chung, Gukhoon, Hwang, Sungkee, Bae, Yun Soo, Kim, Jaesang   +11 more
openaire   +3 more sources

A procedure for fractionation of sphingolipid classes by solid-phase extraction on aminopropyl cartridges

Journal of Lipid Research, 2000
Solid-phase extraction (SPE) methods are easy, rapid, and reliable. Their growing popularity is in part due to their operational simplicity and cost reduction in solvents, and partly because they are easier to automate.
J. Bodennec, O. Koul, I. Aguado, G. Brichon, G. Zwingelstein, J. Portoukalian   +5 more
doaj   +1 more source

Synthesis of C-5" and C-6"-modified α-GalCer analogues as iNKT-cell agonists [PDF]

, 2015
Alpha-Galactosyl Ceramide (α-GalCer) is a prototypical synthetic ligand of invariant natural killer T (iNKT) cells. Upon presentation by the MHC class I-like molecule CD1d, this glycolipid stimulates iNKT cells to secrete a vast amount of both pro ...
ASPESLAGH, SANDRINE, Elewaut, Dirk, Guillaume, Joren, Pauwels, Nora, Van Calenbergh, Serge, Zajonc, Dirk   +5 more
core   +1 more source

2,3-erythro-Dihydroxyhexacosanoic acid and homologs: isolation from yeast cerebrin phosphate and determination of their structures

Journal of Lipid Research, 1973
Homologs of methyl esters of very polar fatty acids were obtained by methanolysis of cerebrin phosphate isolated from baker's yeast. The major ester component was isolated by preparative gas–liquid chromatography and was found to be 2,3 ...
Motonori Hoshi, Yasuo Kishimoto, Charles Hignite   +2 more
doaj   +1 more source

Phytosphingosine-phosphate is a signal for AtMPK6 activation and Arabidopsis response to chilling [PDF]

, 2012
Long-chain bases (LCBs) are pleiotropic sphingolipidic signals in eukaryotes. We investigated the source and function of phytosphingosine-1-phosphate (PHS-P), a phospho-LCB rapidly and transiently formed in Arabidopsis thaliana on chilling.PHS-P was ...
Achard, Achard, Achard, Alain Zachowski, Alban Launay, Beckers, Cantrel, Chalfant, Chantal Demandre, Christelle Dutilleul, Coursol, Coursol, Cowart, Cuvillier, Emmanuel Baudouin, Fyrst, Ghouziel Benhassaine-Kesri, Guo, Hait, Ichimura, Imai, Isabelle Guillas, Jean-Pierre Renou, Kim, Lachaud, Li, Lieberherr, Lucki, Markham, Merrill, Michaelson, Nathalie Rézé, Ng, Nishikawa, Olsson, Pata, Peer, Ruelland, Ruelland, Sandra Pelletier, Saucedo-Garcia, Shi, Snider, Takemoto, Teige, Usadel, Vergnolle, Williams, Worrall, Zheng   +49 more
core   +4 more sources

Cyclophilin D links programmed cell death and organismal aging in Podospora anserina [PDF]

, 2018
This is the final version of the article. Available from Wiley via the DOI in this record.Cyclophilin D (CYPD) is a mitochondrial peptidyl prolyl-cis,trans-isomerase involved in opening of the mitochondrial permeability transition pore (mPTP).
Breunig, C, Brust, D, Daum, B, Hamann, A, Kühlbrandt, W, Osiewacz, HD   +5 more
core   +1 more source

Gas-chromatography/mass-spectrometry analysis of human skin constituents as heptafluorobutyrate derivatives with special reference to long-chain bases

Journal of Lipid Research, 2002
The composition of the constituents (monosaccharides, long-chain bases, and fatty acids) found in an ethanol extract of the human skin could be determined, without time-consuming steps of purification, after acid-catalyzed anhydrous methanolysis ...
Alexandre Pons, Philippe Timmerman, Yves Leroy, Jean-Pierre Zanetta   +3 more
doaj   +1 more source

O-Cyclic Phytosphingosine-1-Phosphate Protects against Motor Dysfunctions and Glial Cell Mediated Neuroinflammation in the Parkinson’s Disease Mouse Models

Antioxidants, 2022
O-cyclic phytosphingosine-1-phosphate (cPS1P) is a novel and chemically synthesized sphingosine metabolite derived from phytosphingosine-1-phosphate (S1P).
Hyeon Jin Lee, Kyonghwan Choe, Jun Sung Park, Amjad Khan, Min Woo Kim, Tae Ju Park, Myeong Ok Kim   +6 more
doaj   +1 more source

Phytoceramide Shows Neuroprotection and Ameliorates Scopolamine-Induced Memory Impairment

Molecules, 2011
The function and the role phytoceramide (PCER) and phytosphingosine (PSO) in the central nervous system has not been well studied. This study was aimed at investigating the possible roles of PCER and PSO in glutamate-induced neurotoxicity in cultured ...
Seikwan Oh, Jong Hoon Ryu, Sohyeon Moon, Jae-Chul Jung, Yeonju Lee   +4 more
doaj   +1 more source

Phytosphingosine inhibits cell proliferation by damaging DNA in human cell lines

Ecotoxicology and Environmental Safety, 2023
Harmful cyanobacterial blooms have caused numerous biosecurity incidents owing to the production of hazardous secondary metabolites such as microcystin. Additionally, cyanobacteria also release many other components that have not been explored.
Chunxiao Sun, Xuexiu Chang, Hugh J. MacIsaac, Jiayao Wen, Lixing Zhao, Zhi Dai, Jiaojiao Li   +6 more
doaj   +1 more source