Results 111 to 120 of about 901,118 (265)

P600: DNA METHYLATION ANALYSIS OF B-CELL PROLYMPHOCYTIC LEUKEMIA REVEALS TWO EPIGENETIC SUBTYPES WITH DISTINCT BIOLOGICAL AND CLINICAL FEATURES

HemaSphere, 2023
Stella Charalampopoulou, Elise Chapiro, Ferran Nadeu, Thorsten Zenz, Silvia Beà, Damien Roos-Weil, Olivier Bernard, Santos A Susin, Estella Matutes, Elias Campo, Martí Duran-Ferrer, Florence Nguyen-Khac, José Ignacio Martín-Subero   +12 more
doaj   +1 more source

Quality Assessment of Discarded Human Kidneys Using Normothermic Perfusion

Transplantation Direct
Background. Ex vivo normothermic perfusion (EVNP) allows for comprehensive functional assessment; however, current scoring systems are validated only for short perfusion durations.
Enrique Montagud-Marrahi, MD, PhD, Thomas Prudhomme, MD, PhD, Tarek Ajami, MD, Cristina García-Parejo, MD, Lluis Peri, MD, PhD, Adriana Rodriguez-Gonzalo, BSc, Yosu Luque, MD, PhD, Antoni Vilaseca, MD, PhD, Ruben Rabadan-Ros, PhD, Elena Cuadrado-Payan, MD, Elisenda Bañón-Maneus, PhD, Jordi Rovira, PhD, Maria José Ramírez-Bajo, PhD, Lourdes Mengual, PhD, Mercedes Ingelmo, PhD, Ana Belén Larque, MD, PhD, Antonio Alcaraz, MD, PhD, Josep M. Campistol, MD, PhD, Fritz Diekmann, MD, PhD, Mireia Musquera, MD, PhD   +19 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

PB2088: IMMUNE PROFILE OF PATIENTS WITH FOLLICULAR LYMPHOMA ASSESSED BY FLOW CYTOMETRY IN PERIPHERAL BLOOD: CHARACTERISTICS AT DIAGNOSIS AND AT RELAPSE OF THE DISEASE

HemaSphere, 2022
A. Rivero Arango, P. Mozas, J. Correa, A. Rivas-Delgado, F. Araujo-Ayala, K. Guinetti, A. Bataller, M. Condom, A. Gaya, J. Delgado, E. Giné, P. Perez-Galán, E. Campo, A. Vlagea, E. Matutes, A. López-Guillermo, N. Villamor, L. Magnano   +17 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

On Banach frameness of degenerate weighted exponential system

Fixed Point Theory and Algorithms for Sciences and Engineering
This work deals with the frameness of weighted exponential system E ( ω , Z ) = { ω ( t ) e i n t } n ∈ Z $E(\omega ,Z)= \left \{\omega (t)e^{int} \right \}_{n\in Z} $ in the space L p ( − π , π ) $L_{p} (-\pi ,\pi )$ , p > 1 $p>1$ , with the weight ...
Migdad I. Ismailov, Kader Simsir Acar
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A large Pi-1-2 set absolute for set forcing

, 1992
Let k be a definable L-cardinal. Then there is a set of reals X, class-generic over L, such that L(X) and L have the same cardinals, X has size k in L(X) and some pi-1-2 formula defines X in all set-generic extensions of L(X). Two corollaries, both assuming the consistency of an inaccessible: It is consistent for the Perfect Set Property to hold for ...
openaire   +2 more sources

Pi 1 Magnetic Pulsations Observed in Association with Low Latitude Aurora.

Journal of geomagnetism and geoelectricity, 1994
Irregular magnetic pulsations and IPDP plasma wave events related to the low latitude aurora were observed at Yonezawa observatory on October 20 and 21, 1989. Three positive bays appeared in the magnetograms on October 20. Concurrently, IPDP, Pi 2, Pi B and Pi C are registered during the respective positive bays.
openaire   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source