Results 151 to 160 of about 62,994 (190)

Distinct impact of PI(4)P flux on PI(4,5)P₂ steady states and oscillations. [PDF]

Proc Natl Acad Sci U S A
Xǔ XJ, Tong CS, Wu M.
europepmc   +1 more source

Synaptic transmission: Munc13 assembles onto PI(4,5)P₂-rich domains into trimers that cooperate to capture vesicles. [PDF]

Proc Natl Acad Sci U S A
Li F, Radhakrishnan A, Gautam S, Diaz G, Sundaram RVK, Coleman J, Zheng H, Grushin K, Chavent M, Rothman JE, Pincet F.   +10 more
europepmc   +1 more source

Enhanced channel activity by PI(4,5)P₂ ignites MLKL-related pathogenic processes. [PDF]

Cell Discov, 2022
Xia B, Qie J, Shen X, Wang S, Gao Z.
europepmc   +1 more source

A cell-permeable fluorescent probe reveals temporally diverse PI(4,5)P2 dynamics evoked by distinct GPCR agonists in neurons. [PDF]

Chem Sci
Kundu R, Mondal S, Kapadia A, Banerjee AA, Kucherak OA, Klymchenko AS, Koushika SP, Venkatramani R, Vaidya VA, Datta A.   +9 more
europepmc   +1 more source

A phosphoinositide switch from PI(4,5)P₂ to PI4P triggers endocytosis by inducing dynamin-mediated fission in secretory cells. [PDF]

Sci Adv
Guo X, Wei L, Kundu N, Shin W, Chan CY, Han S, Mohseni A, Molakarimi M, Sun M, Wu XS, Jin Y, Hinshaw JE, Wu LG.   +12 more
europepmc   +1 more source

Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P₂ hydrolysis in the plasma membrane. [PDF]

J Biol Chem, 2023
Chen H, Lu C, Tan Y, Weber-Boyvat M, Zheng J, Xu M, Xiao J, Liu S, Tang Z, Lai C, Li M, Olkkonen VM, Yan D, Zhong W.   +13 more
europepmc   +1 more source

PI(4,5)P₂-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling. [PDF]

Sci Signal, 2022
Mahoney JP, Bruguera ES, Vasishtha M, Killingsworth LB, Kyaw S, Weis WI.   +5 more
europepmc   +1 more source

Influence of Cholesterol on PI(4,5)P2 Clustering in Model Membranes

Biophysical Journal, 2019
Kyungreem Han, Anne-Marie Byrant, Richard M. Venable, Arne Gericke, Richard W. Pastor   +4 more
openaire   +1 more source

Rezeptorinduzierte PI(4,5)P2-Dynamik in hippocampalen CA1-Pyramidenneuronen

, 2014
Das Plasmamembranlipid Phosphatidylinositol(4,5)biphosphat (PIP2) ist an der Regulation einer Vielzahl zellularer Prozesse beteiligt. Die Dynamik der PIP2-Konzentration in lebenden Zellen in ihrer nativen Umgebung ist bislang allerdings weitgehend unerforscht.
openaire   +2 more sources

Nonsubstrate PI(4,5)P₂ interacts with the interdomain linker to control electrochemical coupling in voltage-sensing phosphatase (VSP). [PDF]

Proc Natl Acad Sci U S A
Mizutani N, Yonezawa Y, Nakagawa A, Okamura Y.   +3 more
europepmc   +1 more source