Protective Effect of Anti-Phosphatidylserine Antibody in a Guinea Pig Model of Advanced Hemorrhagic Arenavirus Infection [PDF]
, 2017 Objective: Host derived markers on virally infected cells or virions may provide targets for the generation of antiviral agents. Recently, we identified phosphatidylserine (PS) as a host marker of virions and virally-infected cells. Methods and Materials:
Thomas, John M., Thorpe, Philip E.
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Expression and Purification of Z Protein from Junín Virus
BioMed Research International, Volume 2010, Issue 1, 2010., 2010 Arenaviridae comprises 23 recognized virus species with a bipartite ssRNA genome and an ambisense coding strategy. The virions are enveloped and include nonequimolar amounts of each genomic RNA species, designated L and S, coding for four ORFs (N, GPC, L, and Z).
S. E. Goñi +11 more
wiley +1 more source
A Systems Biology Starter Kit for Arenaviruses
Viruses, 2012 Systems biology approaches in virology aim to integrate viral and host biological networks, and thus model the infection process. The growing availability of high-throughput “-omics” techniques and datasets, as well as the ever ...
Magali E. Droniou-Bonzom +1 more
doaj +1 more source
Evaluation of Protective Efficacy of Viral Vector Based Swine Influenza Vaccine and a Method for B Cell Culture for Monoclonal Antibody Generation [PDF]
, 2022 Influenza A virus of the swine (IAV-S) is an economically important swine pathogen that has the potential to spread to humans, thus posing an ongoing public health concern due to its zoonotic potential.
Kumari, Sushmita
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Variation Between Strains of Hamsters in the Lethality of Pichinde Virus Infections [PDF]
Infection and Immunity, 1977 Infection by Pichinde virus, a member of the arenavirus group, was studied in Golden Syrian hamsters ( Mesocricetus auratus ) with regard to possible mechanisms of resistance to virus infection in adult hamsters. Two hamster strains were found to differ in their susceptibility to lethal Pichinde virus infection. LVG/
M J, Buchmeier, W E, Rawls
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, 2015 BioMed Research International, Volume 2015, Issue 1, 2015.
Joseph W. Golden +3 more
wiley +1 more source
Viral Infection: A Potent Barrier to Transplantation Tolerance
Journal of Immunology Research, Volume 2008, Issue 1, 2008., 2008 Transplantation of allogeneic organs has proven to be an effective therapeutic for a large variety of disease states, but the chronic immunosuppression that is required for organ allograft survival increases the risk for infection and neoplasia and has direct organ toxicity.
David M. Miller +4 more
wiley +1 more source
Use of recombinant adenovirus vectored consensus IFN-α to avert severe arenavirus infection.
PLoS ONE, 2011 Several arenaviruses can cause viral hemorrhagic fever, a severe disease with case-fatality rates in hospitalized individuals ranging from 15-30%. Because of limited prophylaxis and treatment options, new medical countermeasures are needed for these ...
Brian B Gowen +5 more
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Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus. [PDF]
, 1990 Intracellular events in the synthesis, glycosylation, and transport of the lymphocytic choriomeningitis virus (LCMV) glycoproteins have been examined. We have shown by N-glycanase digestion that LCMV strain Arm-4 bears five oligosaccharides on GP-1 and ...
Buchmeier, MJ +3 more
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Die Rolle des Signalpeptids für die Reifung des Lassavirus Glykoproteins [PDF]
, 2004 Das Oberflächenglykoprotein des Lassavirus ist ein Typ 1-Membranprotein. Es wird als Vorläufer präGP-C synthetisiert und posttranslational mit N-Glykanen modifiziert.
Buckel, Wolfgang (Prof. Dr.) +1 more
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