Results 51 to 60 of about 1,551 (170)
Fine Structure Analysis of Pichinde Virus Nucleocapsids
Journal of General Virology, 1983 The structure and organization of the ribonucleoprotein (RNP) complex of an arenavirus, Pichinde virus, was investigated. The basic configuration of the RNP was found to be a linear array of globular subunits or nucleosomes, 4 to 5 nm in diameter, that represent individual molecules of the major N polypeptide.
Young, PR, Howard, CR
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Biomédica: revista del Instituto Nacional de Salud, 2017 Introducción. El virus de la coriomeningitis linfocítica es un arenavirus del Viejo Mundo que se hospeda en el ratón casero (Mus musculus), y puede causar infecciones congénitas, hidrocefalia, coriorretinitis y falla orgánica múltiple en pacientes ...
Anais Castellar +7 more
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Arenavirus budding resulting from viral-protein-associated cell membrane curvature [PDF]
, 2013 Viral replication occurs within cells, with release (and onward infection) primarily achieved through two alternative mechanisms: lysis, in which virions emerge as the infected cell dies and bursts open; or budding, in which virions emerge gradually from
Abelson HT +18 more
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Inhibition of Pichinde Virus Replication by Actinomycin D
Journal of General Virology, 1976 The yields of Pichinde virus, a member of the arenavirus group, were markedly inhibited when infected BHK 21 cells were incubated in the presence of 0.4 to 4 mug/ml of actinomycin D. Maximal inhibition was observed when actinomycin D was added after the adsorption of virus to cultures; however, addition of drug as late as 12 h after infection reduced ...
W E, Rawls +3 more
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Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015 Ebola virus is responsible for causing severe hemorrhagic fevers, with case fatality rates of up to 90%. Currently, no antiviral or vaccine is licensed against Ebola virus. A phosphatidylserine‐targeting antibody (PGN401, bavituximab) has previously been shown to have broad‐spectrum antiviral activity.
S. D. Dowall +8 more
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Isolation of Ribosome-like Structures from Pichinde Virus
Journal of General Virology, 1975 Three classes of mamalian ribosome-like structures were found to be associated with purified Pichinde virus preparations. These structures, possessing sedimentation coefficients of 80S, 60S and 40S, were sensitive to EDTA dissociation and possessed a buoyant density in caesium chloride of 1-61 g/ml, a value analogous to that displayed by BHK21 cell ...
F E, Farber, W E, Rawls
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, 2022 Journal of the International AIDS Society, Volume 25, Issue S3, August 2022.
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Animal Models for the Study of Rodent‐Borne Hemorrhagic Fever Viruses: Arenaviruses and Hantaviruses
BioMed Research International, Volume 2015, Issue 1, 2015., 2015 Human pathogenic hantaviruses and arenaviruses are maintained in nature by persistent infection of rodent carrier populations. Several members of these virus groups can cause significant disease in humans that is generically termed viral hemorrhagic fever (HF) and is characterized as a febrile illness with an increased propensity to cause acute ...
Joseph W. Golden +4 more
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The future of antiviral immunotoxins [PDF]
, 2016 There is a constant need for new therapeutic interventions in a wide range of infectious diseases. Over the past few years, the immunotoxins have entered the stage as promising antiviral treatments.
Høy Jakobsen, Mette +3 more
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The Regulatory Role of Activating Transcription Factor 2 in Inflammation
Mediators of Inflammation, Volume 2014, Issue 1, 2014., 2014 Activating transcription factor 2 (ATF2) is a member of the leucine zipper family of DNA‐binding proteins and is widely distributed in tissues including the liver, lung, spleen, and kidney. Like c‐Jun and c‐Fos, ATF2 responds to stress‐related stimuli and may thereby influence cell proliferation, inflammation, apoptosis, oncogenesis, neurological ...
Tao Yu +14 more
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