Results 31 to 40 of about 1,551 (170)

Enhancing the use of T cells as a universal preventive measure against H3N2 influenza: Mechanism and implications. [PDF]

open access: yesHealth Sci Rep
Health Science Reports, Volume 7, Issue 8, August 2024.
Bhatt JH   +4 more
europepmc   +2 more sources

Polymerase Activity of Pichinde Virus [PDF]

open access: yesJournal of Virology, 1974
Pichinde virus, a member of the arenavirus group, was examined for polymerase activity. Purified virus was found to contain RNA-dependent RNA polymerase but not RNA-dependent DNA polymerase activity. Since RNase but neither DNase nor actinomycin D inhibited the endogenous polymerase reaction, RNA of the virus appeared to be used as the ...
M F, Carter, N, Biswal, W E, Rawls
openaire   +2 more sources

Observation of arenavirus nucleoprotein heptamer assembly

open access: yesFEBS Open Bio, Volume 11, Issue 4, Page 1076-1083, April 2021., 2021
The nucleoprotein associates with RNA to form a ribonucleoprotein complex. The nucleoprotein trends to self‐assemble into heptameric rings. Theses rings represent stable intermediate states representative of the average full turn of the Arenaviridae ribonucleoprotein filament.
Nicolas Papageorgiou   +6 more
wiley   +1 more source

Viral MicroRNA Effects on Pathogenesis of Polyomavirus SV40 Infections in Syrian Golden Hamsters [PDF]

open access: yes, 2014
Shaojie Zhang, Vojtech Sroller, Preeti Zanwar, Steven J. Halvorson, Nadim J. Ajami, Corey W. Hecksel, Jody L. Swain, Connie Wong, Janet S. Butel, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States
Ajami, Nadim J.   +10 more
core   +11 more sources

Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope. [PDF]

open access: yesPLoS Pathogens, 2012
T cell cross-reactivity between different strains of the same virus, between different members of the same virus group, and even between unrelated viruses is a common occurrence.
Alex T Chen   +9 more
doaj   +1 more source

Structural Proteins of Pichinde Virus [PDF]

open access: yesJournal of Virology, 1972
Pichinde virus, a member of the arenovirus group, was found to have four polypeptides by polyacrylamide gel electrophoresis. Two components, V I and V II , had molecular weights of about 72,000, whereas V III had a molecular weight of 34,000. A minor component, V
B A, Ramos, R J, Courtney, W E, Rawls
openaire   +2 more sources

Characterization of Nucleic Acid of Pichinde Virus [PDF]

open access: yesJournal of Virology, 1973
The nucleic acid of Pichinde virus was found to be single-stranded ribonucleic acid (RNA) as determined by sensitivity to ribonuclease, by alkaline degradation, by buoyant density in cesium sulfate, and by analysis of the base composition.
M F, Carter, N, Biswal, W E, Rawls
openaire   +2 more sources

Arenaviruses: Old viruses present new solutions for cancer therapy

open access: yesFrontiers in Immunology, 2023
Viral-based cancer therapies have tremendous potential, especially in the context of treating poorly infiltrated cold tumors. However, in tumors with intact anti-viral interferon (IFN) pathways, while some oncolytic viruses induce strong innate and ...
Paweł Stachura   +5 more
doaj   +1 more source

How age and infection history shape the antigen‐specific CD8+ T‐cell repertoire: Implications for vaccination strategies in older adults

open access: yesAging Cell, Volume 19, Issue 11, November 2020., 2020
In this review, we aim to provide insight in the maintenance of antigen‐experienced CD8+ T‐cell clones during life. We describe what is already known on the effect of age on the virus‐specific T‐cell repertoire and discuss the contribution of infection history in shaping the repertoire.
Josien Lanfermeijer   +2 more
wiley   +1 more source

Analysis of the Cell Type-Dependence on the Arenavirus Z-Mediated Virus-Like Particle Production

open access: yesFrontiers in Microbiology, 2020
Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidated ...
Patrick I. Mpingabo   +6 more
doaj   +1 more source

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