Results 31 to 40 of about 979 (130)
Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever
Virology Journal, 2010 Background A number of RNA viruses cause viral hemorrhagic fever (VHF), in which proinflammatory mediators released from infected cells induce increased permeability of the endothelial lining of blood vessels, leading to loss of plasma volume ...
Morrey John D +7 more
doaj +1 more source
T cells in the brain enhance neonatal mortality during peripheral LCMV infection.
PLoS Pathogens, 2021 In adult mice the severity of disease from viral infections is determined by the balance between the efficiency of the immune response and the magnitude of viral load. Here, the impact of this dynamic is examined in neonates.
Laurie L Kenney +3 more
doaj +1 more source
Pseudotypes of Vesicular Stomatitis Virus and Pichinde Virus
Journal of General Virology, 1979 Super-infection of Pichinde virus-infected cells with vesicular stomatitis virus (VSV) resulted in the production of pseudotype virus which was not neutralized by antiserum to VSV but which was neutralized by antiserum to Pichinde virus. Analysis of pseudotype virus production in relation to the kinetics of replication of Pichinde virus demonstrated ...
S, Sengupta, W E, Rawls
openaire +2 more sources
Frontiers in Immunology, 2023 IntroductionTuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains a major global health threat. The only available vaccine Bacille Calmette-Guérin (BCG) does not prevent adult pulmonary TB. New effective TB vaccines should aim to stimulate
Natalie M. Kirk +10 more
doaj +1 more source
Serological Evidence of Infection by Pichinde Virus Among Laboratory Workers [PDF]
Infection and Immunity, 1974 A total of 44 laboratory workers were examined for serological evidence of infection by Pichinde virus. Complement-fixing antibodies were detected in the sera of 6 of 13 (46%) persons working with the virus but not among 31 persons not working with the virus.
M, Buchmeier, E, Adam, W E, Rawls
openaire +2 more sources
Biomédica: revista del Instituto Nacional de Salud, 2017 Introducción. El virus de la coriomeningitis linfocítica es un arenavirus del Viejo Mundo que se hospeda en el ratón casero (Mus musculus), y puede causar infecciones congénitas, hidrocefalia, coriorretinitis y falla orgánica múltiple en pacientes ...
Anais Castellar +7 more
doaj +1 more source
Effects of Actinomycin D and Ultraviolet and Ionizing Radiation on Pichinde Virus [PDF]
Journal of Virology, 1973 Actinomycin D (0.05 μg/ml) suppresses the synthesis of ribosomal RNA of baby hamster kidney (BHK21) cells. The production of infectious Pichinde virus was enhanced in the presence of actinomycin D, although the production of virus particles was not substantially different from cultures inoculated in the absence of the drug.
M F, Carter +4 more
openaire +2 more sources
Inhibition of Pichinde Virus Replication by Actinomycin D
Journal of General Virology, 1976 The yields of Pichinde virus, a member of the arenavirus group, were markedly inhibited when infected BHK 21 cells were incubated in the presence of 0.4 to 4 mug/ml of actinomycin D. Maximal inhibition was observed when actinomycin D was added after the adsorption of virus to cultures; however, addition of drug as late as 12 h after infection reduced ...
W E, Rawls +3 more
openaire +2 more sources
Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015 Ebola virus is responsible for causing severe hemorrhagic fevers, with case fatality rates of up to 90%. Currently, no antiviral or vaccine is licensed against Ebola virus. A phosphatidylserine‐targeting antibody (PGN401, bavituximab) has previously been shown to have broad‐spectrum antiviral activity.
S. D. Dowall +8 more
wiley +1 more source
, 2022 Journal of the International AIDS Society, Volume 25, Issue S3, August 2022.
wiley +1 more source