Results 41 to 50 of about 1,551 (170)
Serological Evidence of Infection by Pichinde Virus Among Laboratory Workers [PDF]
Infection and Immunity, 1974 A total of 44 laboratory workers were examined for serological evidence of infection by Pichinde virus. Complement-fixing antibodies were detected in the sera of 6 of 13 (46%) persons working with the virus but not among 31 persons not working with the virus.
M, Buchmeier, E, Adam, W E, Rawls
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Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever. [PDF]
PLoS Neglected Tropical Diseases, 2011 Lassa and Junín viruses are the most prominent members of the Arenaviridae family of viruses that cause viral hemorrhagic fever syndromes Lassa fever and Argentine hemorrhagic fever, respectively.
Michelle Mendenhall +6 more
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Frontiers in Oncology, 2021 Engineered viral vectors represent a promising strategy to trigger antigen-specific antitumor T cell responses. Arenaviruses have been widely studied because of their ability to elicit potent and protective T cell responses.
Henning Lauterbach +14 more
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T cells in the brain enhance neonatal mortality during peripheral LCMV infection.
PLoS Pathogens, 2021 In adult mice the severity of disease from viral infections is determined by the balance between the efficiency of the immune response and the magnitude of viral load. Here, the impact of this dynamic is examined in neonates.
Laurie L Kenney +3 more
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Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever
Virology Journal, 2010 Background A number of RNA viruses cause viral hemorrhagic fever (VHF), in which proinflammatory mediators released from infected cells induce increased permeability of the endothelial lining of blood vessels, leading to loss of plasma volume ...
Morrey John D +7 more
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Functional complementation between FADD and RIP1 in embryos and lymphocytes. [PDF]
, 2011 FADD is a common adaptor shared by several death receptors for signalling apoptosis through recruitment and activation of caspase 8 (refs 1-3). Death receptors are essential for immune homeostasis, but dispensable during embryogenesis. Surprisingly, Fadd(
Chan, Francis Ka-Ming +5 more
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Frontiers in Immunology, 2023 IntroductionTuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains a major global health threat. The only available vaccine Bacille Calmette-Guérin (BCG) does not prevent adult pulmonary TB. New effective TB vaccines should aim to stimulate
Natalie M. Kirk +10 more
doaj +1 more source
Direct observation of membrane insertion by enveloped virus matrix proteins by phosphate displacement [PDF]
, 2013 Enveloped virus release is driven by poorly understood proteins that are functional analogs of the coat protein assemblies that mediate intracellular vesicle trafficking.
Al-Mulla, Hawaa M. N +7 more
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Pseudotypes of Vesicular Stomatitis Virus and Pichinde Virus
Journal of General Virology, 1979 Super-infection of Pichinde virus-infected cells with vesicular stomatitis virus (VSV) resulted in the production of pseudotype virus which was not neutralized by antiserum to VSV but which was neutralized by antiserum to Pichinde virus. Analysis of pseudotype virus production in relation to the kinetics of replication of Pichinde virus demonstrated ...
S, Sengupta, W E, Rawls
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Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]
, 2010 Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel +16 more
core +1 more source