Results 51 to 60 of about 5,118,399 (260)

Carboxylic Solvents and O-Donor Ligand Effects on CH Activation by Pt(II) [PDF]

, 2006
We report on the design of more efficient C−H activation catalysts based on DFT calculations. The first examples of well-defined, N,O-donor ligated platinum complexes that are competent for fast C−H activation are detailed.
Goddard, William A., III, Mironov, Oleg A., Oxgaard, Jonas, Periana, Roy A., Young, Kenneth J. H., Ziatdinov, Vadim R.   +5 more
core   +1 more source

Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect

Journal of Child Psychology and Psychiatry, EarlyView.
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson, Hanna R. Wright, Jorden E. Jacinto Schreeder, Joel T. Nigg, Elinor L. Sullivan   +4 more
wiley   +1 more source

Speciation of metal complexes of medicinal interest: relationship between solution equilibria and pharmaceutical properties [PDF]

, 2018
Biospeciation of essential and toxic metal ions, metal complexes with biological or medicinal activity are discussed in the paper in order to emphasize the importance of the distribution of metal ions in biological milieu.
Dömötör, Orsolya, Enyedy, Éva Anna, Jakusch, Tamás, Kiss, Tamás   +3 more
core   +2 more sources

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, Volume 16, Issue 1, Page 52-67, January 2026.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Alleviative effect of Lueyang black-bone chicken liver peptides on dextran sodium sulfate-induced ulcerative colitis in mice

Journal of Functional Foods
Ulcerative colitis (UC), an inflammatory bowel disease with long-term medication side effects, requires safe therapies. Lueyang black-bone chicken liver peptides (BLP) were prepared by hydrolyzing its liver with 1 % alkaline protease for 1 h.
Jincheng Xi, Shanshan Wang, Ruixue Wang, Ling Wang, Hongzhao Lu, Tao Zhang, Wenxian Zeng   +6 more
doaj   +1 more source

Sustained and Efficient Ethanol Oxidation by Tethering Tunable N‐Donors Onto Integrated MXene/Pd‐Electrodes

Advanced Science, Volume 13, Issue 2, 9 January 2026.
Three novel 3D layered integrated electrodes for Pd‐catalysed ethanol oxidation are developed; their innovative design features N‐heterocyclic amide linkers grafted on an MXene, co‐anchoring Pd nanoparticles via “hand‐in‐hand” coordination. The resulting well‐defined Pd (111) catalytic sites help achieve extremely stable long‐term cycling with ...
Zhangxin Chen, Fan Jing, Alexandros Terzopoulos, Yanxian Jin, Kai Huang, Haichang Fu, Na Liu, Xianqiang Xiong, Binbin Yu, Dan Chen, Yang Xia, Dominic S. Wright   +11 more
wiley   +1 more source

Pyrazinoic acid, the active form of the anti-tuberculosis drug pyrazinamide, and aromatic carboxylic acid analogs are protonophores

Frontiers in Molecular Biosciences
Pyrazinoic acid is the active form of pyrazinamide, a first-line antibiotic used to treat Mycobacterium tuberculosis infections. However, the mechanism of action of pyrazinoic acid remains a subject of debate, and alternatives to pyrazinamide in cases of
Fabio L. Fontes, Fabio L. Fontes, Steven A. Rooker, Jamie K. Lynn-Barbe, Michael A. Lyons, Debbie C. Crans, Debbie C. Crans, Dean C. Crick, Dean C. Crick   +8 more
doaj   +1 more source

The kynurenine pathway and the brain: challenges, controversies and promises [PDF]

, 2017
Research on the neurobiology of the kynurenine pathway has suffered years of relative obscurity because tryptophan degradation, and its involvement in both physiology and major brain diseases, was viewed almost exclusively through the lens of the well ...
Schwarcz, Robert, Stone, Trevor W.
core   +1 more source

Mn2+ Bispidine Complexes as Potential Magnetic Resonance Imaging Agents : Noncoordinating Peripheral Functional Groups Affect Structural, Kinetic, and Relaxation Properties

ChemistryEurope, Volume 4, Issue 1, January 2026.
In the family of Mn2+ complexes formed with pentadentate bispidine chelates, functional groups that do not interfere with metal coordination can play a significant role in enhancing kinetic inertness and proton relaxation efficacy. Mn2+ bispidine complexes combine unprecedented kinetic inertness with high relaxivity and are under scrutiny as potential ...
Maryame Sy, Daouda Ndiaye, Hervé Meudal, Loïc J. Charbonnière, Aline M. Nonat, Éva Tóth   +5 more
wiley   +1 more source

Investigation of Pyridine Carboxylic Acids in CM2 Carbonaceous Chondrites: Potential Precursor Molecules for Ancient Coenzymes [PDF]

The distribution and abundances of pyridine carboxylic acids (including nicotinic acid) in eight CM2 carbonaceous chondrites (ALH 85013, DOM 03183, DOM 08003, EET 96016, LAP 02333, LAP 02336, LEW 85311, and WIS 91600) were investigated by liquid ...
Callahan, Michael P., Dworkin, Jason P., Gerakines, Perry A., House, Christopher H., Smith, Karen E.   +4 more
core   +4 more sources