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Selective inhibitors of picornavirus replication
Medicinal Research Reviews, 2008AbstractPicornaviruses cover a large family of pathogens that have a major impact on human but also on veterinary health. Although most infections in man subside mildly or asymptomatically, picornaviruses can also be responsible for severe, potentially life‐threatening disease.
Armando M, De Palma +3 more
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Picornavirus-like Structures in Acute Dermatomyositis
American Journal of Clinical Pathology, 1972A case of acute fatal dermatomyositis occurring in a young girl is described. Clinically, there was pronounced involvement of the striated muscles, skin, and brain. The patient died 11 weeks after acute symptoms began. Histologically, there was a marked myositis, with atrophy of muscle fibers, myolysis, and mononuclear infiltrates. Examination with the
M, Ben-Bassat, I, Machtey
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Picornavirus Structure Overview
2014In many cases, structures have been determined, often using the lower resolution cryo-electron microscopy (cryo-EM) technique, of picornaviruses in complex with their cellular receptors, neutralizing antibodies, antiviral compounds, or other, biologically significant ligands.
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Picornavirus Genetics: an Overview
2014This chapter overviews the mechanisms underlying the stability and especially the variability of the picornavirus phenotype and genotype. It also talks about the principles of genetic analysis of viral functions and of manipulations with the viral genome.
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