Results 51 to 60 of about 971 (157)

Saffron Alters Microbial Amino Acid Metabolism and Neurotransmitter Production in a Defined Gut Consortium

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Graphical representation of the metabolic pathways modulated by saffron within defined microbial communities. In the tryptophan pathway, saffron decreased levels of tryptophan and anthranilic acid while increasing concentrations of indole‐3‐acetic acid and tryptamine.
Adelaide E. Horvath, Makenna Grozis, Paul R. S. Baker, Santosh Kapil Kumar Gorti, Robert Proos, Ahmad Imran, Hassan Brim, Thomas D. Horvath, Melinda A. Engevik, Hassan Ashktorab   +9 more
wiley   +1 more source

Oral Administration of Crocus sativus Tepals Extract Restores High‐Fat Diet‐Induced Gut Dysbiosis and Modulates Intestinal Inflammation and Hepatic Lipid Metabolism

BioFactors, Volume 52, Issue 1, January/February 2026.
This study shows that oral administration of Crocus sativus tepals extract (CTE) restores gut microbiota composition and promotes SCFA‐producing and anti‐inflammatory bacterial genera. It improves intestinal barrier integrity and reduces inflammation in the jejunum and liver, suggesting a possible link between the gut microbiota and the metabolic ...
Biljana Bursać, Miloš Vratarić, Ljupka Gligorovska, Luisa Bellachioma, Ana Teofilović, Danijela Vojnović Milutinović, Camilla Morresi, Elisabetta Damiani, Tiziana Bacchetti, Ana Djordjevic   +9 more
wiley   +1 more source

UGT709G1: a novel uridine diphosphate glycosyltransferase involved in the biosynthesis of picrocrocin, the precursor of safranal in saffron (Crocus sativus)

New Phytologist, 2019
Summary Saffron, a spice derived from the dried red stigmas of Crocus sativus, is one of the oldest natural food additives. The flowers have long red stigmas, which store significant quantities of the glycosylated apocarotenoids crocins and picrocrocin. The apocarotenoid biosynthetic pathway in saffron starts with the oxidative cleavage of zeaxanthin,
Gianfranco Diretto, Oussama Ahrazem, Ángela Rubio‐Moraga, Alessia Fiore, Filippo Sevi, Javier Argandoña, Lourdes Gómez‐Gómez   +6 more
openaire   +3 more sources

Eco‐Friendly ZnO–Chitosan Nanocomposite‐Embedded Sodium Alginate/Polyvinyl Alcohol/Saffron Hydrogel for Enhanced Antibacterial Applications

IET Nanobiotechnology, Volume 2026, Issue 1, 2026.
This study reports the green synthesis, development, and characterization of novel eco‐friendly zinc oxide nanoparticles (ZnO NPs) coated with chitosan (ZnO NPs–Chsn) and their incorporation into a polyvinyl alcohol/sodium alginate/saffron (PSS) hydrogel for enhanced antibacterial applications. ZnO NPs were biosynthesized using quince (Cydonia oblonga)
Fatemeh Karampour, Saba Zendehcheshm, Nour El-Gendy   +2 more
wiley   +1 more source

Quality traits of saffron (Crocus sativus L.) produced in the Italian Alps

Open Agriculture, 2017
Saffron (Crocus sativus L.) is a perennial herbaceous geophyte in the Iridaceae family. It propagates vegetatively by corm. All saffron production processes are generally conducted by hand: from bulb implantation, harvesting of flowers to stigma ...
Giorgi Annamaria, Pentimalli Daniela, Giupponi Luca, Panseri Sara   +3 more
doaj   +1 more source

Determination of Saffron Flower Metabolites by Near-Infrared Spectroscopy for Quality Control

Horticulturae
Saffron, obtained by dehydrating the stigmas of the Crocus sativus flower, is a spice of great importance. In saffron, the flower emerges before leaf formation, thanks to the nutritional reserves of the corm.
Jorge F. Escobar-Talavera, María Esther Martínez-Navarro, Gonzalo L. Alonso, Rosario Sánchez-Gómez   +3 more
doaj   +1 more source

A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease

Acta Ophthalmologica, Volume 103, Issue 6, Page e346-e363, September 2025.
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia, José Manuel Benítez del Castillo, Margarita Calonge, Christophe Baudouin, Marc Labetoulle   +4 more
wiley   +1 more source

Saffron Cultivation in Marginal Alpine Environments: How AMF Inoculation Modulates Yield and Bioactive Compounds

Agronomy, 2018
Arbuscular mycorrhizal fungi (AMF) establish mutualistic symbiotic associations with plant roots and act as biofertilizers by enhancing plant nutrient and water uptake.
Matteo Caser, Íris Marisa Maxaieie Victorino, Sonia Demasi, Andrea Berruti, Dario Donno, Erica Lumini, Valeria Bianciotto, Valentina Scariot   +7 more
doaj   +1 more source

Monochromatic blue light enhances crocin and picrocrocin content by upregulating the expression of underlying biosynthetic pathway genes in saffron (Crocus sativus L.)

Frontiers in Horticulture, 2022
Saffron quality is determined by the content of three apocarotenoids, including crocin, picrocrocin, and safranal, giving saffron culinary, industrial, and medical importance. The level of these secondary metabolites is also affected by environmental factors such as light, which play a pivotal role in regulating plants' signaling pathways.
Moradi, Shirin, Kafi, Mohsen, Aliniaeifard, Sasan, Moosavi-Nezhad, Moein, Pedersen, Carsten, Gruda, Nazim S., Salami, Seyed Alireza   +6 more
openaire   +2 more sources

Rapid isolation and characterization of crocins, picrocrocin, and crocetin from saffron using centrifugal partition chromatography and LC–MS

Journal of Separation Science, 2018
AbstractThis study demonstrates a simple method for one‐step isolation of the main secondary metabolites of a hydroalcoholic extract of Crocus sativus stigmas (saffron) using step‐gradient centrifugal partition chromatography. The analysis was performed in dual and elution−extrusion mode, using five biphasic systems of the solvents heptane/ethyl ...
Evangelia Karkoula, Apostolis Angelis, Nikolaos‐Stavros Koulakiotis, Evangelos Gikas, Maria Halabalaki, Anthony Tsarbopoulos, Alexios‐Leandros Skaltsounis   +6 more
openaire   +3 more sources