Results 31 to 40 of about 4,014 (160)

Downregulation of in the Detrusor of Men With Bladder Outlet Obstruction and Its Association With Urinary Retention and Decreased Bladder Compliance [PDF]

open access: yesInternational Neurourology Journal
Purpose Recent research has highlighted the mechanotransducer PIEZO2 as a crucial factor in lower urinary tract function, demonstrating associations with bladder compliance (BC), bladder wall thickening, and elevated bladder pressure.
Carlos Henrique Suzuki Bellucci   +11 more
doaj   +1 more source

Delayed Onset Muscle Soreness and Critical Neural Microdamage-Derived Neuroinflammation

open access: yesBiomolecules, 2022
Piezo2 transmembrane excitatory mechanosensitive ion channels were identified as the principal mechanotransduction channels for proprioception. Recently, it was postulated that Piezo2 channels could be acutely microdamaged on an autologous basis at ...
Balázs Sonkodi
doaj   +1 more source

Mechano-Sensing Channel PIEZO2 Enhances Invasive Phenotype in Triple-Negative Breast Cancer [PDF]

open access: yes, 2022
Background: Mechanically gated PIEZO channels lead to an influx of cations, activation of additional Ca2+ channels, and cell depolarization. This study aimed to investigate PIEZO2’s role in breast cancer.
Arnaldo Mercado-Perez   +17 more
core   +1 more source

Touching upon regulators of Piezo2 in mouse somatosensation [PDF]

open access: yes, 2017
Mechanosensation is an integral property of sensory systems like audition and somatosensation. The molecular determinants of mechanotransduction in mammals are only beginning to be understood. In 2010, Piezo2, a member of the Piezo family, was identified
Narayanan, P., Narayanan, Pratibha
core   +1 more source

Parameters of Piezo2 channels.

open access: yes, 2023
Merkel cells combine with Aβ afferents, producing slowly adapting type 1(SA1) responses to mechanical stimuli. However, how Merkel cells transduce mechanical stimuli into neural signals to Aβ afferents is still unclear.
Wenzhen Yang (4093081)   +1 more
core   +1 more source

Electroacupuncture Attenuates Post-Inflammatory IBS-Associated Visceral and Somatic Hypersensitivity and Correlates With the Regulatory Mechanism of Epac1–Piezo2 Axis

open access: yesFrontiers in Endocrinology, 2022
Electroacupuncture (EA) is considered to have a therapeutic effect in the relief of irritable bowel syndrome (IBS)-associated visceral hypersensitivity via the reduction of the level of 5‐hydroxytryptamine (5‐HT) and 5-HT3 receptors (5-HT3R).
Jing Guo   +12 more
doaj   +1 more source

Piezo2 voltage-block regulates mechanical pain sensitivity [PDF]

open access: yes
PIEZO2 is a trimeric mechanically-gated ion channel expressed by most sensory neurones in the dorsal root ganglia. Mechanosensitive PIEZO2 channels are also genetically required for normal touch sensation in both mice and humans.
García-Contreras, J.A.   +7 more
core   +1 more source

DataSheet2_A pan-cancer analysis reveals the genetic alterations and immunotherapy of Piezo2 in human cancer.PDF

open access: yes, 2022
Background: Piezo2 is a transmembrane-spanning ion channel protein implicated in multiple physiological processes, including cell proliferation and angiogenesis in many cell types.
Yangpu Jia (13196634)   +4 more
core   +1 more source

Table1_A pan-cancer analysis reveals the genetic alterations and immunotherapy of Piezo2 in human cancer.XLSX

open access: yes, 2022
Background: Piezo2 is a transmembrane-spanning ion channel protein implicated in multiple physiological processes, including cell proliferation and angiogenesis in many cell types.
Yangpu Jia (13196634)   +4 more
core   +1 more source

DataSheet1_A pan-cancer analysis reveals the genetic alterations and immunotherapy of Piezo2 in human cancer.PDF

open access: yes, 2022
Background: Piezo2 is a transmembrane-spanning ion channel protein implicated in multiple physiological processes, including cell proliferation and angiogenesis in many cell types.
Yangpu Jia (13196634)   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy