Results 41 to 50 of about 4,014 (160)
Molecular Brain, 2023 Unraveling the intricate relationship between mechanical factors and brain activity is a pivotal endeavor, yet the underlying mechanistic model of signaling pathways in brain mechanotransduction remains enigmatic.
Arjun Raha +8 more
doaj +1 more source
Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia
Advanced Science, EarlyView.Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li +8 more
wiley +1 more source
Piezo2 channels: from structure to nociception
, 2022 Resumen del trabajo presentado al VIII Congreso Red Española de Canales Iónicos, celebrado en Alicante del 24 al 27 de mayo de 2022.Piezo channels constitute a unique family of ion channels that transduce mechanical forces, including membrane deformation
Taberner, Francisco J.
core
, 2022 Background: Piezo2 is a transmembrane-spanning ion channel protein implicated in multiple physiological processes, including cell proliferation and angiogenesis in many cell types.
Yangpu Jia (13196634) +4 more
core +1 more source
An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli
Advanced Science, EarlyView.An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni +6 more
wiley +1 more source
Mechanosensitive PIEZO2 channels shape coronary artery development [PDF]
Coronary arteries develop under constant mechanical stress. However, the role of mechanosensitive ion channels in this process remains poorly understood.
Sánchez-Carranza, Oscar +36 more
core +1 more source
The role of the mechanosensitive ion channel Piezo2 in the developing murine heart and brain [PDF]
, 2023 Mechanotransduction, the conversion of mechanical stimuli into electrochemical signals, is a process known to play an essential role in several physiological systems such as somatic sensation and vascular homeostasis.
Pàmpols Pérez, Mireia
core +1 more source
Neuromorphic Devices and Computing for Sensing, Memory, and Control
Advanced Science, EarlyView.This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
Piezo2 channels mediate corneal noxious mechanosensation
, 2019 Resumen del póster presentado al 49th Annual Meeting of the Society for Neuroscience, celebrado en Chicago (USA) del 19 al 23 de octubre de 2019.The transduction and encoding of mechanical forces is crucial for many of the most important physiological ...
Gomis, Ana +6 more
core +1 more source