Plants as Modulators of Melanogenesis: Role of Extracts, Pure Compounds and Patented Compositions in Therapy of Pigmentation Disorders. [PDF]
The kingdom of plants as a “green biofabric” of valuable bioactive molecules has long been used in many ailments. Currently, extracts and pure compounds of plant origin are used to aid in pigmentation skin problems by influencing the process of ...
Merecz-Sadowska A+5 more
europepmc +4 more sources
Melanin Biopolymers in Pharmacology and Medicine-Skin Pigmentation Disorders, Implications for Drug Action, Adverse Effects and Therapy. [PDF]
Melanins are biopolymeric pigments formed by a multi-step oxidation process of tyrosine in highly specialized cells called melanocytes. Melanin pigments are mainly found in the skin, iris, hair follicles, and inner ear.
Karkoszka M, Rok J, Wrześniok D.
europepmc +4 more sources
Prevention and Treatment of Skin Pigmentation Disorders. [PDF]
Pigmentation disorders are conditions that affect the color of a person's skin [...].
Khamaysi Z, Jiryis B.
europepmc +4 more sources
Shining Light on Autophagy in Skin Pigmentation and Pigmentary Disorders [PDF]
Autophagy is a vital process for cell survival and it preserves homeostasis by recycling or disassembling unnecessary or dysfunctional cellular constituents.
Daniela Kovacs+3 more
doaj +3 more sources
Identification of the Mitf gene mutation causing congenital deafness and pigmentation disorders in porcupines using BSA-Seq [PDF]
Worldwide, congenital deafness and pigmentation disorders impact millions with their diverse manifestations, and among these genetic conditions, mutations in the Microphthalmia-associated transcription factor (MITF: OMIM#156845) gene are notable for ...
Kang Li+4 more
doaj +3 more sources
Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders. [PDF]
Excessive melanin deposition in the skin leads to various skin pigmentation diseases, such as chloasma and age spots. The deposition is induced by several factors, including tyrosinase activities and ultraviolet-induced oxidative stress.
Yan C, Xing M, Zhang S, Gao Y.
europepmc +2 more sources
The etiology and molecular genetics of human pigmentation disorders. [PDF]
Baxter LL, Pavan WJ.
europepmc +4 more sources
Scar Symptoms: Pigmentation Disorders
This chapter provides an overview of the epidemiology, pathophysiology, course, measurement, and potential therapies for pigmentation disorders in scars. Pigmentation problems are a common consequence of deep partial- and full-thickness burns, other skin
Pijpe A+4 more
europepmc +2 more sources
The role of the mast cell in pigmentation disorders
The mast cell is a critical mediator of the inflammatory response by secreting histamine. While histamine is currently not regarded as a melanogen, recent studies have shown histamine release to induce melanogenesis, melanocyte proliferation and ...
Valdemar Wendelboe Nielsen+1 more
doaj +2 more sources
Skin Pigmentation Types, Causes and Treatment—A Review
Human skin pigmentation and melanin synthesis are incredibly variable, and are impacted by genetics, UV exposure, and some drugs. Patients’ physical appearance, psychological health, and social functioning are all impacted by a sizable number of skin ...
Amin Mahmood Thawabteh+4 more
doaj +2 more sources