Results 91 to 100 of about 19,713 (201)

Potassium Deficiency and Hormone Signalling in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT Potassium (K or K⁺) is a vital macronutrient that influences numerous physiological processes related to plant physiology and development. Recently, there is a growing focus on enhancing K+‐use efficiency (KUE) to ensure optimal plant growth, especially in K+ deficient soils.
Shefali Mishra, Diksha Bisht, Anna Amtmann, Ashish K. Srivastava, Girdhar K. Pandey   +4 more
wiley   +1 more source

Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.

PLoS ONE, 2015
BACKGROUND:Prostate cancer initially develops in an androgen-dependent manner but, during its progression, transitions to being androgen-independent in the advanced stage. Pin1, one of the peptidyl-prolyl cis/trans isomerases, is reportedly overexpressed
Ryuhei Kanaoka, Akifumi Kushiyama, Yasuyuki Seno, Yusuke Nakatsu, Yasuka Matsunaga, Toshiaki Fukushima, Yoshihiro Tsuchiya, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Hideaki Kamata, Akio Matsubara, Tomoichiro Asano   +12 more
doaj   +1 more source

Cyclohexyl ketone inhibitors of Pin1 dock in a trans-diaxial cyclohexane conformation. [PDF]

PLoS ONE, 2012
Cyclohexyl ketone substrate analogue inhibitors (Ac-pSer-Ψ[C = OCH]-Pip-tryptamine) of Pin1, the cell cycle regulatory peptidyl-prolyl isomerase (PPIase), were designed and synthesized as potential electrophilic acceptors for the Pin1 active site Cys113 ...
Guoyan G Xu, Carla Slebodnick, Felicia A Etzkorn   +2 more
doaj   +1 more source

Linking Superoxide Production and Scavenging in Plant Development

Plant, Cell &Environment, Volume 49, Issue 4, Page 2048-2068, April 2026.
ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák, Maryna Tsinyk, Petr Dvořák, Tomáš Takáč   +3 more
wiley   +1 more source

The PIN-FORMED (PIN) protein family of auxin transporters [PDF]

, 2009
The PIN-FORMED (PIN) proteins are secondary transporters acting in the efflux of the plant signal molecule auxin from cells. They are asymmetrically localized within cells and their polarity determines the directionality of intercellular auxin flow.
Krecek, Pavel, Skupa, Petr, Libus, Jiri, Naramoto, Satoshi, Tejos Ulloa, Ricardo, Friml, Jiri, Zazimalova, Eva   +6 more
core   +2 more sources

Natural Variations of ZmRLR1 Mediate the Root Lodging Resistance of Maize by Regulating Root Ascorbate and Auxin Homeostasis

Advanced Science, Volume 13, Issue 17, 23 March 2026.
Root lodging severely limits crop yield and quality. We reveal that ZmRLR1, a plasma membrane b‐type cytochrome, regulates lodging resistance in maize through dual roles: modulating intracellular redox balance and functioning as a novel component of clathrin‐mediated endocytosis to influence auxin homeostasis. Moreover, natural variations in the ZmRLR1
Wenshuai Lv, Pengshuai Yan, Huan Chen, Guangxian Li, Yiyue Zhao, Yanhui Chen, Wen‐Xue Li, Qingguo Du   +7 more
wiley   +1 more source

Data optimizations for constraint automata [PDF]

, 2016
Constraint automata (CA) constitute a coordination model based on finite automata on infinite words. Originally introduced for modeling of coordinators, an interesting new application of CAs is implementing coordinators (i.e., compiling CAs into ...
Arbab, Farhad, Jongmans, Sung-Shik T. Q.
core   +3 more sources

Function of PIN1 in Cancer Development and Its Inhibitors as Cancer Therapeutics

Frontiers in Cell and Developmental Biology, 2020
Peptidyl-prolyl isomerase (PIN1) specifically binds and isomerizes the phosphorylated serine/threonine–proline (pSer/Thr–Pro) motif, which results in the alteration of protein structure, function, and stability.
Ji Hoon Yu, Chun Young Im, Sang-Hyun Min
doaj   +1 more source

Development of Glioblastoma Multiforme in Patients With Human Papillomavirus‐Positive Oropharyngeal Squamous Cell Carcinoma: A Case Series

Cancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Human papillomavirus‐positive oropharyngeal squamous cell carcinoma (HPV+ OPC) patients typically exhibit reduced rates of second primary malignancies (SPMs) compared to HPV‐negative head and neck cancer patients. While HPV+ OPC patients may be predisposed to SPMs in HPV‐associated anatomical sites, the metachronous presentation of ...
Jessica T. Lovett, Michael Wotman, Ryan Denu, Aishwarya Mandava, Hardik Shah, Robert Sebra, William Westra, Marshall Posner   +7 more
wiley   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, Volume 3, Issue 1, Page 47-68, March 2026.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source