Results 121 to 130 of about 2,931 (173)
뼈 형성에서 Pin1 매개 프롤린 이성질화의 역할 [PDF]
, 2018 학위논문 (박사)-- 서울대학교 대학원 : 치의학대학원 치의과학과, 2018. 2. 류현모.One of the most reported post-translational modifications (PTMs) regulation of protein in the cell is prolin-directed phosphorylation, these phosphorylated resides also can be the targets of enzyme for ...
신혜림
core
Prolyl isomerase Pin1 et la maladie d'Alzheimer
, 2007 La maladie d'Alzheimer (MA) est une démence neurodégénérative caractérisée neuropathologiquement par une Dégénérescence Neurofibrillaire (DNF) et des dépôts amyloïdes. La DNF est constituée de protéines Tau hyper- et anormalement phosphorylées, alors que
BUEE, Luc, ANDO-ROUSSEL, Kunie
core
PIN1 overexpression enhances anchorage-independent growth in nasopharyngeal epithelial cells.
, 2016 (A) The overexpression of PIN1 was detected in NP69 cells transfected with Pin1-expressing lenti-viral vectors (Pin1 1# and Pin1 2#) by qPCR (left panel) and Western blot (middle panel).
Siu-Tim Cheung (775397) +5 more
core +1 more source
Investigating dynamic interdomain allostery in Pin1
Biophysical Reviews, 2015 Signaling proteins often sequester complementary functional sites in separate domains. How do the different domains communicate with one another? An attractive system to address this question is the mitotic regulator, human Pin1 (Lu et al. 1996). Pin-1 consists of two tethered domains: a WW domain for substrate binding, and a catalytic domain for ...
openaire +3 more sources
ABCB19/PGP19 stabilises PIN1 in membrane microdomains in Arabidopsis
, 2009 Auxin transport is mediated at the cellular level by three independent mechanisms that are characterised by the PIN-formed (PIN), P-glycoprotein (ABCB/PGP) and AUX/LAX transport proteins.
Sakai, T +41 more
core +1 more source
PIN1 in hepatocellular carcinoma is associated with TP53 gene status
, 2016 Phosphorylation of proteins on serine/threonine residues that precede proline (pSer/Thr-Pro) is specifically catalyzed by the peptidyl-prolyl cis-trans isomerase PIN1.
Bae, Jun Sang +7 more
core +1 more source
Scientific ReportsNRF2 is a transcription factor responsible for coordinating the expression of over a thousand cytoprotective genes. Although NRF2 is constitutively expressed, its stability is modulated by the redox-sensitive protein KEAP1 and other conditional binding ...
Adem Ozleyen +5 more
doaj +1 more source
, 2022 В даній роботі були проаналізовані відомі інгібітори, їх переваги і недоліки, а також синтезовано нові макроциклічні інгібітори PIN1 для майбутніх досліджень активації світлом. Ізомер, що генерується видимим світлом демонструє набагато сильнішу токсичність проти пухлинних клітин, ніж ізомер, що утворюється під ультрафіолетом.
openaire +1 more source
Putative sorting signals involved in PIN1 trafficking
, 2013 Las auxinas son hormonas vegetales involucradas en muchos procesos fisiológicos, tales como el crecimiento y diferenciación celular, la maduración de los frutos, la floración o los tropismos. Su transporte a través de la planta es polar, jugando un papel
Sancho Andrés, Gloria
core