Results 41 to 50 of about 19,713 (201)
Pathology & Oncology Research, 2013 Pin1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) plays a key role in a number of diseases including cancer and Alzheimer disease. Previous studies have identified a wide range of phosphoproteins as Pin1 substrates. Related pathways were analyzed separately.
Guo-Liang, Huang +6 more
openaire +2 more sources
Frontiers in Microbiology, 2023 IntroductionHuman parvulin peptidyl prolyl cis/trans isomerases PIN1 and PIN4 play important roles in cell cycle progression, DNA binding, protein folding and chromatin remodeling, ribosome biogenesis, and tubulin polymerization.
Umar Saeed, Zahra Zahid Piracha
doaj +1 more source
Combined in silico/in vivo analysis of mechanisms providing for root apical meristem self-organization and maintenance. [PDF]
, 2012 Background and aimsThe root apical meristem (RAM) is the plant stem cell niche which provides for the formation and continuous development of the root.
Doroshkov, AV +8 more
core +2 more sources
Frontiers in Pharmacology, 2018 Calcium/calmodulin-dependent protein kinase II (CaMKII) is abundant in the brain and functions as a mediator of calcium signaling. We found that the relative activity of CaMKII was significantly lower in the WT mouse brains than in the Pin1-/- mouse ...
Taiki Shimizu +4 more
doaj +1 more source
PIN1 gene variants in Alzheimer's disease [PDF]
BMC Medical Genetics, 2009 Abstract Background Peptidyl-prolyl isomerase, NIMA-interacting 1 (PIN1) plays a significant role in the brain and is implicated in numerous cellular processes related to Alzheimer's disease (AD) and other neurodegenerative conditions. There are confounding results concerning PIN1 activity in AD brains.
Maruszak, Aleksandra +12 more
openaire +4 more sources
Arabidopsis ROOT UVB SENSITIVE2/WEAK AUXIN RESPONSE1 is required for polar auxin transport [PDF]
, 2010 Auxin is an essential phytohormone that regulates many aspects of plant development. To identify new genes that function in auxin signaling, we performed a genetic screen for Arabidopsis thaliana mutants with an alteration in the expression of the auxin ...
Ge, L +10 more
core +2 more sources
Generalized, energy-conserving numerical simulations of particles in general relativity. II. Test particles in electromagnetic fields and GRMHD [PDF]
, 2019 Direct observations of compact objects, in the form of radiation spectra, gravitational waves from VIRGO/LIGO, and forthcoming direct imaging, are currently one of the primary source of information on the physics of plasmas in extreme astrophysical ...
Bacchini, Fabio +3 more
core +3 more sources
Phylogeny and molecular evolution analysis of PIN-FORMED 1 in angiosperm.
PLoS ONE, 2014 PIN-FORMED 1 (PIN1) is an important secondary transporter and determines the direction of intercellular auxin flow. As PIN1 performs the conserved function of auxin transport, it is expected that the sequence and structure of PIN1 is conserved. Therefore,
Pengkai Wang +8 more
doaj +1 more source
Modulation of Arabidopsis and monocot root architecture by CLAVATA3/EMBRYO SURROUNDING REGION 26 peptide [PDF]
, 2015 Plant roots are important for a wide range of processes, including nutrient and water uptake, anchoring and mechanical support, storage functions, and as the major interface with the soil environment.
Brigitte Van +7 more
core +2 more sources
Frontiers in Bioscience-Landmark, 2023 Background: The stemness characteristics of cancer cells, such as self-renewal and tumorigenicity, are considered to be responsible, in part, for tumor metastasis.
Chendan Zou +10 more
doaj +1 more source