Results 81 to 90 of about 19,713 (201)
New Phytologist, EarlyView.Summary Stomatal patterning on the plant epidermis is regulated by the ERECTA family of leucine‐rich repeat receptor kinases (LRR‐RKs). While ubiquitination has emerged as a key regulatory mechanism for the endocytosis of receptor kinases, the precise molecular connections among ERECTA ubiquitination, endocytosis, and its biological functions remain ...
Liangliang Chen +5 more
wiley +1 more source
The Effects of Cytokinin on the Transcriptional Regulation of PIN Expression in Arabidopsis thaliana [PDF]
, 2012 The processes of cell division and differentiation are critical to the development of any multicellular organism. During the formation of plant roots these processes take place at a region of the root tip called the meristem.
Burgess, Elizabeth
core +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Sugar content is a key determinant of fruit quality, and sugars also act as signalling molecules that regulate ripening processes, including anthocyanin accumulation. However, the molecular mechanisms underlying sugar accumulation and sugar signal‐mediated ripening remain incompletely understood.
Qianqian Feng +12 more
wiley +1 more source
Prolyl isomerase Pin1 regulates mouse embryonic fibroblast differentiation into adipose cells. [PDF]
PLoS ONE, 2012 A peptidyl prolyl cis/trans isomerase, Pin1, regulates insulin signal transduction. Pin1 reduces responses to insulin stimulation by binding CRTC2 (CREB-regulated transcriptional co-activator 2) and PPARγ (peroxisome prolifereator- activated receptor γ),
Takafumi Uchida +7 more
doaj +1 more source
Landscape of Pin1 in the cell cycle [PDF]
Experimental Biology and Medicine, 2015 Pin1 is a peptidyl-prolyl isomerase which plays a critical role in many diseases including cancer and Alzheimer's disease. The essential role of Pin1 is to affect stability, localization or function of phosphoproteins by catalyzing structural changes. Among the collection of Pin1 substrates, many have been shown to be involved in regulating cell cycle
Cheng-Han, Lin +6 more
openaire +2 more sources
Sweet Potato Gene Clusters Control Anthocyanin Biosynthesis and Leaf Morphology
Plant Biotechnology Journal, EarlyView.ABSTRACT Sweet potato (Ipomoea batatas) exhibits diversity in pigmentation and leaf morphology, yet the genetic architecture and regulatory organisation underlying these traits remain poorly resolved, particularly with respect to organ‐specific control.
Dong An +13 more
wiley +1 more source
Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies
Neurobiology of Disease, 2003 Pin1, a peptidyl-prolyl isomerase binds to mitotic serine or threonine phosphoproteins. In Alzheimer's disease (AD) evidence points to the reactivation of mitosis in vulnerable neurons.
Pankajavalli Ramakrishnan +2 more
doaj +1 more source
Dynamic regulation of Pin1 expression and function during zebrafish development. [PDF]
PLoS ONE, 2017 The prolyl isomerase Pin1 plays a key role in the modulation of proline-directed phosphorylation signaling by inducing local conformational changes in phosphorylated protein substrates.
Maria Solange Ibarra +7 more
doaj +1 more source
Pin1 regulates parathyroid hormone mRNA stability [PDF]
Journal of Clinical Investigation, 2009 Secondary hyperparathyroidism often occurs in chronic kidney disease (CKD) and vitamin D deficiency, resulting in increased fractures and mortality. Understanding factors that stimulate parathyroid hormone (PTH) synthesis is important for devising methods to treat this condition.
openaire +2 more sources
Pin1‐Targeted Therapy for Systemic Lupus Erythematosus [PDF]
Arthritis & Rheumatology, 2016 ObjectiveSystemic lupus erythematosus (SLE) is a debilitating autoimmune disease affecting multiple organs in the body, but therapeutic options are still very limited and often come with adverse effects. Increasing evidence has underlined an important role of the Toll‐like receptor 7 (TLR‐7)/TLR‐9/interleukin‐1 receptor–associated kinase 1 (IRAK‐1 ...
Shuo, Wei +8 more
openaire +2 more sources