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Cellular Basis of Pineal Gland Development: Emerging Role of Microglia as Phenotype Regulator. [PDF]
PLoS ONE, 2016 The adult pineal gland is composed of pinealocytes, astrocytes, microglia, and other interstitial cells that have been described in detail. However, factors that contribute to pineal development have not been fully elucidated, nor have pineal cell ...
María P Ibañez Rodriguez +2 more
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Pineal Gland Tumors: A Review. [PDF]
Cancers (Basel), 2021 The pineal gland is a small, pinecone-shaped endocrine gland that participates in the biological rhythm regulation of vertebrates. The recognized major product of the pineal gland is melatonin—a multifunctional endogenous indoleamine. Accumulating evidence suggests that the pineal gland is important for preserving ideal health conditions in vertebrate.
Favero G, Bonomini F, Rezzani R.
europepmc +6 more sources
Comparison of Three Methods for the Estimation of Pineal Gland Volume Using Magnetic Resonance Imaging [PDF]
The Scientific World Journal, 2012 Pineal gland is a very important neuroendocrine organ with many physiological functions such as regulating circadian rhythm. Radiologically, the pineal gland volume is clinically important because it is usually difficult to distinguish small pineal ...
Niyazi Acer +5 more
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Pineal Gland from the Cell Culture to Animal Models: A Review [PDF]
Life, 2022 This review demonstrates current literature on pineal gland physiology, pathology, and animal model experiments to concisely explore future needs in research development with respect to pineal gland function and neuro-regenerative properties.
Alekhya Peruri +14 more
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Molecular Neurodegeneration, 2019 Alzheimer’s disease (AD) is a globally common neurodegenerative disease, which is accompanied by alterations to various lifestyle patterns, such as sleep disturbance.
Juhyun Song
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Serotonin modulates melatonin synthesis as an autocrine neurotransmitter in the pineal gland. [PDF]
Proc Natl Acad Sci U S A, 2021 Significance The pineal gland secretes melatonin at night mainly driven by adrenergic sympathetic inputs. Many other neurotransmitters are found in the pineal gland, suggesting potential fine modulation of melatonin release.
Lee BH, Hille B, Koh DS.
europepmc +2 more sources
Prevalence of pineal gland calcification: systematic review and meta-analysis [PDF]
Systematic Reviews, 2023 Background Pineal gland calcification is the formation of corpora arenacea predominantly composed of calcium and phosphorus. It plays an important role in regulating the light/dark circadian changes to synchronize their daily physiological activities ...
Daniel Gashaneh Belay +1 more
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Molecules, 2018 The pineal gland is a unique organ that synthesizes melatonin as the signaling molecule of natural photoperiodic environment and as a potent neuronal protective antioxidant.
Dun Xian Tan +3 more
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Effects of different light intensities on the transcriptome changes of duck retina and pineal gland [PDF]
Poultry Science, 2022 : The light intensity can affect the production performance of animals. The retina and pineal gland, closely linked, are directly photosensitive organs.
Jingjing Qi +12 more
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Pineal gland volume loss in females with multiple sclerosis [PDF]
Frontiers in NeuroanatomyIntroductionMultiple sclerosis has a complex pathophysiology, and numerous risk factors can contribute to its development, like exposure to sunlight that is associated with serum levels of melatonin.
Miloš Vuković +7 more
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