Results 1 to 10 of about 508,086 (240)

Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression

PLoS ONE, 2018
The vertebrate pineal gland is dedicated to the production of the hormone melatonin, which increases at night to influence circadian and seasonal rhythms. This increase is associated with dramatic changes in the pineal transcriptome.
Joseph C. Mays, Michael C. Kelly, S. Coon, L. Holtzclaw, M. F. Rath, M. Kelley, D. Klein   +6 more
semanticscholar   +1 more source

Profiling Temporal Changes of the Pineal Transcriptomes at Single Cell Level Upon Neonatal HIBD

Frontiers in Cell and Developmental Biology, 2022
Neonatal hypoxic-ischemic brain damage (HIBD) often results in various neurological deficits. Among them, a common, yet often neglected, symptom is circadian rhythm disorders. Previous studies revealed that the occurrence of cysts in the pineal gland, an
Xin Ding, Tao Pan, Qiuyan Tian, Wenxi Huang, Lauren S Hayashi, Qin Liu, Fuyong Li, Li-Xiao Xu, Po Miao, Xiaofeng Yang, Bin Sun, Chen-Xi Feng, Xing Feng, Mei Li, Jian Huang   +14 more
doaj   +1 more source

Macro-microscopical aspects of the buffalo (Bubalus bubalis Linnaeus, 1758) pineal gland [PDF]

Biotemas, 2009
Gross and microscopical aspects of the buffalo pineal gland were described in seasonal parturition animals, since this gland is responsible for melatonin secretion which acts upon the hypothalamus-hypophysis reproductive axis feedback system.
Ana Flávia de Carvalho, Carlos Eduardo Ambrósio, Maria Angélica Miglino, Celina Almeida Furlanetto Mançanares, Francisco Javier Hernandez Blazquez   +4 more
doaj   +2 more sources

Pineal Gland Volume in Major Depressive and Bipolar Disorders

Frontiers in Psychiatry, 2020
Abnormal melatonin secretion has been demonstrated in patients with affective disorders such as major depressive disorder (MDD) and bipolar disorder (BD).
Tsutomu Takahashi, Daiki Sasabayashi, Murat Yücel, Sarah Whittle, Valentina Lorenzetti, Mark Walterfang, Mark Walterfang, Mark Walterfang, Michio Suzuki, Christos Pantelis, Gin S. Malhi, Gin S. Malhi, Nicholas B. Allen   +12 more
doaj   +1 more source

Morphofunctional and signaling molecules overlap of the pineal gland and thymus: role and significance in aging

OncoTarget, 2016
Deficits in neuroendocrine-immune system functioning, including alterations in pineal and thymic glands, contribute to aging-associated diseases. This study looks at ageing-associated alterations in pineal and thymic gland functioning evaluating common ...
M. Paltsev, V. Polyakova, I. Kvetnoy, George Anderson, T. Kvetnaia, N. Linkova, E. Paltseva, R. Rubino, S. De Cosmo, A. De Cata, G. Mazzoccoli   +10 more
semanticscholar   +1 more source

HISTOMORPHOGENESIS OF PINEAL GLAND IN GOAT FOETUSES [PDF]

Journal of Veterinary and Animal Sciences, 2011
Prenatal development of pineal gland in goat was studied using 52 goat foetuses ranging from 1.4cm CRL (24 days of gestation) to 41.5cm CRL (full term). Pineal gland developed during the seventh week as a conical evagination on the caudo-dorsal aspect of
K. M. Lucy, K. R. Harshan, J. J. Chungath, N. Ashok   +3 more
doaj  

MRI-based assessment of the pineal gland in a large population of children aged 0–5 years and comparison with pineoblastoma: part I, the solid gland

Neuroradiology, 2016
IntroductionDifferentiation between normal solid (non-cystic) pineal glands and pineal pathologies on brain MRI is difficult. The aim of this study was to assess the size of the solid pineal gland in children (0–5 years) and compare the findings with ...
P. Galluzzi, M. D. de Jong, S. Sirin, P. Maeder, P. Piu, A. Cerase, L. Monti, H. Brisse, J. Castelijns, P. de Graaf, S. Goericke   +10 more
semanticscholar   +1 more source

Evaluation of prevalence and dimension of Pineal Gland Calcification by cone-beam computed tomography (CBCT)

Cumhuriyet Dental Journal, 2022
Objective: This study aimed to investigate the prevalence and dimensions of pineal gland calcification using cone-beam computed tomography (CBCT) in patients undergoing dental treatment. Materials and Methods: CBCTs that localized pineal gland in the fov
Emrah Dilaver, Sina Uçkan, Muazzez Suzen   +2 more
doaj   +1 more source

Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia

Brain Research Bulletin
Using a chronic unpredictable mild stress (CUMS) combined with multi-platform water environment sleep deprivation (SD) as an animal model, the occurrence and development of human depression combined with insomnia were simulated.
Zirong Li, Yi Shu, Deguo Liu, Sheng Xie, Liangbo Xian, Jiaqi Luo, Xiuwen Huang, Haixing Jiang   +7 more
doaj   +1 more source

The light-induced transcriptome of the zebrafish pineal gland reveals complex regulation of the circadian clockwork by light

Nucleic Acids Research, 2014
Light constitutes a primary signal whereby endogenous circadian clocks are synchronized (‘entrained’) with the day/night cycle. The molecular mechanisms underlying this vital process are known to require gene activation, yet are incompletely understood ...
Z. Ben-Moshe, Shahar Alon, P. Mracek, Lior Faigenbloom, Adi Tovin, G. Vatine, E. Eisenberg, N. Foulkes, Y. Gothilf   +8 more
semanticscholar   +1 more source