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Pineal Gland Tumors: A Review. [PDF]

open access: yesCancers (Basel), 2021
The pineal gland is a small, pinecone-shaped endocrine gland that participates in the biological rhythm regulation of vertebrates. The recognized major product of the pineal gland is melatonin—a multifunctional endogenous indoleamine. Accumulating evidence suggests that the pineal gland is important for preserving ideal health conditions in vertebrate.
Favero G, Bonomini F, Rezzani R.
europepmc   +6 more sources

Pineal Gland from the Cell Culture to Animal Models: A Review [PDF]

open access: yesLife, 2022
This review demonstrates current literature on pineal gland physiology, pathology, and animal model experiments to concisely explore future needs in research development with respect to pineal gland function and neuro-regenerative properties.
Alekhya Peruri   +14 more
doaj   +2 more sources

Prevalence of pineal gland calcification: systematic review and meta-analysis [PDF]

open access: yesSystematic Reviews, 2023
Background Pineal gland calcification is the formation of corpora arenacea predominantly composed of calcium and phosphorus. It plays an important role in regulating the light/dark circadian changes to synchronize their daily physiological activities ...
Daniel Gashaneh Belay   +1 more
doaj   +2 more sources

Effects of different light intensities on the transcriptome changes of duck retina and pineal gland [PDF]

open access: yesPoultry Science, 2022
: The light intensity can affect the production performance of animals. The retina and pineal gland, closely linked, are directly photosensitive organs.
Jingjing Qi   +12 more
doaj   +2 more sources

Utility of 18F-FDG PET/CT in Detecting Spinal Drop Metastases from Pineal Gland Tumors [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology
Pineal gland tumors are significant despite being rare (
Kabilash Dhayalan   +3 more
doaj   +2 more sources

Pineal gland volume loss in females with multiple sclerosis [PDF]

open access: yesFrontiers in Neuroanatomy
IntroductionMultiple sclerosis has a complex pathophysiology, and numerous risk factors can contribute to its development, like exposure to sunlight that is associated with serum levels of melatonin.
Miloš Vuković   +7 more
doaj   +2 more sources

AAV vectors accumulate in the pineal gland after injections into the brain or spinal cord [PDF]

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
AAV vectors are being used extensively for gene-modifying therapies for neurological disorders. Here, we report the surprising discovery that injections of different AAVs into the brain, spinal cord, or cerebrospinal fluid (CSF) lead to robust ...
Oswald Steward   +4 more
doaj   +2 more sources

Morphology of the Human Pineal Gland Studied by Freeze-Fracturing in Scanning Electron Microscopy [PDF]

open access: yesLife
The human pineal gland is the largest producer of the hormone melatonin. Pineal acervuli (brain sand), calcified concretions in the pineal gland, have long been studied because of their association with ageing, melatonin production, and neurological ...
Simona Polakovičová   +3 more
doaj   +2 more sources

The antisteroid action of the pineal gland [PDF]

open access: bronzeAnnales de Biologie Animale Biochimie Biophysique, 1979
The study presents the data gathered along the years on the antisteroid action of the pineal gland. Thus, it was demonstrated that administration of pineal polypeptides to the rabbit lowers the urinary 17-KS both of testicular and adrenal origin. Conversely, pinealectomy caused an increase in the level of these steroid hormones.
E Damian
openalex   +5 more sources

Retinoic Acid Signalling in the Pineal Gland Is Conserved across Mammalian Species and Its Transcriptional Activity Is Inhibited by Melatonin [PDF]

open access: yesCells, 2023
The pineal gland is integral to the circadian timing system due to its role in nightly melatonin production. Retinoic acid (RA) is a potent regulator of gene transcription and has previously been found to exhibit diurnal changes in synthesis and ...
Anna Ashton   +5 more
doaj   +2 more sources

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