Results 101 to 110 of about 44,238 (268)

Emerging Perspectives on Gonadotropin Regulation in Vertebrates Revealed by the Discovery of FSH‐RH in Teleosts

open access: yesBioEssays, Volume 47, Issue 11, November 2025.
Regarding pituitary gonadotropin regulation, recent studies have shown that in mammals, FSH and LH are regulated by a single GnRH (solo GnRH model), whereas in teleosts, they are regulated by CCK (FSH‐RH) and GnRH (LH‐RH), respectively (dual GnRH model).
Daichi Kayo   +3 more
wiley   +1 more source

Peculiarities of psammoma bodies distribution in the human pineal gland: a new approach to determining the functional significance of pineal gland calcifications

open access: yesСибирский научный медицинский журнал
The pineal gland is a neuroendocrine gland that synchronizes the functional activity of body organs with the light regime using the hormone melatonin, which is actively released into the bloodstream at night. Melatonin is synthesized by pinealocytes, the
D. A. Sufieva   +3 more
doaj   +1 more source

The reno-pineal axis: A novel role for melatonin

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
The pineal gland is a tiny endocrine gland whose physiologic role has been the focus of much research and much more speculation over the past century.
Sanjay Kalra   +2 more
doaj   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

In silico genome wide mining of conserved and novel miRNAs in the brain and pineal gland of Danio rerio using small RNA sequencing data

open access: yesGenomics Data, 2016
MicroRNAs (miRNAs) are small, non-coding RNA molecules that bind to the mRNA of the target genes and regulate the expression of the gene at the post-transcriptional level. Zebrafish is an economically important freshwater fish species globally considered
Suyash Agarwal   +6 more
doaj   +1 more source

EVOLUTION OF THE CIRCADIAN CLOCK IN EXTREME ENVIRONMENT: LESSONS FROM CAVEFISH. [PDF]

open access: yes, 2010
Evolution has been strongly influenced by the daily cycles of temperature and light imposed by the rotation of the Earth. Fascinating demonstrations of this are seen in extreme environments such as caves where some animals have remained completely ...
Cavallari, Nicola
core  

Expression and cellular localization of the transcription factor NeuroD1 in the developing and adult rat pineal gland [PDF]

open access: yes, 2015
Circadian rhythms govern many aspects of mammalian physiology. The daily pattern of melatonin synthesis and secretion is one of the classic examples of circadian oscillations.
Benitez, Sergio G.   +5 more
core   +2 more sources

Melatonin Activates AMPK Pathway to Regulate the Regeneration of Slow Muscle Fibers in Skeletal Muscle Injury Repair

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
The figure illustrates in vitro (melatonin‐treated C2C12 myoblasts) and in vivo (mouse frostbite‐induced tibialis anterior muscle injury with melatonin administration) models. Melatonin activates AMPK, which phosphorylates PGC‐1α to enhance mitochondrial bioenergetics (decreased ROS and LDH, increased ATP, mtDNA, membrane potential, and oxygen ...
Wei Xie   +8 more
wiley   +1 more source

Scientific Research on the Pineal Gland: A Bibliometric Analysis from Its First Publication

open access: yesEndocrinology Research and Practice
Objective: The bibliometric perspective examines publications using a quantitative way and statistics to analyze them. The purpose of the current study was to perform a comprehensive overview of the research on the pineal gland through bibliometric ...
Esra Şen   +2 more
doaj   +1 more source

Emil du Bois-Reymond on "The Seat of the Soul" [PDF]

open access: yes, 2014
The German pioneer of electrophysiology, Emil du Bois-Reymond (1818–1896), is generally assumed to have remained silent on the subject of the brain. However, the archive of his papers in Berlin contains manuscript notes to a lecture on “The Seat of the ...
Finkelstein, Gabriel
core   +1 more source

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