Results 11 to 20 of about 1,287 (164)

Insulin-like effect of pinitol [PDF]

British Journal of Pharmacology, 2000
D‐pinitol (3‐O‐methyl‐chiroinositol), an active principle of the traditional antidiabetic plant Bougainvillea spectabilis, is claimed to exert insulin‐like effects. This study investigates the effect of D‐pinitol on glucose homeostasis in animal models of diabetes, and on glucose transport by cultured muscle cells.
Clifford J Bailey
exaly   +3 more sources

Isolation and Quantification of Pinitol, a Bioactive Cyclitol, in spp [PDF]

Natural Product Communications, 2016
The genus Retama (Fabaceae) is widely distributed in the Mediterranean region. In the present study, pinitol (3- O -methyl- chiro -inositol), an anti-inflammatory and antidiabetic molecule, was isolated from aerial parts of R.
Nuria H. González-Mauraza, Antonio J. León-González, José L. Espartero, Juan B. Gallego-Fernández, Marina Sánchez-Hidalgo, Carmen Martin-Cordero   +5 more
doaj   +5 more sources

Neuroprotective Effect of D-Pinitol Against MPTP-Induced Parkinsonism in C57BL/6J Mice [PDF]

Antioxidants
Parkinson’s disease is the second most common neurodegenerative disease in the world. Natural products can offer a possible option of neuroprotective agents for preventing neurodegenerative diseases.
María del Carmen Juárez-Vázquez, María Leonor González-Rivera, Ramsés Maximiliano Ramírez-Martínez, Athzirys Alejandra Melecio-Hernández, Juan C. Jiménez-Cruz, Gabriela Josefina López-González, Juan Carlos Barragán-Gálvez, Juan Ramón Zapata-Morales, Judit A. Aviña-Verduzco, Angel Josabad Alonso-Castro   +9 more
doaj   +2 more sources

NMR Identification and Quantification of Galactinol in Green Coffea arabica: Implications for Traceability and Adulteration. [PDF]

J Food Sci
ABSTRACT Among coffee low‐molecular‐weight carbohydrates, galactinol plays an important role in coffee physiology and quality, having received attention also for its potential use as a marker of geographical origin. Nevertheless, data on the occurrence of this sugar in green coffee beans remain limited.
De Angelis E, Fabbian S, Schievano E, Guercia E, Fornasari A, Piva E, Pozzebon M, Navarini L.   +7 more
europepmc   +2 more sources

Pinitol Improves Lipopolysaccharide-Induced Cellular Damage in Human Dermal Microvascular Endothelial Cells [PDF]

Molecules
3-O-Methyl-D-chiro-inositol (pinitol) has been reported to possess insulin-like effects and is known as one of the anti-diabetic agents for improving muscle and liver function.
Min Young Go, Jinsick Kim, Chae Young Jeon, Mujun Kim, Dong Wook Shin   +4 more
doaj   +2 more sources

Neuropharmacological and Antipyretic Potentials of Streblus asper Leaves: Integrated In Vivo and In Silico Approaches. [PDF]

ScientificWorldJournal
Streblus asper (Moraceae) is traditionally used for neurological and febrile disorders, but its pharmacological basis remains unclear. This study evaluated the S. asper leaf methanolic extract (SAL‐ME) for anxiolytic, antidepressant, sedative, and antipyretic activities using Swiss albino mice and in silico docking analyses.
Rasel MH, Mamun MJI, Sumi SS, Hasan MN, Rahman M, Uddin SMN.   +5 more
europepmc   +2 more sources

Pinitol Improves Diabetic Foot Ulcers in Streptozotocin-Induced Diabetes Rats Through Upregulation of Nrf2/HO-1 Signaling [PDF]

Antioxidants
Diabetic foot ulcers represent a severe complication of diabetes, often resulting in amputation and high mortality rates. Currently, there are no treatments for diabetic foot ulcers other than antibiotics and dressings.
Jinsick Kim, Min Young Go, Chae Young Jeon, Jung Un Shin, Mujun Kim, Hye Won Lim, Dong Wook Shin   +6 more
doaj   +2 more sources

Anti-inflammatory activity of d-pinitol possibly through inhibiting COX-2 enzyme: in vivo and in silico studies [PDF]

Frontiers in Chemistry
Introduction: D-pinitol, a naturally occurring inositol, has diverse biological activities like antioxidant, antimicrobial and anticancer activities. This study aimed to evaluate anti-inflammatory effect of d-pinitol in a chick model.
Mst. Farjanamul Haque, Heba A. S. El-Nashar, Md. Showkoth Akbor, Mohammed Alfaifi, Mehedi Hasan Bappi, Afsana Kabir Chowdhury, Muhammad Kamal Hossain, Muhammad Kamal Hossain, Mohamed El-Shazly, Tala Albayouk, Na’il Saleh, Muhammad Torequl Islam, Muhammad Torequl Islam, Muhammad Torequl Islam   +13 more
doaj   +2 more sources

Isolation and quantification of pinitol in Argyrolobium roseum plant, by 1H-NMR

Journal of Saudi Chemical Society, 2016
Chemical investigations on ethanolic extract of Argyrolobium roseum led to the isolation of Pinitol as the major constituent of the plant. Pinitol is chemically known as 3-O-methyl-D-Chiro-inositol and has been found to possess anti-diabetic activity. It
Neha Sharma, M K Verma, Naresh K Satti
exaly   +3 more sources

Effects of High Hydrostatic Pressure on the Distribution of Oligosaccharides, Pinitol, Soysapapogenol A, and Fatty Acids in Soybean [PDF]

Foods
The effects of high hydrostatic pressure (HHP) treatment (100–600 MPa for 10–60 min) and thermal treatment (boiling for 10–60 min) on oligosaccharides, pinitol, and soyasapogenol A as taste ingredients in soybean (Glycine max (L.) Merr.) (cv. Yukihomare)
Shigeaki Ueno, Hsiuming Liu, Risa Kishino, Yuka Oshikiri, Yuki Kawaguchi, Akio Watanabe, Wataru Kobayashi, Reiko Shimada   +7 more
doaj   +2 more sources