Results 31 to 40 of about 1,287 (164)

D-Pinitol Improved Glucose Metabolism and Inhibited Bone Loss in Mice with Diabetic Osteoporosis

Molecules, 2023
Diabetic osteoporosis (DO) has been increasingly recognized as an important complication of diabetes. D-pinitol, a natural compound found in various legumes, is known for its anti-diabetic function, but its effect on DO has not been investigated.
Xinxin Liu, Tomoyuki Koyama
doaj   +1 more source

D-Pinitol Increases Insulin Secretion and Regulates Hepatic Lipid Metabolism in Msg-Obese Mice [PDF]

Anais da Academia Brasileira de Ciências, 2020
D-pinitol is one of the major inositol found in plants and studies suggest its potential hypoglycemic and hypolipidemic actions in diabetic rodents. Here, we investigated the actions of D-pinitol on adiposity, and in lipid and glycemic homeostasis in ...
JOEL A. DA SILVA JÚNIOR, AMANDA C.V.F. DA SILVA, LETÍCIA S. FIGUEIREDO, THIAGO R. ARAUJO, ISRAELLE N. FREITAS, EVERARDO M. CARNEIRO, ELANE S. RIBEIRO, ROSANE A. RIBEIRO   +7 more
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Effects of d-pinitol on diabetes mellitus: an updated review

Bulletin of the National Research Centre, 2022
Background The awareness in the consumption of plant-based food has gained attention in the recent years. Phytochemicals are thought to play a critical role in health promotion and in the prevention and management of chronic diseases.
Anandakumar Pandi, Vanitha Manickam Kalappan, Naveenkumar Chandrashekar   +2 more
doaj   +1 more source

initol protects against endoplasmic reticulum stress and apoptosis in hepatic ischemia-reperfusion injury via modulation of AFT4-CHOP/GRP78 and caspase-3 signaling pathways

International Journal of Immunopathology and Pharmacology, 2021
Hepatic ischemia-reperfusion injury (IRI) is a major unavoidable clinical problem often accompanying various liver surgery and transplantation. d-P initol, a cyclic polyol, exhibits hepatoprotective efficacy.
Lei Yan, Heng Luo, Xingsheng Li, Yongyong Li   +3 more
doaj   +1 more source

Exogenously Applied Cyclitols and Biosynthesized Silver Nanoparticles Affect the Soluble Carbohydrate Profiles of Wheat (Triticum aestivum L.) Seedling

Plants, 2023
Cyclitols, such as myo-inositol and its isomers and methyl derivatives (i.e., d-chiro-inositol and d-pinitol (3-O-methyl-chiro-inositol)), are classified as osmolytes and osmoprotectants and are significantly involved in plant responses to abiotic ...
Lesław B. Lahuta, Joanna Szablińska-Piernik, Karolina Stałanowska, Marcin Horbowicz, Ryszard J. Górecki, Viorica Railean, Paweł Pomastowski, Bogusław Buszewski   +7 more
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Anti-Alzheimer Potential of a New (+)-Pinitol Glycoside Isolated from Tamarindus indica Pulp: In Vivo and In Silico Evaluations

Metabolites, 2023
Tamarindus indica Linn (tamarind, F. Leguminosae) is one of the most widely consumed edible fruits in the world. Phytochemical investigation of tamarind pulp n-butanol fraction yielded one new (+)-pinitol glycoside compound 1 (25% w/w), and 1D, 2D NMR ...
Esraa M. Mohamed, Abeer H. Elmaidomy, Rania Alaaeldin, Faisal Alsenani, Faisal H. Altemani, Naseh A. Algehainy, Mohammad A Alanazi, Alaa Bagalagel, Abdulhamid Althagafi, Mahmoud A Elrehany, Usama Ramadan Abdelmohsen   +10 more
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D-Pinitol Content and Antioxidant and Antidiabetic Activities of Five Bougainvillea spectabilis Willd. Cultivars

Pharmaceuticals, 2023
Diabetes mellitus is a major challenge for global health, and Bougainvillea spectabilis Willd. (B. spectabilis) is a widely used herbal remedy with diverse cultivars traditionally used for diabetes treatment.
Fatma Abo-Elghiet, Amal H. Ahmed, Hanan F. Aly, Eman A. Younis, Mohamed A. Rabeh, Saad Ali Alshehri, Khalid S. A. Alshahrani, Shaza A. Mohamed   +7 more
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NMR-Based Metabolomics Reveals Effects of Water Stress in the Primary and Specialized Metabolisms of Bauhinia ungulata L. (Fabaceae)

Metabolites, 2023
Bauhinia ungulata is a plant used in Brazilian traditional medicine for the treatment of diabetes. Phytochemical studies revealed flavonoids and the saccharide pinitol related to hypoglycemic activity of the Bauhinia species.
Ana Júlia Borim de Souza, Fernanda Maria Marins Ocampos, Rafael Catoia Pulgrossi, Anne Lígia Dokkedal, Luiz Alberto Colnago, Inês Cechin, Luiz Leonardo Saldanha   +6 more
doaj   +1 more source

Activation of eNOS by D-pinitol Induces an Endothelium-Dependent Vasodilatation in Mouse Mesenteric Artery

Frontiers in Pharmacology, 2018
D-pinitol is a cyclitol present in several edible plant species and extensively investigated for the treatment of metabolic diseases in humans, as food supplement, and demonstrated protective effects in the cardiovascular system.
Luciana N. Moreira, Josiane F. Silva, Grazielle C. Silva, Virgínia S. Lemos, Steyner F. Cortes   +4 more
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Inhibitory activity of traditional plants against Mycobacterium smegmatis and their action on Filamenting temperature sensitive mutant Z (FtsZ)-A cell division protein.

PLoS ONE, 2020
The study was designed to assess whether plant extracts / phytochemical (D-Pinitol) synergistically combine with antituberculosis drugs and act on Mycobacterium smegmatis (M. smegmatis) as well as assess their mode of action on Mycobacterium tuberculosis
Radhika Ravindran, Gayathri Chakrapani, Kartik Mitra, Mukesh Doble   +3 more
doaj   +1 more source