Results 161 to 170 of about 37,375 (191)

Correction: Mitochondrial quality control in diabetes mellitus and complications: molecular mechanisms and therapeutic strategies. [PDF]

Cell Death Dis
Chen Y, Liu X, Liu Y, Li Y, Li D, Mei Z, Deng Y.   +6 more
europepmc   +1 more source

Regulation of UBC12 expression and protein neddylation by PINK1 suggests a primate-specific function. [PDF]

Zool Res
Huang W, Xu T, Zhou GK, Li YX, Lin CZ, Chen XS, Zhang T, Jiang L, Liu YT, Xiong X, Liang XY, Guo XY, Li SH, Li XJ, Yang WL.   +14 more
europepmc   +1 more source

Mitophagy in gastrointestinal tumors: mechanisms and new targets for immunotherapy. [PDF]

Front Oncol
Zhang T, Ren Z, Tang B, Man R, Wang L, Wang Q, Peng J, Yu Y.   +7 more
europepmc   +1 more source

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FUNDC1 collaborates with PINK1 in regulating mitochondrial Fission and compensating for PINK1 deficiency

Biochemical and Biophysical Research Communications, 2023
Parkinson's disease is presently thought to have its molecular roots in the alteration of PINK1-mediated mitophagy and mitochondrial dynamics. Finding new suppressors of the pathway is essential for developing cutting-edge treatment approaches. Our study shows that FUNDC1 suppressed PINK1 mutant phenotypes in Drosophila.
Jing, Xu, Zhouyang, Deng, Shuai, Shang, Caifang, Wang, Hailong, Han   +4 more
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PINK1: The guard of mitochondria

Life Sciences, 2020
PTEN-induced putative kinase 1 (PINK1) performs many important functions in cells and has been highlighted for its role in early-onset Parkinson's disease. In recent years, an increasing number of studies have revealed the involvement of PINK1 in regulation of a variety of cell physiological and pathophysiological processes, of which regulation of ...
Nan, Wang, Peining, Zhu, Renxuan, Huang, Chong, Wang, Liankun, Sun, Beiwu, Lan, Yichun, He, Hongyang, Zhao, Yufei, Gao   +8 more
openaire   +2 more sources

Hsp70 participates in PINK1-mediated mitophagy by regulating the stability of PINK1

Neuroscience Letters, 2018
Loss-of function mutations in PTEN-induced putative kinase 1 (PINK1) is one of the most common causes of autosomal recessive Parkinson's disease (PD). PINK1-mediated mitophagy is critical to mitochondrial quality control and plays an important role in PD pathogenesis.
Qian, Zheng, Chuxin, Huang, Jifeng, Guo, Jieqiong, Tan, Chunyu, Wang, Beisha, Tang, Hainan, Zhang   +6 more
openaire   +2 more sources