Results 71 to 80 of about 23,205 (164)

Attenuated PINK1 autophosphorylation play neuroprotective and anti-seizure roles in neonatal hypoxia

Scientific Reports
This study investigated the roles and mechanisms of PINK1 activity in neonatal hypoxia-induced seizures with shRNA intervention targeting translocase outer mitochondrial membrane 7 (TOM7), the positive regulator of PINK1 autophosphorylation, or ...
Yi Yuan, Xiaoqian Wang, Yaru Cui, Hua Zhou, Wenna Li, Qian Teng, Hongjin Wang, Bohan Sun, Qiaoyun Wang, Hongliu Sun, Jianhua Tang   +10 more
doaj   +1 more source

Evaluation of PINK1 protein expression as a predictive marker for the efficacy of adjuvant chemotherapy in colorectal cancer: a retrospective study

BMC Gastroenterology
Background PTEN-induced kinase 1 (PINK1) is involved in mitochondrial quality control via mitophagy, and recent studies have reported that its overexpression is associated with chemoresistance and poor prognosis in multiple malignant tumors. However, the
Takatsugu Fujii, Masataka Hirasaki, Yasuo Kamakura, Tomonori Kawasaki, Satoshi Yamasaki, Yasuhiro Ishiyama, Chikashi Hiranuma, Tetsuya Hamaguchi, Yasumitsu Hirano, Shinichi Sakuramoto   +9 more
doaj   +1 more source

Tickled PINK1 [PDF]

Nature Chemical Biology, 2013
openaire   +1 more source

Glucose concentration of neuronal media formulations influences PINK1-dependent mitophagy in human iNeurons. [PDF]

Autophagy Rep
O'Callaghan B, Melandri D, Soltic D, Cosker K, Soutar MPM, Evans JR, Lucas-Clarke H, Robin J, Gandhi S, Birsa N, Arber C, Wray S, Plun-Favreau H.   +12 more
europepmc   +1 more source

Promoting mitochondrial dynamics by inhibiting the PINK1–PRKN pathway to relieve diabetic nephropathy

Disease Models & Mechanisms
Jun-yi Zhu, Joyce van de Leemput, Zhe Han   +2 more
doaj   +1 more source

UBC/UBA52 silencing restores PINK1-Parkin-mediated mitochondrial autophagy in allergic rhinitis. [PDF]

PLoS One
Lu Q, Yang Y, Ruan B.
europepmc   +1 more source

Osteocytic Pink1/Prkn modulates M6P metabolism and contributes to GC-induced bone loss. [PDF]

J Orthop Translat
Mei J, Zheng Z, Liu D, Zhou J, Gao C, Ma Y, Ding P, Gao J, Huang Y, Yin J.   +9 more
europepmc   +1 more source

Disruption of a GalR2-mitochondrial axis in the ventral hippocampus contributes to depression-like phenotypes after prenatal stress. [PDF]

Front Psychiatry
Yue J, Zhang J, Yu X, Li Z, Wang Y, Zhao S, Bai Y, Li X, Li H, Yang Y, Xu ZD.   +10 more
europepmc   +1 more source

The role of phospho-ubiquitin in mitochondrial health and diseases. [PDF]

J Biol Chem
Suresh K, Rainville C, Sterner DE, Goldberg MS, Butt TR.   +4 more
europepmc   +1 more source

Mitophagy in cisplatin-induced kidney injury: regulatory mechanisms and therapeutic targets. [PDF]

Ann Med
Yuan C, Jiang J, Ji J, Ni L.
europepmc   +1 more source