Results 111 to 120 of about 40,506 (345)
Plant enzyme reactions leading to the formation of heterocyclic compounds. 1. The formation of unsaturated pyrrolidine and piperidine compounds [PDF]
, 1955 P. J. Mann, W. R. Smithies
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Research progress of donepezil for treating mild to moderate Alzheimer's disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2017 Donepezil is the second generation of cholinesterase inhibitors (ChEIs), which has a good effect on mild to moderate Alzheimer's disease (AD). In recent years, there were a lot of studies on the mechanism of donepezil. This paper mainly introduces the
Xin-xin LI, Yun-yun ZHANG, Bin WANG
doaj
Angewandte Chemie International Edition, EarlyView.We present a metal‐free method for aromatic deuterium labeling via photoexcitation in deuterated HFIP. This approach leverages the enhanced basicity of excited‐state aromatics to achieve selective hydrogen isotope exchange at challenging positions. Demonstrated on complex drug molecules, this efficient strategy provides a valuable tool for isotope ...
Eva Rivera‐Chao +5 more
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Angewandte Chemie International Edition, Accepted Article.This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
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5-Hydroxy-Piperidine-2-Carboxylic Acid in Green Plants. [PDF]
, 1954 Artturi I. Virtanen +3 more
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Nickel‐Catalyzed Suzuki‐Miyaura Cross‐Coupling Reaction of Aliphatic Alcohol Derivatives
Angewandte Chemie International Edition, Accepted Article.Reactions leveraging readily available starting materials are valuable for synthetic utility, especially for late‐stage functionalization. Herein, we report a nickel‐catalyzed Suzuki‐Miyaura cross‐coupling reaction of aliphatic sulfonates with aryl boronic acids.
Elizabeth R Jarvo +3 more
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Journal of Applied Polymer Science, EarlyView.ABSTRACT The aim of the research was to find a fast and reliable measurement method for the prediction of functional properties such as compression set (CS) of rubber profiles. Research shows that the best method for testing network density and crosslinks structure for a finished product, such as complex car seals, is equilibrium swelling. Measurements
Krzysztof Kaczewiak +2 more
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Arthritis &Rheumatology, Accepted Article.Background Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes and decreased nephrin production.
Rhea Bhargava +9 more
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