Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis
Angewandte Chemie International Edition, EarlyView.Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
wiley +1 more source
Novel Approaches For The Synthesis Of Amino Acids And Piperidines, Including Asymmetric Strategies [PDF]
, 2012 Chapter I deals with novel approaches for α-amino acids. This chapter has been divided into three sections. Section A describes the synthesis of α-amino acids via the Beckmann rearrangement of carboxyl-protected β-keto acid oximes.
Vippila, Mohana Rao
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Design and synthesis of a fragment set based on twisted bicyclic lactams
, 2018 Current fragment sets tend to be dominated by flatter molecules, and their shape diversity does not reflect that of the fragments that are theoretically possible.
Hassan, H, Marsden, S, Nelson, AS
core +1 more source
Frontispiece: Efficient Synthesis of Dimeric Oxazoles, Piperidines and Tetrahydroisoquinolines from N‐Substituted 2‐Oxazolones [PDF]
, 2016 Yun He +11 more
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Research progress of donepezil for treating mild to moderate Alzheimer's disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2017 Donepezil is the second generation of cholinesterase inhibitors (ChEIs), which has a good effect on mild to moderate Alzheimer's disease (AD). In recent years, there were a lot of studies on the mechanism of donepezil. This paper mainly introduces the
Xin-xin LI, Yun-yun ZHANG, Bin WANG
doaj
Mesoionic N‐Heterocyclic Olefins, Imines, Thiones, Phosphinidenes and Their Application in Catalysis
Angewandte Chemie International Edition, EarlyView.This minireview covers recent advances in the synthesis, reactivity, and metal‐free catalytic uses of mesoionic N‐heterocyclic olefins (mNHOs), imines (mNHIs), thiones (mNHTs), and phosphinidenes (mNHPs). Abstract Transition metal compounds are widely known for their ability to activate small molecules and are excellent catalysts for a wide range of ...
Subir Maji +3 more
wiley +1 more source
Genetic variation of piperidine alkaloids in Pinus ponderosa: a common garden study [PDF]
, 2008 Elizabeth A. Gerson +2 more
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BACE 1 (b-secretase), a membrane bound aspartic protease, is a key enzyme in the process of amyloid precursor protein (APP) into Ab peptide which is considered to play a causative role in Alzheimers Disease (AD). Here, we reported the synthesis and inhibitory activity of optically active 3-amino-4-aryl-piperidines. [PDF]
, 2006 Chan Ho Park
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Synthesis of fused tetrazolo iminosugars from azido monosaccharide derivatives [PDF]
, 2014 Synthesis of fused tetrazolo iminosugars from azido monosaccharide derivativesUniversidad de Málaga.
Pino-Gonzalez, Maria Soledad
core
II. SAR studies of pyridyl–piperazinyl-piperidine derivatives as CXCR3 chemokine antagonists
, 2010 Yuefei Shao +18 more
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