Results 151 to 160 of about 24,581 (324)

Asymmetric α-amidoalkylation. Synthesis of α-substituted piperidines of high enantiomeric purity [PDF]

, 1987
Kärtner, Annerose, Wanner, Klaus Th.
core   +1 more source

Synthesis of N-Substituted 1,6-Dihydro-3(2H)-pyridinones and 1-Acyl-3-piperidines

, 1984
Ling-Ching Chen, Eng-Chi Wang, Jen‐Hom Lin, S S Wu   +3 more
openalex   +1 more source

Synthesis of a novel analogue of DPP-4 inhibitor Alogliptin: Introduction of a spirocyclic moiety on the piperidine ring [PDF]

, 2010
Arumugam Kodimuthali, Padala Lakshmi Prasunamba, Manojit Pal   +2 more
openalex   +1 more source

Caffeine Content Assessment in Beverages and Food Supplements: Regulatory Challenges and Health Implications

ChemFoodChem, EarlyView.
ABSTRACT This study presents an analysis of caffeine content in food supplements and evaluates current regulatory frameworks against established safety guidelines. High‐caffeine products, particularly sports, and food supplements, were assessed for compliance with the safety opinion of the European Food Safety Authority (EFSA). The investigation during
Leonie Rinke, Ann‐Kathrin Kull, Verena Bock, Dirk W. Lachenmeier   +3 more
wiley   +1 more source

Stereocontrolled Synthesis of Piperidine-Condensed Tricyclic Carbapenems (5-Azatrinems) and Their Antibacterial Activities.

, 2000
Makoto Mori, Atsushi Somada, S. OIDA
openalex   +2 more sources

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

Chemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

I. Synthesis and Evaluation of Partially Fluorinated N-Alkyl Piperidines - II. Bicyclo3.2.0heptane as Core Structure for Conformational Locking of 1,3-bis-Pharmacophores, Exemplified by GABA

, 2016
Raffael Vorberg
openalex   +2 more sources

Catalytic Enantioselective Synthesis of 3-Piperidines from Arylboronic Acids and Pyridine [PDF]

, 2023
Sourabh Mishra, Sedef Karabıyıkoğlu, Stephen P. Fletcher   +2 more
openalex   +1 more source

Synthetic Studies towards Darobactin A

Chemistry – A European Journal, EarlyView.
The urgent need for new antibiotics led us to develop a new methodology for the synthesis of the natural product darobactin A selectively targeting gram‐negative bacteria. This study provides new insights into the synthesis of strained indole‐containing macrocycles.
Till Steiner, Antoine Versini, Marco Schellenberg, Emma Schuler, Karl Gademann   +4 more
wiley   +1 more source

The stereochemistry of the addition of chlorotitanium enolates of N-acyl oxazolidin-2-ones to 5- and 6- membered N-acyliminium ions

Journal of the Brazilian Chemical Society, 2001
The stereoselective addition of chiral and achiral titanium enolates derived from the corresponding N-acyl oxazolidin-2-ones to 5- and 6- membered N-acyliminium ions afforded 2-substituted pyrrolidines in moderate to good diastereoisomeric ratio (5:1 to ...
Pilli Ronaldo A., Böckelmann Maria Alice, Alves Conceição de Fatima   +2 more
doaj